Professor Charles Hinds
Professor (Emeritus) and Consultant in Intensive Care Medicine
Centre: Translational Medicine and Therapeutics
Email: c.j.hinds@qmul.ac.ukTelephone: +44(0) 20 3765 8878
Profile
Charles Hinds qualified at St. Bartholomew’s Hospital in 1972 and was appointed as Consultant and Senior Lecturer in Anaesthesia and Intensive Care at the same hospital in 1980. Subsequently, he was Director of the Intensive Unit at Barts, and later for the combined Barts and The London NHS Trust, for more than 15 years. He is a past President of the Intensive Care Society and was Chairman of Examiners for the UK Diploma of Intensive Care. He was UK Representative for the European Society of Intensive Care Medicine and a member of the Education and Training Subcommittee of the ESICM. He was for many years a member of the Research Committee of the Intensive Care Society. In January 2007 Professor Hinds was awarded a College Medal by the Royal College of Anaesthetists as a mark of distinction for his work in helping the College to achieve its aims and for his support for the speciality. He was subsequently invited to deliver the Samuel Thompson Rowling oration at the College. In 2013 Prof. Hinds was awarded Honorary Lifetime Memberships of the ESICM and UK Intensive Care Society. Together with Prof. Watson, Professor Hinds has published three editions of their popular textbook: Intensive Care: A concise textbook. Professor Hinds was recently awarded a Gold Medal by the Faculty of Intensive Care Medicine.
Memberships and awards
- Honorary Lifetime Member of the European Society of Intensive Care Medicine and the UK Intensive Care Society
- Royal College of Anaesthetists College Medal
- Gold Medal of the Faculty of Intensive Care Medicine
Research
Critical Care and Perioperative Medicine Research Group
Group members
- Professor Gareth Ackland
- Professor Mark Griffiths
- Professor Rupert Pearse
- Dr John Prowle
- Dr Zudin Pulthucheary
- Dr Parjam Zolfaghari
- Dr Alastair Proudfoot
Summary
Professor Hinds’ research interests have included the pathophysiology and treatment of sepsis, “goal-directed” haemodynamic therapy, endocrine aspects of critical illness, critical illness polyneuromyopathy and intensive care for patients with malignancy. Professor Hinds helped to establish the UK Critical Care Genomics Group which has recently completed a large National investigation (ukccggains.com), as well as being National Co-ordinator for the European “GenOSept” study (ESICM). Currently the group focusses on “multi-omic” approaches to the investigation of sepsis (GAinS2/Sepsis Immunomics), recently including COVID. Other current research interests include the host response to high-risk surgery.
Publications
-
Antcliffe DB, Mi Y, Santhakumaran S et al. (2024). Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes. nameOfConference
QMRO: qmroHref -
Torrance HD, Zhang P, Longbottom ER et al. (2024). A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery. nameOfConference
-
Kwok AJ, Allcock A, Ferreira RC et al. (2023). Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis. nameOfConference
QMRO: qmroHref -
Cano-Gamez E, Burnham KL, Goh C et al. (2022). An immune dysfunction score for stratification of patients with acute infection based on whole-blood gene expression. nameOfConference
QMRO: qmroHref -
Baillie JK, Begg C, Clohisey Hendry S et al. (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. nameOfConference
-
Consortium CM-OBA, Ahern DJ, Ai Z et al. (2022). A blood atlas of COVID-19 defines hallmarks of disease severity and specificity. nameOfConference
-
Milind N, Burnham KL, Lee W et al. (2022). Multi-omics integration to characterise mechanisms of molecular QTL from a sepsis cohort. nameOfConference
DOI: doi
-
Niemi MEK, Karjalainen J, Liao RG et al. (2021). Mapping the human genetic architecture of COVID-19. nameOfConference
-
Pairo-Castineira E, Clohisey S, Klaric L et al. (2021). Genetic mechanisms of critical illness in COVID-19.. nameOfConference
-
Smith A, Edlin J, Hinds C et al. (2020). Coronary revascularisation in cardiac amyloidosis. nameOfConference
DOI: 10.1111/jocs.14985
QMRO: qmroHref
Collaborators
External
- Professor Julian Knight (Wellcome Trust Centre for Human Genomics, Oxford)
- Professor Tony Gordon (Imperial College)
- Dr Emma Davenport (Sanger Institute, Cambridge)
- Dr Kate Burnham (Sanger Institute, Cambridge)