We are recruiting people with asthma to take part in our study. Read more and sign up below
IONA Study Study information IONA Study Team Study Protocol Science and News
Due to the increased weight of electric and hybrid vehicles, they produce more non-exhaust pollution from brake, tyre, and road wear. To date, no research has explored the health impacts of non-exhaust air pollution on human health in real world settings.
IONA is a research study that looks at how different air pollution environments impact the health of people living with asthma.
You can participate if you are an adult who was diagnosed with asthma on or before the age of 16, have a prescription for regular inhaled corticosteroid medication, and are able to use a static exercise bicycle.
You cannot participate if you are pregnant, breastfeeding, smoke tobacco or live with someone who smokes, have a BMI over 30, have been hospitalised for asthma within the last 12 months, have had chest surgery within the last 6 months, or have any other major lung disease. People who work as taxi drivers, couriers, waste removal drivers, or utility service drivers are also not able to participate in this study.
Please click to download our Participant information sheet [PDF 230KB]
Queen Mary Ethics of Research Committee reference number: QMERC22.170
IONA is a research study to find out how different air pollution environments impact markers of health in people living with asthma. Specifically, we are interested in how lung function changes immediately following exercise in air pollution. We will also study respiratory symptoms (like wheezing, sneezing, coughing) and ask to collect blood and nasal mucus samples for further air pollution based analysis.
This document will explain why the research is being done and what it will involve. Please take time to read the following information carefully and discuss it with others if you wish. You do not need to provide a reason if you do not wish to participate and it will not affect your rights or your care. Please ask the research team if you would like more information.
This study is led by Queen Mary University London (QMUL) in collaboration with Imperial College London. QMUL is the study sponsor.
What is the purpose of the study?
What would taking part involve?
Image of exercise bikes at Marylebone testing site
Why am I being invited?
Do I have to take part?
No, it is up to you to decide whether or not to take part. If you decide to take part, you will need to sign the consent form and return it to the research team. You can stop taking part in some parts of this study, or all of it, at any time and without giving a reason. If you do decide to take part you will be free to withdraw at any time without needing to provide a reason, and with no penalties or detrimental effects.
Optional sample storage:
What are the possible benefits of taking part?
What are the possible disadvantages and risks of taking part?
Expenses and payments
How will we use information about you?
We will need to use information about you for this research project. This information will include your:
People will use this information to make sure that the research is being done properly. People who do not need to know who you are will not be able to see your name or contact details. Your data will have a code number instead. We will keep all information about you safe and secure.
Once we have finished the study, we will keep some of the data so we can check the results. We will write our reports in a way that no one can work out that you took part in the study.
See also: http://www.arcs.qmul.ac.uk/media/arcs/policyzone/Privacy-Notice-for-Research-Participants.pdf
How will my data be stored and who will have access to it?
Any information we collect from you will be transferred to, stored and analysed secure servers of Queen Mary University of London. Your data will be stored in de-identified format, your name and other identifiers will be replaced by a unique code to reduce the risk of disclosure, personal identifiers will be stored separately from the research data on secure computers. Paper records of data (e.g. consent forms) will be stored either in locked filing cabinets within lockable offices within an access restricted building, or will be sent off site to a secure storage facility that complies with our security requirements. All data handling, processing, transfer and storage procedures comply with our obligations under the General Data Protection Regulation, and comply with our local data handling and security policies and procedures. Personal data will only be accessed and used by those members of the research team at QMUL and representatives of the sponsor who have been granted permission.
When and how will my data be destroyed?
How will my data be used and shared?
How will my samples be used?
What will happen if I want to withdraw from this study?
What should I do if I have concerns or something goes wrong during this study?
Who can I contact if I have any questions about this study?
Please click to download our IONA Consent form V4.0 12.04.2023 [PDF 128KB]
Thank you for your interest in this research.
Should you wish to participate in the study, please consider the statements in the link about. Before signing the consent form, you should initial all or any of the statements that you agree with. Your signature confirms that you are willing to participate in this research, however you are reminded that you are free to withdraw your participation at any time.
Chief investigator: Dr James Scales
To express an interest in taking part or to ask any questions about the study email Dr James Scales at J.email@example.com