17th DecVahitha Abdul Salam Proteomics approaches in Pulmonary Arterial Hypertension (PAH) - The CLIC story10th Decno seminar due to meeting clash
3rd DecSuchita Nadkarni A role for maternal inflammatory immune cells in abnormal embryonic heart development
26th Nov Qadeer AzizThe role of ATP-sensitive potassium channels in cardiovascular (patho)physiology
19th NovBarts Community Smiles (PPAG Team)Alcohol and the Body12th NovMarilena CrescenteProfiling the eicosanoid networks that underlie aspirin’s action in the cardiovascular system5th NovJames Whiteford Novel syndecan derived therapeutics for treating neovascular and fibrotic diseases29th OctMary Walker13-series resolvins in regulating vascular inflammation during arthritis
22nd OctPaul ArmstrongPlatelet-monocyte complexes in thrombo-inflammatory cardiovascular diseases
15th Oct Helen WarrenGenetic Analyses for Pharmacogenetic Response of Blood Pressure to Anti-Hypertensive Drugs: Using ASCOT and other datasetsSlides Helen Warren 15th Oct [PDF 266KB]8th OctAjay GuptaLipid-lowering therapy: the Good, the Bad, and the Fake
1st OctMatthew TraylorGenetic studies in cerebrovascular disease 24th SeptHarriet AllanPlatelet ageing is associated with changes in composition and function17th SeptDeepti Gurdasani Population History and Genomic Discovery in East Africa10th SeptClaudio RaimondiNeuropilin-1 and ATP-binding-cassette family member 8 (ABCB8) promote mitochondrial and endothelial cell homeostasis
3rd SeptDan JonesHigh Thrombus Burden in Patients with COVID-19 Presenting with ST-Elevation Myocardial Infarction20th Aug Qingbo XuApplication of Single Cell RNA-sequencing for the Study of Vascular Disease
12th March NEW SPEAKERMichael Shattock, King's FXYD1 phosphorylation regulates vascular tone, blood pressure and hypertension in mice and man
Cancelled: Due to outbreak of CoronavirusTakaaki Akaike, Tohoku University (Sendai, Japan) Emerging sulfur biology innovating vascular signaling and disease control
5th March Jillian Simon, University of OxfordNovel mechanisms of PKA-dependent calcium regulation
27th Feb Mariana Fernandez CaggianoMitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophySebastian GremerClassical and oxidative activation of PKGIa in the cardiovascular systems - Brothers in arms or opposing players?
9th DecProf Lisa Heather (University of Oxford)The battle between hypoxia and diabetes- targeting HIF to improve the diabetic heart
25th NovEdward T. Chouchani (Harvard Medical School)Mechanisms of metabolite regulation over health and disease
18th NovProf Pawel Swietach (University of Oxford) An alkaline milieu is conducive for cardiac contraction and hypertrophy
11th NovAndrea de la Fuente-Alonso, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, SpainAortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO
28th OctMark Ranek (Johns Hopkins University)Treating Cardiac Proteinopathies with Protein Kinase G Activators
21st OctCaroline RoneyPredicting atrial fibrillation recurrence: combining population data and patient-specific biophysical models14th OctProf Anja Karlstaedt (Smidt Heart Institute)Cardio-Oncology: Metabolic interactions between cancer and the heart
23rd SeptMiriam Cortese-Krott (University of Dusseldorf)Red blood cells and regulation of blood pressure16th SeptChristian Oeing (University Medicine Berlin)Redox-dependent mTOR signaling in Heart Failure
9th SeptPaul S. BrookesMethylglyoxal Metabolism and Cardiac Ischemia29th JulKyle McCommisRemodeling and reverse-remodeling the MPC-deficient heart
22nd JulSruti Shiva (University of Pittsburgh)Platelet mitochondria – a cardiovascular signaling hub
15th JulThomas Krieg (University of Cambridge)Succinate Dehydrogenase as a therapeutical target
8th JulProf Johannes Backs (Heidelberg University)Class IIa histone deacetylases in cardiac homeostasis and disease
1st JulProf Cristina Basso (University of Padua Medical School)Inflammation in myocardial diseases: the pathologist perspective17th JunMirela Delibegovic (University of Aberdeen)Targeting PTP1B for treatment of cardiovascular disease and diabetes3rd JunJunichi Sadoshima (Rutgers New Jersey Medical School)The role of the Hippo signaling in cardiac disease
10th JunSakthivel SadayappanDiastolic Dysfunction of South Asian (Dosa study)
27th MayBradford Hill (University of Louisville)Metabolic mechanisms of cardiac remodeling20th MayJamie TimmonsStrategies for using genomics for drug repurposing in metabolic disease13th May - BHF Accelerator Award SeminarPilar AlcaideT cell immune responses in heart inflammation and failure6th MaySarah De Val (University of Oxford)Understanding regulatory pathways controlling blood vessel behaviour throughout development and during cardiac injury29th AprilMairi Brittan (University of Edinburgh)Understanding endogenous mechanisms of vascular regeneration in the heart.22nd AprilGareth Purvis (University of Oxford)New insights into Bruton's tyrosine kinase (BTK): Macrophages in obesity and atherosclerosis
15th April - BHF Accelerator Award SeminarGabriele SchiattarellaCardiometabolic Alterations in Heart Failure with Preserved Ejection Fraction1st AprilGabrielle Fredman (Albany Medical College)Dysregulation of resolution in atherosclerosis25th MarProf Ralf Brandes (Goethe University Frankfurt)Long non-coding RNAs in endothelial function18th MarProf Sean Davidson (UCL)Exosomes - a promising therapeutic agent for myocardial infarction4th Mar - BHF Accelerator Award SeminarMarinos Kallikourdis Roles of T cells and their consequences for cardiovascular pathology25th FebWill Fuller (University of Glasgow)New tricks for old ion transporters: palmitoylation and the regulation of cardiac function 18th FebProf Jesmond DalliResolution pathways as novel targets in cardiovascular diseases
4th FebChristos BourantasImplications of the local hemodynamic forces on atherosclerotic evolution. From bench to bedside.
28th JanRebecca Charles Soluble epoxide hydrolase activation by intra-protein disulfide bond formation contributes to angiotensin II induced hypertension
21st JanFriederike Cuello (University of Hamburg)Molecular pathomechanisms in humans with mutations in Protein Kinase G I that cause cardiovascular disease
7th July
Dr Dianne Cooper (QMUL)
Cardiac dysfunction in rheumatoid arthritis: the role of inflammation
14th July
Dr Nicola Smart (University of Oxford)
Mechanisms of vascular protection and repair: insights from the developing embryo
21st July
Prof Jojo (Judith) Haendeler & Dr Yogi Altschmied (Heinrich Heine University)
The hitchhiker's guide to mitochondrial Telomerase Reverse Transcriptase in the cardiovascular system
28th July
Prof Sir Mark Caulfield (QMUL)
Cardiovascular Genomics
1st September
Dr Patrick Pagano (University of Pittsburgh School of Medicine)
Redox signalling and NOX1 rheostat in vascular phenotype modulation and disease
8th September
Dr Ivan Kadurin (QMUL)
Modulation of voltage-gated calcium channels in excitable cells
22nd September
Dr Nikolaos Frangogiannis (Albert Einstein College of Medicine)
Cardiac fibrosis
29th September
Dr Anja Hofman (University Hospital Dresden)
NOX4 is protective in carotid artery stenois
6th October
Dr Elena Goncharova (University of California Davis School of Medicine)
A 'tail' of two pathways: targeting HIPPO signalling in pulmonary hypertension
13th October
Dr David Thomas (Imperial College London)
EROS: A selective chaperone that controls reactive oxygen species and inflammasome activation
20th October
Prof Mauro Giacca (King's College London)
RNA therapies for cardiac regeneration and gene editing
10th November
Jane Batchelor & Dr David Collier (QMUL)
TBA
17th November
Prof Matthias Nahrendorf (MGH Research Institute / Harvard Medical School)
Myeloid cells in cardiovascular health
1st December
Associate Prof Benjamin L Prosser (University of Pennsylvania, Perelman School of Medicine)
Cytoskeletal control of cardiac growth and mechanics
8th December
Dr Angeliki Asimaki (St George's, University of London)
Arrythmogenic cardiomyopathy; shifting the needle from intuitive to precision medicine