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Professor Patricia McGettigan

Patricia

Patricia McGettigan, Professor of Clinical Pharmacology and Medical Education (HCC)

Centre: Clinical Pharmacology and Precision Medicine

Email: p.mcgettigan@qmul.ac.uk
Telephone: +44(0) 20 7882 7128

Profile

ORCID iD: 0000-0002-9757-9754

Patricia McGettigan is a Clinical Pharmacologist and Consultant Physician at Queen Mary University of London (QMUL) and Barts Health NHS Trust. She graduated in pharmacy and in medicine from the University of Dublin, Trinity College and trained in Clinical Pharmacology at Trinity College, Dublin and the University of Newcastle, New South Wales, Australia. She is head of MBBS clinical pharmacology, therapeutics and prescribing teaching at QMUL and co-leads final year Clinical Trials and Regulatory Affairs teaching in QMUL’s BSc in Pharmacology and Innovative Therapeutics.

She is Deputy Chair of the Medical Schools Council’s national Prescribing Safety Assessment Standard Setting Group and an External Examiner for pharmacology at University College Cork, Ireland. In her clinical role, based at Barts Health Royal London Hospital, she cares for cardiology in-patients and provides specialist HIV-cardiovascular risk management for out-patients.

She is a Fellow of the Royal College of Physicians in Ireland, the Royal Australasian College of Physicians and the British Pharmacological Society and a Senior Fellow of the Higher Education Academy. Active in both national and European medicines regulation, she is a Member of the UK’s Commission on Human Medicines Pharmacovigilance Expert Advisory Group and is appointed by the European Commission to the Pharmacovigilance and Risk Management Committee of the European Medicines Agency.

Research

Patricia McGettigan’s research focuses on pharmacoepidemiology and medicines regulation using large health registers, drug sales databases, and regulatory records. In pharmacoepidemiology, major interests relate to drug-associated adverse events, medicines utilisation, and HIV-co-morbidities. Her regulatory research is on the authorisation of medicines, including fixed dose combination products and regulatory system failures in India, and the role of patient/disease registries in supporting post-authorisation medicines evaluation.

Key Publications

Full list of publications

2013 - 2023

  1. Holt A, Strange J, Nouhravesh N, Nielsen SK, Malik ME, Schjerning A-M, Køber L, Torp-Pedersen, Gislason GH, McGettigan P, Schou M, Lamberts M. (2023) Heart failure following anti-inflammatory medications in patients with Type 2 Diabetes Mellitus. J Am Coll Cardiol; 81(15):1459–1470. 
  2. Metha A, Brhlikova P, McGettigan P, Pollock AM, Roderick P, Hasan Farooqui H. (2022) Systemic Antibiotic sales and WHO recommendations, India. World Health Organ: 100(10):610–619. doi: 10.2471/BLT.22.287908
  3. Morales DR, Moreno-Martos D, Matin M, McGettigan P. (2022) Health conditions in adults with HIV compared with the general population: A population-based cross-sectional analysis. Lancet EClinicalMedicine 47, 101392
  4. Holt A, Blanche P, Zareini B, Rajan D, El-Sheikh M, Schjerning AM, Schou M, Torp-Pedersen C, McGettigan P, Gislason GH, Lamberts M. (2021). Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study. Eur Heart J; 42(9):907 - 914. 1093/eurheartj/ehaa1058
  5. Lovegrove E, Robson J, McGettigan P. (2020) Pregnancy protection and pregnancies in women prescribed angiotensin-converting enzyme inhibitors/angiotensin receptor blockers. Br J Gen Pract; DOI: 10.3399/bjgp20X712997
  6. Schuster Bruce C, Brhlikova P, Heath J, McGettigan P. (2019) The use of validated and non-validated surrogate endpoints in two European Medicines Agency expedited approval pathways: A cross-sectional study of products authorised 2011-2018. PLoS Med; 16(9):e1002873. doi:10.1371/journal.pmed.1002873
  7. McGettigan P, Alonso CO, Plueschke K, Castillon M, Nogueras DZ, Bahri P, Kurz X, Mol P. (2019) Patient registries: an underused resource for medicines evaluation: Operational proposals for increasing the use of patient registries in regulatory assessments. Drug Safety; 42:1343-51. doi.org/10.1007/s40264-019-00848-9.
  8. McGettigan P, Roderick P, Kadam A, Pollock A (2018) Threats to global antimicrobial resistance control: Centrally approved and unapproved antibiotic formulations sold in India. BJCP DOI:10.1111/bcp.13503.
  9. McGettigan P, Roderick P, Kadam A, Pollock A (2017) Access, Watch and Reserve Antibiotics in India: Challenges for WHO stewardship. Lancet GH, DOI: doi.org/10.1016/S2214-109X(17)30365-0.
  10. Schjerning Olsen AM, Gislason GH, McGettigan P, Fosbøl E, Sørensen R, Lock Hansen M, Køber L, Torp-Pedersen C, Lamberts M. (2015) Association of NSAID use with risk of bleeding and cardiovascular events in patients receiving antithrombotic therapy after myocardial infarction. JAMA; 313(8):805-814.
  11. Schjerning Olsen AM, Lindhardsen J, Gislason GH, McGettigan P, Hlatky MA, Fosbøl E, Køber L, Torp-Pedersen C, Lamberts M. (2015) Impact of PPI treatment on gastrointestinal bleeding associated with NSAID use among post-myocardial infarction patients on antithrombotic therapy - A nationwide study. BMJ 2015; 351:h509.
  12. McGettigan P, Roderick P, Mahajan R, Kadam A, Pollock A (2015) Use of Fixed Dose Combination (FDC) drugs in India: Central regulatory approval and sales of FDCs containing non-steroidal anti-inflammatory drugs (NSAIDs), metformin, or psychotropic drugs. PLoS Med; 12(5): e1001826.
  13. McGettigan P, Henry D (2013) Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries. PLoS Med; doi.org/10.1371/journal.pmed.1001388.
  14. McGettigan P, McKendree J, Reed N, Holborow S, Deveraux-Walsh C, Mace T (2013) Identifying attributes required by Foundation Year 1 doctors in multidisciplinary teams: A tool for performance evaluation. BMJ Qual Saf 2013; 22:225-232. 

Collaborators

University of Copenhagen, Denmark: Dr Anne-Marie Schjerning-Olsen, Dr Morten Lamberts, Professor Gunnar Gislason; University of Newcastle, UK: Dr Petra Sevcikova, Mr Peter Roderick, Professor Allyson Pollock; Indian Council of Medical Research: Professor Nilima Krishsagar; Public Health Foundation of India: Dr Habib Hasan Farooqui; University of Dundee, Scotland: Dr Daniel Morales.

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