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Professor Steffen Petersen

Steffen

Professor of Cardiovascular Medicine

Centre: Advanced Cardiovascular Imaging

Email: s.e.petersen@qmul.ac.uk
Twitter: @s_e_petersen

Profile

ORCID iD: 0000-0003-4622-5160
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Steffen Petersen is a Professor of Cardiovascular Medicine at William Harvey Research Institute, Queen Mary University of London and a Consultant Cardiologist at Barts Heart Centre, Barts Health NHS Trust. He is the British Heart Foundation Data Science Centre Deputy Director. He is President of the European Society of Cardiology's (ESC) European Association of Cardiovascular Imaging (EACVI). He holds an MBCHB and MDRES equivalent (Dr med.) from Johannes Gutenberg University Mainz, Germany, a DPHIL (OXON) from the Department of Cardiovascular Medicine, University of Oxford, an MPH from Harvard School of Public Health and an MSc from the London School of Economics. He is level 3 certified for cardiovascular magnetic resonance (CMR). He has been actively involved in cardiovascular magnetic resonance since 1998 and he reports over 1000 cardiac adult MRI scans each year.

Memberships and awards

•    Fellow of the Society for Cardiovascular Magnetic Resonance (FSCMR)
•    Fellow of the European Society of Cardiovascular Imaging (FEACVI)
•    Fellow of the Japanese Circulation Society (FJCS)
•    Senior Fellow of the Higher Education Academy (SFHEA)
•    Fellow of Royal College of Physicians (FRCP)
•    Fellow of the American College of Cardiology (FACC)
•    Fellow of the European Society of Cardiology (FESC)
•    Fellow of the Alan Turing Institute

Research

Group members

Centre leadership:

  • Centre lead and Principal Investigator: Steffen E Petersen, Professor of Cardiovascular Medicine
  • Deputy Centre lead and Principal Investigator: Francesca Pugliese, Reader

Core staff:

  • Centre and events manager:  Jane Batchelor
  • Assistant Director - Health and Imaging Informatics: Aaron Lee
  • Senior Statistician and Data Scientist: Ahmed Salih

Senior (postdoc) researchers (* if honorary):

Mohammed Khanji* (Reader); Guy Lloyd* (Senior Clinical Lecturer); Sanjeev Bhattacharyya* (Senior Clinical Lecturer); Dr Magnus T. Jensen* (Senior Clinical Lecturer, based in Copenhagen); Dr Jose Vargas* (Senior Clinical Lecturer, based in Washington DC); Marc Miquel* (Senior Lecturer); Nay Aung (NIHR Academic Clinical Lecturer); Zahra Raisi-Estabragh (NIHR Academic Clinical Lecturer); Dr Musa Abdulkareem*, Postdoc (based in Leicester); Liliana Szabo (Postdoc)

PhD students (^ if clinical):

Mihir Sanghvi^; Vijay Shyam Sundar^; Sucharitha Chadalavada^; Hafiz Naderi^; James Malcolmson; Bunny Saberwal^; Elisa Rauseo^; Shahid Karim^; Kerrick Hesse^; Sveeta Badiani; Nikhil Ahluwalia^; Celeste McCracken (registered at University of Oxford); Jawza Aldakhil

Junior researchers (*if honorary):

Dorina Condurache; Gracia Andriamiadana; Ross Thomson (NIHR Academic Clinical Fellow); Adil Mahmood (NIHR Academic Clinical Fellow)

Summary

Professor Petersen’s research typically involves cardiovascular magnetic resonance (CMR) acquired in clinical or research settings and forms an important component of research work in cardiovascular epidemiology, non-invasive (imaging) biomarker development and assessing the value of cardiac imaging in prevention, diagnosis, risk assessment and management of cardiovascular diseases. He pioneered many artificial intelligence applications in cardiovascular imaging in multi-disciplinary collaborations. Most of the research data comes from large-scale population studies with cardiac imaging (e.g. UK Biobank, Petersen is co-lead for cardiac imaging), clinical registries and cohorts (Petersen is Principal and Chief Investigator of the Barts BioResource) and electronic health care records and other digital healthcare data. 

Key Publications

For a full list of publications click here. Relevant metrics are listed on Google Scholar.

  1. Zemrak F, Ahlman MA, Captur G, Mohiddin SA, Kawel-Boehm N, Prince MR, Moon JC, Hundley WG, Lima JA, Bluemke DA and Petersen SE. The relationship of left ventricular trabeculation to ventricular function and structure over a 9.5-year follow-up: the MESA study. J Am Coll Cardiol. 2014;64:1971-80.
  2. Captur G, Zemrak F, Muthurangu V, Petersen SE, Li C, Bassett P, Kawel-Boehm N, McKenna WJ, Elliott PM, Lima JA, Bluemke DA and Moon JC. Fractal Analysis of Myocardial Trabeculations in 2547 Study Participants: Multi-Ethnic Study of Atherosclerosis. Radiology. 2015;277:707-15.
  3. Rider OJ, Lewis AJ, Lewandowski AJ, Ntusi N, Nethononda R, Petersen SE, Francis JM, Pitcher A, Banerjee R, Leeson P and Neubauer S. Obese subjects show sex-specific differences in right ventricular hypertrophy. Circ Cardiovasc Imaging. 2015;8.
  4. Petersen SE, Matthews PM, Francis JM, Robson MD, Zemrak F, Boubertakh R, Young AA, Hudson S, Weale P, Garratt S, Collins R, Piechnik S and Neubauer S. UK Biobank's cardiovascular magnetic resonance protocol. J Cardiovasc Magn Reson. 2016;18:8.
  5. Shah RV, Anderson A, Ding J, Budoff M, Rider O, Petersen SE, Jensen MK, Koch M, Allison M, Kawel-Boehm N, Wisocky J, Jerosch-Herold M, Mukamal K, Lima JAC and Murthy VL. Pericardial, But Not Hepatic, Fat by CT Is Associated With CV Outcomes and Structure: The Multi-Ethnic Study of Atherosclerosis. JACC Cardiovasc Imaging. 2017;10:1016-1027.
  6. Zemrak F, Ambale-Venkatesh B, Captur G, Chrispin J, Chamera E, Habibi M, Nazarian S, Mohiddin SA, Moon JC, Petersen SE, Lima JA and Bluemke DA. Left Atrial Structure in Relationship to Age, Sex, Ethnicity, and Cardiovascular Risk Factors: MESA (Multi-Ethnic Study of Atherosclerosis). Circ Cardiovasc Imaging. 2017;10.
  7. Aung N, Sanghvi MM, Zemrak F, Lee AM, Cooper JA, Paiva JM, Thomson RJ, Fung K, Khanji MY, Lukaschuk E, Carapella V, Kim YJ, Munroe PB, Piechnik SK, Neubauer S and Petersen SE. Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study. Circulation. 2018;138:2175-2186.
  8. Bai W, Sinclair M, Tarroni G, Oktay O, Rajchl M, Vaillant G, Lee AM, Aung N, Lukaschuk E, Sanghvi MM, Zemrak F, Fung K, Paiva JM, Carapella V, Kim YJ, Suzuki H, Kainz B, Matthews PM, Petersen SE, Piechnik SK, Neubauer S, Glocker B and Rueckert D. Automated cardiovascular magnetic resonance image analysis with fully convolutional networks. J Cardiovasc Magn Reson. 2018;20:65.
  9. Aung N, Vargas JD, Yang C, Cabrera CP, Warren HR, Fung K, Tzanis E, Barnes MR, Rotter JI, Taylor KD, Manichaikul AW, Lima JAC, Bluemke DA, Piechnik SK, Neubauer S, Munroe PB and Petersen SE. Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure Development. Circulation. 2019;140:1318-1330.
  10. Fung K, Ramirez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE and Munroe PB. Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants. Sci Rep. 2019;9:9143.
  11. Jensen MT, Fung K, Aung N, Sanghvi MM, Chadalavada S, Paiva JM, Khanji MY, de Knegt MC, Lukaschuk E, Lee AM, Barutcu A, Maclean E, Carapella V, Cooper J, Young A, Piechnik SK, Neubauer S and Petersen SE. Changes in Cardiac Morphology and Function in Individuals With Diabetes Mellitus: The UK Biobank Cardiovascular Magnetic Resonance Substudy. Circ Cardiovasc Imaging. 2019;12:e009476.
  12. Aung N, Doimo S, Ricci F, Sanghvi MM, Pedrosa C, Woodbridge SP, Al-Balah A, Zemrak F, Khanji MY, Munroe PB, Naci H and Petersen SE. Prognostic Significance of Left Ventricular Noncompaction: Systematic Review and Meta-Analysis of Observational Studies. Circ Cardiovasc Imaging. 2020;13:e009712.
  13. Aung N, Khanji MY, Munroe PB and Petersen SE. Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study. Front Genet. 2020;11:586308.
  14. Aung N, Sanghvi MM, Piechnik SK, Neubauer S, Munroe PB and Petersen SE. The Effect of Blood Lipids on the Left Ventricle: A Mendelian Randomization Study. J Am Coll Cardiol. 2020;76:2477-2488.
  15. Bai W, Suzuki H, Huang J, Francis C, Wang S, Tarroni G, Guitton F, Aung N, Fung K, Petersen SE, Piechnik SK, Neubauer S, Evangelou E, Dehghan A, O'Regan DP, Wilkins MR, Guo Y, Matthews PM and Rueckert D. A population-based phenome-wide association study of cardiac and aortic structure and function. Nat Med. 2020;26:1654-1662.
  16. Cetin I, Raisi-Estabragh Z, Petersen SE, Napel S, Piechnik SK, Neubauer S, Gonzalez Ballester MA, Camara O and Lekadir K. Radiomics Signatures of Cardiovascular Risk Factors in Cardiac MRI: Results From the UK Biobank. Front Cardiovasc Med. 2020;7:591368.
  17. Ferdian E, Suinesiaputra A, Fung K, Aung N, Lukaschuk E, Barutcu A, Maclean E, Paiva J, Piechnik SK, Neubauer S, Petersen SE and Young AA. Fully Automated Myocardial Strain Estimation from Cardiovascular MRI-tagged Images Using a Deep Learning Framework in the UK Biobank. Radiol Cardiothorac Imaging. 2020;2:e190032.
  18. Littlejohns TJ, Holliday J, Gibson LM, Garratt S, Oesingmann N, Alfaro-Almagro F, Bell JD, Boultwood C, Collins R, Conroy MC, Crabtree N, Doherty N, Frangi AF, Harvey NC, Leeson P, Miller KL, Neubauer S, Petersen SE, Sellors J, Sheard S, Smith SM, Sudlow CLM, Matthews PM and Allen NE. The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions. Nat Commun. 2020;11:2624.
  19. Raisi-Estabragh Z, McCracken C, Ardissino M, Bethell MS, Cooper J, Cooper C, Harvey NC and Petersen SE. Renin-Angiotensin-Aldosterone System Blockers Are Not Associated With Coronavirus Disease 2019 (COVID-19) Hospitalization: Study of 1,439 UK Biobank Cases. Front Cardiovasc Med. 2020;7:138.
  20. Raisi-Estabragh Z, McCracken C, Bethell MS, Cooper J, Cooper C, Caulfield MJ, Munroe PB, Harvey NC and Petersen SE. Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank. J Public Health (Oxf). 2020;42:451-460.
  21. Ricci F, Aung N, Gallina S, Zemrak F, Fung K, Bisaccia G, Paiva JM, Khanji MY, Mantini C, Palermi S, Lee AM, Piechnik SK, Neubauer S and Petersen SE. Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort. J Cardiovasc Magn Reson. 2020;23:5.
  22. Bard A, Raisi-Estabragh Z, Ardissino M, Lee AM, Pugliese F, Dey D, Sarkar S, Munroe PB, Neubauer S, Harvey NC and Petersen SE. Automated Quality-Controlled Cardiovascular Magnetic Resonance Pericardial Fat Quantification Using a Convolutional Neural Network in the UK Biobank. Front Cardiovasc Med. 2021;8:677574.
  23. Chadalavada S, Jensen MT, Aung N, Cooper J, Lekadir K, Munroe PB and Petersen SE. Women With Diabetes Are at Increased Relative Risk of Heart Failure Compared to Men: Insights From UK Biobank. Front Cardiovasc Med. 2021;8:658726.
  24. Lopes LR, Aung N, van Duijvenboden S, Munroe PB, Elliott PM and Petersen SE. Prevalence of Hypertrophic Cardiomyopathy in the UK Biobank Population. JAMA Cardiol. 2021;6:852-854.
  25. Petersen SE, Friedrich MG, Leiner T, Elias MD, Ferreira VM, Fenski M, Flamm SD, Fogel M, Garg R, Halushka MK, Hays AG, Kawel-Boehm N, Kramer CM, Nagel E, Ntusi NAB, Ostenfeld E, Pennell DJ, Raisi-Estabragh Z, Reeder SB, Rochitte CE, Starekova J, Sucha D, Tao Q, Schulz-Menger J and Bluemke DA. Cardiovascular Magnetic Resonance for Patients With COVID-19. JACC Cardiovasc Imaging. 2021.
  26. Rabbat MG, Kwong RY, Heitner JF, Young AA, Shanbhag SM, Petersen SE, Selvanayagam JB, Berry C, Nagel E, Heydari B, Maceira AM, Shenoy C, Dyke C, Bilchick KC and Society for Cardiovascular Magnetic R. The Future of Cardiac Magnetic Resonance Clinical Trials. JACC Cardiovasc Imaging. 2021.
  27. Raisi-Estabragh Z, M'Charrak A, McCracken C, Biasiolli L, Ardissino M, Curtis EM, Aung N, Suemoto CK, Mackay C, Suri S, Nichols TE, Harvey NC, Petersen SE and Neubauer S. Associations of cognitive performance with cardiovascular magnetic resonance phenotypes in the UK Biobank. Eur Heart J Cardiovasc Imaging. 2021.
  28. Raisi-Estabragh Z, McCracken C, Condurache D, Aung N, Vargas JD, Naderi H, Munroe PB, Neubauer S, Harvey NC and Petersen SE. Left atrial structure and function are associated with cardiovascular outcomes independent of left ventricular measures: a UK Biobank CMR study. Eur Heart J Cardiovasc Imaging. 2021.
  29. Raisi-Estabragh Z, McCracken C, Gkontra P, Jaggi A, Ardissino M, Cooper J, Biasiolli L, Aung N, Piechnik SK, Neubauer S, Munroe PB, Lekadir K, Harvey NC and Petersen SE. Associations of Meat and Fish Consumption With Conventional and Radiomics Cardiovascular Magnetic Resonance Phenotypes in the UK Biobank. Front Cardiovasc Med. 2021;8:667849.
  30. Simon J, Fung K, Kolossvary M, Sanghvi MM, Aung N, Paiva JM, Lukaschuk E, Carapella V, Merkely B, Bittencourt MS, Karady J, Lee AM, Piechnik SK, Neubauer S, Maurovich-Horvat P and Petersen SE. Sex-specific associations between alcohol consumption, cardiac morphology, and function as assessed by magnetic resonance imaging: insights from the UK Biobank Population Study. Eur Heart J Cardiovasc Imaging. 2021;22:1009-1016.

Sponsors

  

Collaborators

Internal 

External

  • Stefan Neubauer and colleagues (Oxford)
  • Karim Lekadir and colleagues (Barcelona)
  • Nick Harvey (Southampton)
  • Jose Vargas (Washington DC)
  • Magnus T Jensen (Copenhagen)

Commercial

  • Circle Cardiovascular Imaging, Inc.(Calgary, Canada)
  • Neosoft
  • Siemens
  • NVIDIA

News

Teaching

  • Prof Petersen has vast experience in successful supervision of clinical and non-clinical PhD students and help shape careers.
  • Prof Petersen co-leads the clinical trials and regulatory affairs module (BMD378)
  • Prof Petersen supervises student selected components (SSC) related to cardiology and supports multi-disciplinary students in gaining research experiences in his team.
  • Prof Petersen is an international leader in cardiovascular magnetic resonance and teaches at many national and international courses and conferences
  • Prof Petersen co-leads the European Association of Cardiovascular Imaging (EACVI) cardiovascular magnetic resonance exam prep course
  • Prof Petersen as President of the European Association of Cardiovascular Imaging (EACVI) sets the strategy and standards and contributes to the delivery of multi-modality cardiac imaging worldwide
  • Professor Petersen co-edited the popular EACVI Textbook of Cardiovascular Magnetic Resonance textbook

DataCamp

DataCamp offers online tutorials and courses to help students learn R and Python for data science. You can try their free courses here:


 

Disclosures

  • Professor Petersen provides consultancy to Circle Cardiovascular Imaging, Inc., Calgary, Alberta, Canada.
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