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The William Harvey Research Institute - Faculty of Medicine and Dentistry

Professor Maralyn Druce

Maralyn

Professor of Endocrine Medicine, Deputy Dean for Education (Postgraduate Taught Programmes) – Faculty of Medicine and Dentistry


Centre: Endocrinology

Email: m.r.druce@qmul.ac.uk
Telephone: +44(0) 20 7882 8284
Website: www.postgrad.bartsendocrinology.co.uk

Profile

ORCID iD: 0000-0003-1436-1969

Professor Maralyn Druce undertook undergraduate training at Christ's College, Cambridge University and completed her clinical training at University College and Middlesex School of Medicine in 1994. She completed her higher medical training in Diabetes, Endocrinology and General Internal Medicine at the Hammersmith Hospital and Barts Hospital. She was awarded a Wellcome Trust clinical research training fellowship and obtained a PhD in physiology in Professor Steve Bloom's laboratory in Imperial College, focusing on gut hormones and their role in the peripheral and central control of energy homeostasis.

Maralyn went on to be awarded the Chadburn Lectureship at Barts and the London School of Medicine and has remained here since then. She has a keen interest in teaching and completed her Masters in Medical Education (Dundee) in 2016. She is now Professor of Endocrine Medicine and Consultant Physician and Endocrinologist at Barts Health NHS Trust. Her clinical interests and activities are focussed on specialist clinical endocrinology with a particular focus on multidisciplinary management of patients with neuroendocrine tumours and on women’s health with additional certification in menopause care.

Current QMUL roles include Deputy Dean for Education (Postgraduate Taught Programmes) and Head of Governance for the Undergraduate MBBS and Dental programmes in FMD. She is also Associate Dean for Undergraduates at the St Bartholomew’s Hospital site.

She has carried out a number of external roles including Chair of the Society for Endocrinology Public Engagement Committee, Chair of the Education and Training Committee for UKINETs, member of the exam board for the Royal College of Physicians Diabetes and Endocrinology exam, Editor in Chief of Endocrinology, Diabetes and Metabolism Case Reports and Clinician-in-Practice Chair for the Endocrine Society annual meeting.

She is currently Senior Editor of the Journal ‘Clinical Endocrinology’, leads the Society for Endocrinology annual training meeting ‘Clinical Update’ and is a member of the Endocrine Society nominations committee.

Research

Group members
Dr Gabriela Mihai

Summary

Research interests include:

  • Pathophysiology, diagnosis and treatment of neuroendocrine tumours including fibrosis in the carcinoid syndrome, the use of targeted radionuclide therapy in the treatment of endocrine malignancy and the diagnosis and localisation of insulinoma. She is also involved in industry-sponsored clinical trials of novel pharmacological therapies
  • Factors affecting the production of catecholamines and metanephrines
  • Endocrine effects of cancer therapies
  • Gut hormones in the pathophysiology and treatment of obesity.

Memberships and awards

  • Fellow of the Royal College of Physicians
  • Member of the Society for Endocrinology (and lead for Clinical Update)
  • Member of the Endocrine Society (and member of nominations committee)
  • Member of UKINETs and ENETs
  • Member of the British Menopause Society
  • Principal Fellow of the Higher Education Academy
  • Fellow of the Academy of Medical Educators

Key Publications

Full list of publications

Endocrinology

  1. Henderson JW, Montebello A, Grey J, Druce M. Frequency and impact of musculoskeletal symptoms on quality of life in MEN2B. Clin Endocrinol (Oxf) 2023 Feb;98(2):221-228.
  2. Papaioannou C, Druce M. Preoperative medical treatments and surgical approaches for acromegaly: A systematic review. Clin Endocrinol (Oxf). 2023 Jan;98(1):14-31.
  3. Goncharova M, Grey J, Druce M. Impact of gastrointestinal symptoms on quality of life in MEN2. Clin Endocrinol (Oxf). 2021 Apr;94(4):606-615
  4. Hussain Z, Glynn N, Martin M, Alkreshi A, Mendoza N, Nair R, McCullough K, Marcus HJ, Dorward N, Grieve J, Fersht N, Dyson N, Bouloux PM, Druce M*, Baldweg S* (*joint senior author). Temporal trends in craniopharyngioma management and long‐term endocrine outcomes: A multicentre cross‐sectional study. Clin Endocrinol (Oxf). 2021 Feb;94(2):242-249
  5. White BE, Druce MR, Grozinsky-Glasberg S, Srirajaskanthan R, Gamper EM, Gray D, Mujica-Mota R, Ramage JK. Health-related quality of life in neuroendocrine neoplasia: a critical review. Endocr Relat Cancer. 2020 Jul;27(7):R267-R280. doi: 10.1530/ERC-20-0066
  6. Lim ES, Shah SG, Waterhouse M, Akker S, Drake WM, Plowman PN, Berney DM, Richards P, Adams A, Nowosinska E, Brennan C, Druce M. Impact of thyroiditis on 131I uptake during ablative therapy for differentiated thyroid cancer. Endocrine Connections.(2019) May; 8(5): 571–578
  7. Ho W, Druce M. Quality of life in patients with adrenal disease: A systematic review. Clin Endocrinol (Oxf). 2018 Aug;89(2):119-128.
  8. Qureshi SA, Burch N, Druce M, Hattersley JG, Khan S, Gopalakrishnan K, Darby C, Wong JLH, Davies L, Fletcher S, Shatwell W, Sothi S,  Randeva HS, Dimitriadis GK, Weickert MO. Screening for malnutrition in patients with gastro-entero-pancreatic neuroendocrine tumours – a cross-sectional study. BMJ Open May 4;6(5):e010765. doi: 10.1136/bmjopen-2015-010765.
  9. Soh LM*, Druce MR*, Grossman A, Differ AM, Rajput L, Bitner-Glindzicz M, Korbonits M. Evaluation of genotype-phenotype relationships in patients referred for endocrine assessment in suspected Pendred syndrome. Eur J Endocrinol. 2015 Feb;172(2):217-26. *joint first authors
  10. Sze WCC, Grossman AB, Goddard I, Amendra D, Shieh SCC, Plowman PN, Drake WM, Akker SA and Druce MR. Sequelae and Survivorship in Patients Treated with 131I-MIBG Therapy. Br J Cancer 2013, Aug 6;109(3):565-72. doi: 10.1038/bjc.2013.365.
  11. Sen Gupta P, Grozinsky-Glasberg S, Drake WM et al. Are serotonin metabolite levels related to bone mineral density in patients with neuroendocrine tumours?. Clin Endocrinol (Oxf) 2014 Vol.80, (2) 246-252. 
  12. Druce MR, Walker D, Maher KT et al. (2011). The effect of exogenous glucocorticoids on plasma catecholamines and metanephrines in patients without phaeochromocytomas. Horm Metab Res 2011 Vol.43, (4) 292-295. 
  13. Druce MR, Muthuppalaniappan VM, O'Leary B et al. Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation. Eur J Endocrinol 2010 Vol.162, (5) 971-978. 10.1530/EJE-10-0056 

Teaching and Learning

  1. Druce MR, Howden S (2017) New perspectives on health professions students’ e-learning: looking through the lens of the ‘Visitor and Resident’ model. Medical Teacher. Jul;39(7):704-709.
  2. Druce MR, Hickey A, Warrens AW, Westwood O (2016) Medical Students Raising Concerns. Journal of Patient Safety. Accepted 
  3. Roff S, Druce MR, Livingston K, Roberts M, Stephenson A (2015) Mapping norms of professionalism within and between organisational cultures using the Dundee Polyprofessionalism Inventory I: Academic Integrity as an aid to proactive regulation. Journal of Medical Regulation 101 (3): 24-31 
  4. Druce M and Johnson MH (1994) Human Dissection and Attitudes of Preclinical Students to Death and Bereavement. Clinical Anatomy 7 : 42 - 49.

Collaborators

Internal

Dr Will Drake (WHRI); Prof Marta Korbonits (WHRI)

External

Ashley Grossman (Oxford); Simona Grozinsky (Jerusalem)

Teaching

  • Maralyn Druce initiated and is programme director for the Postgraduate Diploma / MSc programme in Endocrinology and Diabetes Mellitus. This is a highly popular and successful programme for higher trainees which uses novel distance learning methods. This programme won the e-learning age bronze award for ‘Best distance learning programme’ in 2014.
  • She initiated and is programme director for the campus-based MSc in Clinical Endocrinology.
  • She contributes to a number of aspects of the undergraduate teaching programme, both non-clinical and clinical, at Barts and the London School of Medicine, including special study components in Endocrinology.
  • She holds a number of roles in education management including Director of Academic Development at WHRI and Deputy Dean for Education within FMD.
  • She is Associate Dean for Undergraduates for the Barts site at Barts Health NHS Trust.
  • Within QMUL she has been awarded the William Harvey Prize for Teaching Excellence and the Drapers Award for excellence in teaching.
  • Externally she holds a Principal Fellowship of the Higher Education Academy.
  • She is a recipient of a National Teaching Fellowship Award from the HEA.

Disclosures

  • Professor Druce has previously received speaker fees and funding for conference attendance from Novartis and Ipsen.
  • Professor Druce is current Senior Editor for Clinical Endocrinology.
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