Led by Professors Márta Korbonits and Lou Metherell, research activity in the Centre for Endocrinology spans between clinically applied research in endocrinology to basic research in endocrine signalling pathways. The Centre remains one of the leading centres in clinical endocrine research and practice worldwide and has been responsible for many of the current protocols for investigation and management of endocrine disease.
Clinical and research collaboration between paediatric and adult endocrinologists is delivering ground-breaking discoveries and an international patient referral base, providing access to unique patients and families. Our Discovery Science and Experimental Medicine successes include achieving major advances in understanding the nature and causes of Familial Pituitary Adenoma and identifying six novel genes causing Familial Glucocorticoid Deficiency, thereby providing new insights into the cellular processes regulating steroidogenesis. Adrenal and pituitary development, mitochondrial and stem cell physiology and intracellular trafficking are complementary ongoing research interests at Endocrinology, as is the study of novel genes underlying the timing of puberty, the risk of dyslipidemia and rare bone diseases.
The translational aspects of our work are both inspired and supported by our clinical and basic research collaboration, which continues to serve us well in attracting high-quality clinical and non-clinical PhD students and more senior investigators to this truly international centre of excellence.
Our partnership with Clinical Endocrinology at Barts Health NHS Trust at St. Bartholomew’s Hospital enables detailed studies of pathogenesis and therapeutic options for rare and common endocrine and metabolic diseases.
Professor Márta KorbonitsEmail: firstname.lastname@example.org
Professor Lou MetherellEmail: email@example.com