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Institute of Dentistry - Faculty of Medicine and Dentistry

Dr Natalia Karpukhina, PhD


Reader in Dental Physical Sciences

Telephone: +44 (0)207 882 5975
Room Number: Office 2.21.2, Francis Bancroft Building, Mile End Campus


Nov 2009 – present
Lecturer, Centre for Oral Growth and Development, Barts and The London School of Medicine and Dentistry, Queen Mary University of London.

May 2007 – Oct 2009
Research Associate, Department of Chemistry, Department of Materials, Imperial College London.

Nov 2005 – Apr 2007
Research Associate, Department of Chemistry, Dalhousie University, Halifax, Canada

Jun 2004 – Jun 2005
Guest Scientist, Max-Planck Institute for Metals Research, Stuttgart, Germany

Dec 2001 – May 2004
Post Doctoral Research Associate, Department of Physical Chemistry, St.Petersburg State University, St.Petersburg, Russia.

Nov 2001
PhD in Physical Chemistry, Department of Physical Chemistry, St.Petersburg State University, St.Petersburg, Russia.

Centre: Oral Bioengineering


Along with the rest of the dental materials team, I teach dental materials to UG and PG students and supervise the research projects.


Research Interests:

I am working in the area of dental and biomedical materials. I use solid-state nuclear magnetic resonance (NMR) spectroscopy to investigate structure of these materials. This technique is powerful and informative to resolve the structure of amorphous and crystalline solids. We study structure of bioactive silicate and phosphate glasses containing halogen and other components. We investigate the setting reactions in dental materials using solid-state NMR among other techniques. We study structure and properties of dental glass-ceramics and various substitutions in apatites. Using solid-state NMR and in combination with other techniques, we study structure of teeth, bones and other natural apatites. We apply our knowledge on structure of natural and synthetic materials for development future materials for specific applications.


  1. O'Donnell MD, Hill RG, Karpukhina N, Law RV. Real time neutron diffraction and NMR of the Empress II glass-ceramic system. Dental Mater (2011) 27:990-996
  2. Abo-Mosallam HA, Hill RG, Karpukhina N, Law RV. MAS-NMR studies of glasses and glass-ceramics based on a clinopyroxene-fluoroapatite system, J Mater Chem (2010) 20:790-797
  3. Munhoz T, Karpukhina N, Hill RG, Law RV. Setting of commercial glass ionomer cement Fuji IX by 27Al and 19F MAS-NMR. J Dent (2010) 38:325-330
  4. Brauer DS, Karpukhina N, O'Donnell MD, Law RV, Hill RG. Fluoride-containing bioactive glasses: Effect of glass design and structure on degradation, pH and apatite formation in simulated body fluid. Acta Biomater (2010) 6:3275-3282
  5. Hill RG, O'Donnell MD, Law RV, Karpukhina N, Cochrane B, Tulyaganov D. The early stages of nucleation and crystallisation of an apatite glass-ceramic: Evidence for nano-scale crystallisation. J Non-Cryst Solids (2010) 356:2935-2941

All publications

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