Acute Kidney Injury (AKI) is a frequent complication of critical illness, major surgery and acute medical admissions that has been independently associated with other complications, prolonged length of stay and in-hospital mortality.
Survivors of even mild AKI have increased risk of death, development of chronic kidney disease, end stage renal disease and cardiovascular complications in the longer term.
Dr John Prowle leads the interdisciplinary critical care nephrology research group. The team focus on innovation across the spectrum of AKI research including clinical and translational research, computational modelling, precision and predictive analytics, and health care delivery. Dr Prowle is also a member of the department of Renal and Transplantation medicine and collaborates with colleagues in renal, acute medicine, trauma surgery and peri-operative medicine on AKI research.
Nationally, Dr Prowle is an active senior participant in the UK AKI Clinical Studies Group and internationally in the Acute Dialysis Quality Initiative and the Kidney Disease Improving Global Outcomes AKI work stream.
Major research domains include:
Ongoing and recent projects:
The group has a portfolio of industry sponsored research and collaborations.