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The William Harvey Research Institute - Faculty of Medicine and Dentistry

Professor Charles Knight


Professor of Cardiology

Centre: CV Medicine and Devices

Twitter: @mdstbarts


Professor Charles Knight trained at Cambridge and Oxford Universities and is Chief Executive and Consultant Cardiologist at St Bartholomew’s Hospital (Barts Health NHS Trust). He is an honorary Professor at the William Harvey Research Institute, Queen Mary University of London. He has served as Honorary Secretary of the British Cardiovascular Society, Associate Editor of Heart and Chair of the London Cardiology Specialty Training Committee. He was a member of the Cardiology SAC and the BCS training committee.


  • Acute Coronary Syndromes
  • Cardio-renal disease
  • Hypertrophic cardiomyopathy (septal ablation)

Key Publications

  • Knight CJ, Kurbaan A, Seggewiss H, Henein M, Gunning M, Harrington D, Fassbender D, Gleichmann U,  Sigwart U.   Non-surgical septal reduction for hypertrophic obstructive cardiomyopathy: outcome in the first series of patients. Circulation 1997;95:2075-2081.
  • Baker CS, Wragg A, Kumar S, De Palma R, Baker LR, Knight CJ.  A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study.  Journal of the American College of Cardiology 2003;18:2114-8.
  • Graham JJ, Timmis AD, Cooper J, Ramdany S, Deaner A, Ranjadayalan K, Knight C. The impact of the National Service Framework for Coronary Artery Disease on treatment and outcome of patients with acute coronary syndromes.
  • Campbell NG, Varagunam M, Sawhney V, Ahuja KR, Salahuddin N, De Palma R, Rothman MT, Wragg A, Yaqoob MM, Knight CJ. Mild chronic kidney disease is an independent predictor of long-term mortality after emergency angiography and primary percutaneous intervention in patients with ST-segment elevation myocardial infarction (STEMI). Heart 2012;98:42-7.
  • Rathod KS, Jones DA, Gallagher SM, Bromage DI,  Whitbread M, Archbold AR, Jain AK, Mathur A, Wragg A, Knight CJ . Out of hours Primary Percutaneous Coronary Intervention for ST-elevation myocardial infarction is not associated with excess mortality. A study of 3347 patients treated in an integrated cardiac network. BMJ Open 2013;3:e003063 doi:10.1136/bmjopen-2013-003063




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