Professor Graham Davis, BSc(Eng), PhD
Professor of 3D X-ray Imaging
Email: firstname.lastname@example.orgTelephone: +44 20 7882 5967Room Number: 2.20.4 Francis Bancroft Building, Mile End Road.
Graham Davis graduated as an electronic engineer in 1980 and obtained a PhD in medical electronics in 1984. After working originally in the design of computerised electromyography apparatus, he moved to the London Hospital Medical College (now part of Queen Mary University of London) in 1988 and shortly thereafter began work on the development of X-ray microtomography (XMT). Designing scanners and software algorithms with accuracies exceeding commercially available systems, he is well recognised in this area of development and has served on the European Standards Committee CEN/TC 138/WG 1/AH 1 Computed Tomography. He also serves as a program committee member for the "Developments in X-ray Tomography" conference held every 2 years as part of The International Society for Optical Engineering's (SPIE) International Symposium on Optical Science, Engineering, and Instrumentation.
He is currently the lead for Imaging Sciences in the Centre for Oral Bioengineering, which includes electron microscopy, X-ray imaging, optical coherence tomography and facial scanning. His chief aim is to work alongside clinicians towards better understanding and treatment of dental conditions and has an additional interest in developing public engagement activities related to dentistry involving gaming and virtual reality. He also supports staff and student wellbeing at QMUL, helping to organise the QMUL running club, and is trained in mental health first aid.
Prof Davis teaches 3D X-ray imaging to dental postgraduates, as well as basic neurophysiology and associated clinical electrical measurements (EMG, EEG, etc.) to Medical Engineering students, He also teaches critical thinking to PhD students across QMUL and has delivered similar critical thinking sessions to Masters students. He is a supervisor for PhD, DClinDent and Masters students and QMUL Model tutor.
My main research interest is the design and application of advanced X-ray microtomography (XMT or micro-CT) systems. Unlike commercially available systems, these are optimised to produce high quality images giving an accurate representation of the mineral content in biological hard tissue. In dentistry for example, these can be used to precisely map and quantify mineral loss and gain in demineralisation and remineralisation respectively. The high contrast ratio available from these scanners allows us to study small differences in the degree of mineralisation throughout dentine and enamel. The unique availability of these instruments provides opportunities for clinical staff and research students to be involved in cutting edge research in these areas.
The use of this facility also spans many other disciplines including archaeology, palaeontology, petrology and materials science. The high sensitivity of the scanners has allowed us to recover text from damaged historical scrolls and this has been widely reported in the cultural heritage community. I am currently working with the BBC, recovering images from a severely degraded film reel.
Body wall structure in the starfish Asterias rubens. Blowes, L. M., Egertova, M., Liu, Y., Davis, G. R., Terrill, N. J., Gupta, H. S., & ELPHICK, M. R. Journal of Anatomy 2017, 231: 325–341.
Recovering historical film footage by processing microtomographic images. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2016, Vol. 10058 LNCS, pp. 219-231.
In vitro and in vivo study of commercial calcium phosphate cement HydroSet™. Kent, N. W., Blunn, G., Karpukhina, N., Davis, G., de Godoy, R. F., Wilson, R. M., . . . Hill, R. Journal of Biomedical Materials Research - Part B Applied Biomaterials 2016.
High contrast XMT studies of in-situ electrochemical dissolution of broken dental tools. Mills D, Mitchell A, Khine, S and Davis G. Proc. SPIE 9967, 99670D, (2016).
2D beam hardening correction for micro-CT of immersed hard tissue. Davis GR, Mills D. Proc. SPIE 9967, 996707, (2016).
Microscopic study of dental hard tissues in primary teeth with Dentinogenesis Imperfecta Type II: Correlation of 3D imaging using X-ray microtomography and polarising microscopy. G.R. Davis, J.M. Fearne, N. Sabel, J.G. Norén. Archives of oral biology 60, 2015, 1013-1020.
Characterisation of materials: determining density using X-ray microtomography. G. R. Davis; A. N. Z. Evershed; D. Mills. Materials Science and Technology 31 (2), 2015, 162-166.
Osteoblast-specific expression of the Fibrous Dysplasia (FD) causing mutation, GsαR201C produces a high bone mass phenotype but does not reproduce FD in the mouse. Remoli C, Michienzi S, Sacchetti B, Di Consiglio A, Cersosimo S, Spica E, Robey PG, Holmbeck K, Cumano A, Boyde A, Davis G, Saggio I, Riminucci M, Bianco P. J Bone Miner Res. 30 (6) 2014, 1030-1043.
Apocalypto. David Mills, Antoinette Curtis, Graham Davis, Paul Rosin, Yu-Kun Lai, Journal of Paper Conservation, 15(3), 2014, 15-19.
On fragmenting, densely mineralised acellular protrusions into articular cartilage and their possible role in osteoarthritis. A. Boyde, G. R. Davis, D. Mills, T. Zikmund, T. M. Cox, V. L. Adams, A. Niker, P. J. Wilson, J. P. Dillon, L. R. Ranganath, N. Jeffery, J. C. Jarvis and J. A. Gallagher. J. Anat.2014, 225, 436—446.
Brute force absorption contrast microtomography. Davis GR, Mills D. Proc SPIE 9212, 92120I1 (2014).
Apocalypto: revealing lost text with XMT. Mills D, Davis GR, Lai K, Rosin P, Proc SPIE 9212, 921210 (2014).
Is there evidence for change to collagen within parchment samples after exposure to an X-ray dose during high contrast X-ray microtomography? A multi technique investigation. Patten, K., Gonzalez, L., Kennedy, C., Mills, D., Davis, G., Wess, T., Heritage Science 1(1) 2013, 22.
Quantitative high contrast X-ray microtomography for dental research. Davis GR, Evershed ANZ, Mills D. J Dent 41(5): 475-482, 2013.