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Blizard Institute - Faculty of Medicine and Dentistry

Dr Laura Green, MBBS, FRCP, FRCPath, MD(Res)

Laura

Clinical Reader in Transfusion Medicine; Consultant in Haemostasis and Transfusion Medicine

Centre: Centre for Neuroscience, Surgery and Trauma

Email: laura.green@qmul.ac.uk
Telephone: +44 7720275360
Twitter: @LGreenBartsNHS

Profile

ORCHID iD: 0000-0003-4063-9768

Dr Green entered the specialist training in Haematology at Kings College Hospital, London in 2004. She went on to undertake research in Haemostasis and Thrombosis at University College London, leading to the degree of MD(Res). In 2011 she was appointed a Consultant in Haemostasis and Transfusion Medicine, with joint appointments at NHS Blood and Transplant (NHSBT) and Barts Health Trust. In 2018 she was appointed a Senior Clinical Lecturer in Transfusion Research and Innovation at Queen Mary University of London and was promoted to Reader in 2022. In 2020 she became a Principal Investigator at NHSBT. Dr Green’s clinical duties are based at NHSBT and Barts Health Trust where she provides leadership on the appropriate use of blood components. In 2021 she was appointed Clinical Lead for Blood Transfusion for the South East London Pathology Partnership, covering seven transfusion laboratories. 

Research

Research Interests:

Dr Green’s research remit focuses on improving the treatment of acquired bleeding disorders (e.g. trauma, obstetrics, cardiac etc) and bridging laboratory research and clinical work by developing new blood component that can improve the outcome of bleeding patients. She has led numerous randomised control trials, nationals epidemiological studies and systematic reviews in the field of acquired bleeding disorders.

Publications

Key Publications

Cardigan R, Latham T, Weaver A, Yazer M, Green L (2022). Estimating the risks of prehospital transfusion of D-positive whole blood to trauma patients who are bleeding in England. Vox Sang 10.1111/vox.13249

Green L, Daru J, Gonzalez Carreras FJ, Lanz D, Pardo MDC, Perez T, Philip S, Tanqueray T et al. (2022). Early cryoprecipitate transfusion versus standard care in severe postpartum haemorrhage: a pilot cluster-randomised trial. Anaesthesia, 77 (2), 175-184.

Green L, Roberts N, Cooper J, Agarwal S, Brunskill SJ, Chang I, Gill R, Johnston A et al. (2021). Prothrombin complex concentrate vs. fresh frozen plasma in adult patients undergoing heart surgery – a pilot randomised controlled trial (PROPHESY trial). Anaesthesia vol. 76, (7) 892 - 901.

Green L, Tan J, Morris JK, Alikhan R, Curry N, Everington T, Mclean R, Saja K, Stanworth S, Tait C, MacCallum P. A three-year prospective study of the presentation and clinical outcomes of major bleeding episodes associated with oral anticoagulant use in the UK (ORANGE study). Haematologica. 2018 Apr;103(4):738-745

Green L, Knight M, Seeney FM, Hopkinson C, Collins PW, Collis RE, Simpson NAB, Weeks A et al. (2016). The epidemiology and outcomes of women with postpartum haemorrhage requiring massive transfusion with eight or more units of red cells: A national cross‐sectional study. BJOG: vol. 123, (13) 2164 – 2170.

All Publications

Supervision

Dr Green is supervising several PhD/MD students - a common research theme of their research is better understanding of current transfusion management of bleeding and their coagulation abnormalities, with a view to testing targeted interventions through future trials.

Ongoing students

  • Dr H. Tucker. PhD (2019 – 2022) – first supervisor
  • Ms J. McCullagh. PhD (2018 - 2022) – first supervisor
  • Dr A. Rossetto. PhD (2019 – 2022) – second supervisor
  • Ms Florence Oyekan (2022 – 2025) – first supervisor 

Completed

  • Dr R. Kohli. MD (completed December 2021) - second supervisor
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