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The William Harvey Research Institute - Barts and The London

Professor Maralyn Druce

Maralyn

Professor of Endocrine Medicine

Centre: Endocrinology

Email: m.r.druce@qmul.ac.uk
Telephone: +44(0) 20 7882 8284

Profile

Professor Maralyn Druce undertook undergraduate training at Christ's College, Cambridge University and completed her clinical training at University College and Middlesex School of Medicine in 1994. She completed her higher medical training in Diabetes, Endocrinology and General Internal Medicine at the Hammersmith Hospital and Barts Hospital. She was awarded a Wellcome Trust clinical research training fellowship and obtained a PhD in physiology in Professor Steve Bloom's laboratory in Imperial College, focusing on gut hormones and their role in the peripheral and central control of energy homeostasis.

Maralyn went on to be awarded the Chadburn Lectureship at Barts and the London School of Medicine and has remained here since then. She has a keen interest in teaching and completed her Masters in Medical Education (Dundee) in 2016. She is now Professor of Endocrine Medicine and Consultant Physician and Endocrinologist at Barts Health NHS Trust.

Current QMUL roles include co-chair of the Athena Swan self-assessment team for the School of Medicine and Head of Governance for the Undergraduate MBBS and Dental programmes at Barts and the London.

She holds a number of external roles including Chair of the Society for Endocrinology Public Engagement Committee, Chair of the Education and Training Committee for UKINETs, member of the exam board for the Royal College of Physicians Diabetes and Endocrinology exam and Editor in Chief of Endocrinology, Diabetes and Metabolism Case Reports.

Research

Group members

Dr Triona O’Shea

Summary

Research interests include:

  • Pathophysiology, diagnosis and treatment of neuroendocrine tumours including fibrosis in the carcinoid syndrome, the use of targeted radionuclide therapy in the treatment of endocrine malignancy and the diagnosis and localisation of insulinoma. She is also involved in industry-sponsored clinical trials of novel pharmacological therapies
  • Factors affecting the production of catecholamines and metanephrines
  • Endocrine effects of cancer therapies
  • Gut hormones in the pathophysiology and treatment of obesity.

Memberships and awards

  • Fellow of the Royal College of Physicians
  • Senior Fellowship of the Higher Education Academy

Key Publications

For a full list of publications click here

Endocrinology

  • Qureshi SA, Burch N, Druce M, Hattersley JG, Khan S, Gopalakrishnan K, Darby C, Wong JLH,  Davies L, Fletcher S, Shatwell W, Sothi S,  Randeva HS, Dimitriadis GK, Weickert MO (2016) Screening for malnutrition in patients with gastro-entero-pancreatic neuroendocrine tumours – a cross-sectional study BMJ Open May 4;6(5):e010765. doi: 10.1136/bmjopen-2015-010765.
  • Soh LM*, Druce MR*, Grossman A, Differ AM, Rajput L, Bitner-Glindzicz M, Korbonits M Evaluation of genotype-phenotype relationships in patients referred for endocrine assessment in suspected Pendred syndrome. Eur J Endocrinol. 2015 Feb;172(2):217-26. *joint first authors
  • Sze WCC, Grossman AB, Goddard I, Amendra D, Shieh SCC, Plowman PN, Drake WM, Akker SA and Druce MR. (2013). Sequelae and Survivorship in Patients Treated with 131I-MIBG Therapy. Br J Cancer Aug 6;109(3):565-72. doi: 10.1038/bjc.2013.365.
  • Sen Gupta P, Grozinsky-Glasberg S, Drake WM et al. (2014). Are serotonin metabolite levels related to bone mineral density in patients with neuroendocrine tumours?. Clin Endocrinol (Oxf) Vol.80, (2) 246-252. 10.1111/cen.12270
  • Druce MR, Walker D, Maher KT et al. (2011). The effect of exogenous glucocorticoids on plasma catecholamines and metanephrines in patients without phaeochromocytomas.. Horm Metab Res Vol.43, (4) 292-295. 10.1055/s-0030-1270520
  • Druce MR, Muthuppalaniappan VM, O'Leary B et al. (2010). Diagnosis and localisation of insulinoma: the value of modern magnetic resonance imaging in conjunction with calcium stimulation catheterisation.. Eur J Endocrinol Vol.162, (5) 971-978. 10.1530/EJE-10-0056 
  • Druce MR, Minnion JS, Field BC et al. (2009). Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogues. Endocrinology Vol.150, (4) 0013-7227 1712-1722. 10.1210/en.2008-0828
  • Kaltsas G, Druce M & Grossman AB. Gastro-enteropancreatic (GEP) Tumors (2011) Translational Endocrinology & Metabolism: Endocrine Neoplasias – volume 2, number 4 The Endocrine Society
  • Druce MR, Lewington V, Grossman AB (2010). Targeted radionuclide therapy for neuroendocrine tumours: principles and application.. Neuroendocrinology Vol.91, (1) 1-15. 10.1159/000227808
  • Druce M, Rockall A, Grossman AB (2009). Fibrosis and carcinoid syndrome: from causation to future therapy. Nat Rev Endocrinol Vol.5, (5) 276-283. 10.1038/nrendo.2009.51

Teaching and Learning

  • Druce MR, Hickey A, Warrens AW, Westwood O (2016) Medical Students Raising Concerns. Journal of Patient Safety. Accepted 
  • Roff S, Druce MR, Livingston K, Roberts M, Stephenson A (2015) Mapping norms of professionalism within and between organisational cultures using the Dundee Polyprofessionalism Inventory I: Academic Integrity as an aid to proactive regulation. Journal of Medical Regulation 101 (3): 24-31 
  • Druce M and Johnson MH (1994) Human Dissection and Attitudes of Preclinical Students to Death and Bereavement. Clinical Anatomy 7 : 42 - 49.

Collaborators

Internal: Dr Will Drake (WHRI); Prof Marta Korbonits (WHRI).
External: Ashley Grossman (Oxford); Simona Grozinsky (Jerusalem).