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Professor Andreas Baumbach

Andreas

Chair for Device Innovation

Centre: Cardiovascular Medicine and Devices

Email: a.baumbach@qmul.ac.uk
Telephone: +44(0) 203 765 8740

Profile

He is active in coronary and structural intervention, and has published extensively in the field of interventional research covering preclinical, first in man, pivotal and post market studies. He has an interest in device innovation and regulatory pathways.

Professor Baumbach has a strong commitment to training and education. He is on the board of directors of the largest interventional congress EuroPCR and PCR London Valves. He Past President of the European Association of Percutaneous Cardiovascular Interventions (EAPCI).

Research

Group members

Prof Christos Bourantas; Dr Anantharam Ramasary; Dr Nida Ahmed; Dr Ratesh Bajaj; Dr Kush Patel

Summary

Active in first in human trials, as well as large scale multinational, multicentre randomised clinical trial evaluation of novel devices.

Key Publications

  1. Baumbach A, Patel KP, Kennon S, Ozkor M, Mathur A, Huerta F, Tamm AR. A heart valve dedicated for aortic regurgitation: Review of technology and early clinical experience with the transfemoral Trilogy system. Catheter Cardiovasc Interv. 2023 Aug 10. doi: 10.1002/ccd.30795. Epub ahead of print. PMID: 37560819.
  2. Kharbanda RK, Perkins AD, Kennedy J, Banning AP, Baumbach A, Blackman DJ, Dodd M, Evans R, Hildick-Smith D, Jamal Z, Ludman P, Palmer S, Stables R, Clayton T. Routine cerebral embolic protection in transcatheter aortic valve implantation: rationale and design of the randomised British Heart Foundation. PROTECT-TAVI trial. EuroIntervention. 2023 Apr 24;18(17):1428-1435. doi: 10.4244/EIJ-D-22-00713. PMID: 36706009; PMCID: PMC10111121.
  3. Patel KP, Baumbach A. Future of transcatheter aortic valve implantation: where do we go from here? Heart. 2023 Mar 10;109(7):564-571. doi: 10.1136/heartjnl-2022-321575. PMID: 36631145.
  4. Task Force for the management of COVID-19 of the European Society of Cardiology. European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1-epidemiology, pathophysiology, and diagnosis. Eur Heart J. 2022 Mar 14;43(11):1033-1058. doi: 10.1093/eurheartj/ehab696. Erratum in: Eur Heart J. 2021 Dec 20;: PMID: 34791157; PMCID: PMC8690026.
  5. Patel KP, Michail M, Treibel TA, Rathod K, Jones DA, Ozkor M, Kennon S, Forrest JK, Mathur A, Mullen MJ, Lansky A, Baumbach A. Coronary Revascularization in Patients Undergoing Aortic Valve Replacement for Severe Aortic Stenosis. JACC Cardiovasc Interv. 2021 Oct 11;14(19):2083-2096. doi: 10.1016/j.jcin.2021.07.058. PMID: 34620388.
  6. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Coats AJS, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Francesco Piepoli M, Price S, Rosano GMC, Ruschitzka F, Kathrine Skibelund A; ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021 Sep 21;42(36):3599-3726. doi: 10.1093/eurheartj/ehab368. Erratum in: Eur Heart J. 2021 Oct 14;: PMID: 34447992.
  7. Candiello A, Alexander T, Delport R, Toth GG, Ong P, Snyders A, Belardi JA, Lee MKY, Pereira H, Mohamed A, Mayol J, Piek JJ, Wijns W, Baumbach A, Naber C. How to set up regional STEMI networks: a "Stent - Save a life!" initiative. EuroIntervention. 2022 Mar 18;17(16):1313-1317. doi: 10.4244/EIJ-D-21-00694. PMID: 34387547; PMCID: PMC9743232.
  8. Lansky AJ, Makkar R, Nazif T, Messé S, Forrest J, Sharma R, Schofer J, Linke A, Brown D, Dhoble A, Horwitz P, Zang M, DeMarco F, Rajagopal V, Dwyer MG, Zivadinov R, Stella P, Rovin J, Parise H, Kodali S, Baumbach A, Moses J. A randomized evaluation of the TriGuard™ HDH cerebral embolic protection device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic Valve ImplanTation: the REFLECT I trial. Eur Heart J. 2021 Jul 15;42(27):2670-2679. doi: 10.1093/eurheartj/ehab213. PMID: 34000004.
  9. Coats AJS, Anker SD, Baumbach A, Alfieri O, von Bardeleben RS, Bauersachs J, Bax JJ, Boveda S, Čelutkienė J, Cleland JG, Dagres N, Deneke T, Farmakis D, Filippatos G, Hausleiter J, Hindricks G, Jankowska EA, Lainscak M, Leclercq C, Lund LH, McDonagh T, Mehra MR, Metra M, Mewton N, Mueller C, Mullens W, Muneretto C, Obadia JF, Ponikowski P, Praz F, Rudolph V, Ruschitzka F, Vahanian A, Windecker S, Zamorano JL, Edvardsen T, Heidbuchel H, Seferovic PM, Prendergast B. The management of secondary mitral regurgitation in patients with heart failure: a joint position statement from the Heart Failure Association (HFA), European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA), and European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. Eur Heart J. 2021 Mar 31;42(13):1254-1269. doi: 10.1093/eurheartj/ehab086. PMID: 33734354; PMCID: PMC8014526.
  10. Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, Prescott E, Karam N, Appelman Y, Fraccaro C, Louise Buchanan G, Manzo-Silberman S, Al-Lamee R, Regar E, Lansky A, Abbott JD, Badimon L, Duncker DJ, Mehran R, Capodanno D, Baumbach A. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in Collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. Eur Heart J. 2020 Oct 1;41(37):3504-3520. doi: 10.1093/eurheartj/ehaa503. PMID: 32626906; PMCID: PMC7577516.
  11. Räber L, Yamaji K, Kelbæk H, Engstrøm T, Baumbach A, Roffi M, von Birgelen C, Taniwaki M, Moschovitis A, Zaugg S, Ostojic M, Pedrazzini G, Karagiannis- Voules DA, Lüscher TF, Kornowski R, Tüller D, Vukcevic V, Heg D, Windecker S. Five-year clinical outcomes and intracoronary imaging findings of the COMFORTABLE AMI trial: randomized comparison of biodegradable polymer-based biolimus-eluting stents with bare-metal stents in patients with acute ST-segment elevation myocardial infarction. Eur Heart J. 2019 Jun 21;40(24):1909-1919. doi: 10.1093/eurheartj/ehz074. PMID: 30851032.
  12. Baumbach A, Lansky AJ, Onuma Y, Asano T, Johnson T, Anderson R, Kiemeneij F, Zheng M, Van Royen N, Slagboom T, Vlachojannis G, Xu B, Serruys PW, Wijns W. Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic lesions: TARGET All Comers. EuroIntervention. 2018 Nov 20;14(10):1121-1128. doi: 10.4244/EIJ-D-18-00226. PMID: 29901441.
  13. Cortese B, Montefusco A, D'Ascenzo F, La Manna A, Andò G, Bisceglia T, Secco GG, Meyer-Gessner M, Wańha W, Sganzerla P, Napodano M, Di Palma G, Latini RA, Tamburino C, Orrego PS, Baumbach A. Clinical performance of a dedicated self- apposing stent for the treatment of left main stem disease. Results of the left Main AngioplasTy wIth a Self-apposing StEnt - the MATISSE study. Cardiovasc Revasc Med. 2018 Oct-Nov;19(7 Pt B):831-836. doi: 10.1016/j.carrev.2018.03.005. Epub 2018 Apr 4. PMID: 29661597.
  14. Baumbach A, Zaman A, West NEJ, O'Kane P, Egred M, Johnson T, Wheatcroft S, Bowles R, de Belder A, Bouras G, Lansky A, Hill J, Mathur A, de Belder MA, Banning AP. Acute and one-year clinical outcomes following implantation of bioresorbable vascular scaffolds: the ABSORB UK Registry. EuroIntervention. 2018 Jan 20;13(13):1554-1560. doi: 10.4244/EIJ-D-17-00886. PMID: 29131802.
  15. Lansky AJ, Messé SR, Brickman AM, Dwyer M, van der Worp HB, Lazar RM, Pietras CG, Abrams KJ, McFadden E, Petersen NH, Browndyke J, Prendergast B, Ng VG, Cutlip DE, Kapadia S, Krucoff MW, Linke A, Moy CS, Schofer J, van Es GA, Virmani R, Popma J, Parides MK, Kodali S, Bilello M, Zivadinov R, Akar J, Furie KL, Gress D, Voros S, Moses J, Greer D, Forrest JK, Holmes D, Kappetein AP, Mack M, Baumbach A. Proposed Standardized Neurological Endpoints for Cardiovascular Clinical Trials: An Academic Research Consortium Initiative. J Am Coll Cardiol. 2017 Feb 14;69(6):679-691. doi: 10.1016/j.jacc.2016.11.045. PMID: 28183511.
  16. Lansky A, Wijns W, Xu B, Kelbæk H, van Royen N, Zheng M, Morel MA, Knaapen P, Slagboom T, Johnson TW, Vlachojannis G, Arkenbout KE, Holmvang L, Janssens L, Ochala A, Brugaletta S, Naber CK, Anderson R, Rittger H, Berti S, Barbato E, Toth GG, Maillard L, Valina C, Buszman P, Thiele H, Schächinger V, Baumbach A; TARGET All Comers Investigators. Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre, open-label, randomised non-inferiority trial. Lancet. 2018 Sep 29;392(10153):1117-1126. doi: 10.1016/S0140-6736(18)31649-0. Epub 2018 Sep 3. PMID: 30190206.

Collaborators

External

  • Meril Life
  • Jenavalve
  • Microport

Disclosures

  • Institutional Research Support from Abbott Vascular
  • Consultation and Speaker Fees from Astra Zeneca, Sinomed, Microport, Medtronic, Faraday Pi-Cardia, Biosensors, Jenavalve
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