For a full list of publications click here

  • Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure. Bruschetta G, Kim JD, Diano S, Chan LF. Mol Metab. 2018 Dec;18:79-87. doi: 10.1016/j.molmet.2018.09.010. Epub 2018 Oct 4.

  • MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF.FASEB J. 2018 Jun 7:fj201701274RR. doi: 10.1096/fj.201701274RR. [Epub ahead of print] PMID: 29879378

  • Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn EH, Gorrigan RJ, Tate PH, Guasti L, Sanger Mouse Genetics P, O'Rahilly S, Clark AJ, Logan DW, Coll AP, & Chan LF (2016) Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol. J Endocrinol 230(1):13-26.

  • Samuelsson AS, Mullier A, Maicas N, Oosterhuis NR, Eun Bae S, Novoselova TV, Chan LF, Pombo JM, Taylor PD, Joles JA, Coen CW, Balthasar N, & Poston L (2016) Central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity. Proc Natl Acad Sci U S A 113(43):12298-12303.

  • Chan LF, Campbell DC, Novoselova TV, Clark AJ, & Metherell LA (2015) Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children. Front Endocrinol (Lausanne) 6:113.

  • Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstrale M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, & Majzoub JA (2013) Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science 341(6143):275-278.

  • Gorrigan RJ, Guasti L, King P, Clark AJ, & Chan LF (2011) Localisation of the melanocortin-2-receptor and its accessory proteins in the developing and adult adrenal gland. J Mol Endocrinol 46(3):227-232.

  • Chan LF, Webb TR, Chung TT, Meimaridou E, Cooray SN, Guasti L, Chapple JP, Egertova M, Elphick MR, Cheetham ME, Metherell LA, & Clark AJ (2009) MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family. Proc Natl Acad Sci U S A 106(15):6146-6151.