Professor Alastair Noyce, BMedSci, MB BS, MSc, MRCP, PhD, FHEAProfessor in Neurology and Neuroepidemiology and Consultant NeurologistEmail: a.noyce@qmul.ac.ukProfileResearchPublicationsSupervisionProfileI am the Professor in Neurology and Neuroepidemiology in the Centre for Preventive, Detection and Diagnosis (CPDD), in the Wolfson Institute of Population Health, Queen Mary University of London (QMUL). I am the Lead of the Preventive Neurology Unit (PNU) based within CPDD and a Consultant Neurologist at Barts Health NHS Trust. I graduated from Barts and the London (QMUL) in 2007 and I pursued integrated training via the Foundation Academic Programme and an NIHR Academic Clinical Fellowship at UCL. Between 2012-2016 I undertook a PhD in Neuroscience at UCL and between 2014-2016 I undertook an MSc in Epidemiology at London School of Hygiene and Tropical Medicine. I re-joined QMUL and the PNU in 2017 to lead the Parkinson’s programme of work. My research interests are Parkinson’s disease and other neurodegenerative disorders, particularly early identification and epidemiological aspects, including environmental, clinical and genetic determinants. I am the co-principal investigator of the PREDICT-PD study, principal investigator for the East London Parkinson’s Disease project and chief investigator for the Access-PD study. I am a member of the International Parkinson and Movement Disorder Society (MDS). I graduated from the MDS LEAP leadership programme in 2020, and then became a member of the faculty for the LEAP, teaching leadership skills to early career movement disorders specialists around the world. I am the Chair of the MDS Epidemiology Study Group, a member of the MDS Early Onset PD Task Force, and sit on the MDS Prodromal Parkinson’s Subcommittee. I also sit on the Executive Steering Committee of the Global Parkinson’s Genetics Program (GP2) and lead one of its working groups, focusing on Training and Networking. I am the Chair of the Think Brain Health Global initiative and Associate Editor for the Journal of Parkinson’s Disease. Away from neurodegenerative disease, I am interested in the emerging link between recreational use of nitrous oxide (laughing gas) and neurological harm. I am a member of the Advisory Council for the Misuse of Drugs, who are advising the government on this matter. I have led the drafting of national guidance for managing the range of neurological conditions associated with nitrous oxide, as well as describing the clinical manifestations in patients in order to raise awareness amongst healthcare workers.ResearchResearch Interests:Neurology Epidemiology Genetics Predictive models Clinical researchPublications Leonard HL, Murtadha R, Martinez-Carrasco A et al. (2023). The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data. nameOfConference DOI: 10.1038/s41531-023-00472-6 QMRO: qmroHref Nagy AV, Leschziner G, Eriksson SH et al. (2023). Cognitive impairment in REM-sleep behaviour disorder and individuals at risk of Parkinson's disease. nameOfConference DOI: 10.1016/j.parkreldis.2023.105312 QMRO: qmroHref Frisoni GB, Altomare D, Ribaldi F et al. (2023). Dementia prevention in memory clinics: recommendations from the European task force for brain health services. nameOfConference DOI: 10.1016/j.lanepe.2022.100576 QMRO: qmroHref Foltynie T, Gandhi S, Gonzalez-Robles C et al. (2023). Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson's disease.. nameOfConference DOI: 10.1093/brain/awad063 QMRO: qmroHref Paris A, Lake L, Joseph A et al. (2023). Nitrous oxide-induced subacute combined degeneration of the cord: diagnosis and treatment.. nameOfConference DOI: 10.1136/pn-2022-003631 QMRO: qmroHref Zirra A, Rao SC, Bestwick J et al. (2023). Gender Differences in the Prevalence of Parkinson's Disease. nameOfConference DOI: 10.1002/mdc3.13584 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/82482 Bramich S, Verdi K, Salmon K et al. (2023). REM sleep behaviour disorder: the importance of early identification in primary care. nameOfConference DOI: 10.3399/bjgp23X731721 QMRO: qmroHref Noyce A (2022). The association between anti-epileptic drugs and incident Parkinson’s disease in UK Biobank. nameOfConference DOI: 10.1001/jamaneurol.2022.4699 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/82500 Krohn L, Heilbron K, Blauwendraat C et al. (2022). Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. nameOfConference DOI: 10.1038/s41467-022-34732-5 QMRO: qmroHref Dadu A, Satone V, Kaur R et al. (2022). Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts. nameOfConference DOI: 10.1038/s41531-022-00439-z QMRO: qmroHref Periñán MT, Brolin K, Bandres-Ciga S et al. (2022). Effect Modification between Genes and Environment and Parkinson's Disease Risk. nameOfConference DOI: 10.1002/ana.26467 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80493 Jacobs BM, Peter M, Giovannoni G et al. (2022). Towards a global view of multiple sclerosis genetics. nameOfConference DOI: 10.1038/s41582-022-00704-y QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80522 Hone L, Jacobs BM, Marshall C et al. (2022). Age-specific effects of childhood body mass index on multiple sclerosis risk. nameOfConference DOI: 10.1007/s00415-022-11161-4 QMRO: qmroHref Bramich S, King A, Kuruvilla M et al. (2022). Isolated REM sleep behaviour disorder: current diagnostic procedures and emerging new technologies. nameOfConference DOI: 10.1007/s00415-022-11213-9 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/78951 Foote IF, Jacobs BM, Mathlin G et al. (2022). The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study. nameOfConference DOI: 10.1016/j.neurobiolaging.2022.02.016 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/79699 Liu H, Dehestani M, Blauwendraat C et al. (2022). Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors. nameOfConference DOI: 10.1002/ana.26416 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/79159 Schumacher-Schuh AF, Bieger A, Okunoye O et al. (2022). Underrepresented Populations in Parkinson's Genetics Research: Current Landscape and Future Directions. nameOfConference DOI: 10.1002/mds.29126 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/78952 Simonet C, Bestwick J, Jitlal M et al. (2022). Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population. nameOfConference DOI: 10.1001/jamaneurol.2022.0003 QMRO: qmroHref Marshall CR, Noyce AJ, Neligan A et al. (2022). Brain health: The hidden casualty of a humanitarian crisis. nameOfConference DOI: 10.1016/j.lanepe.2022.100374 QMRO: qmroHref Bothongo PLK, Jitlal M, Parry E et al. (2022). Dementia risk in a diverse population: A single-region nested case-control study in the East End of London. nameOfConference DOI: 10.1016/j.lanepe.2022.100321 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75791 Noyce A (2022). No evidence for association between polygenic risk of Multiple Sclerosis and MRI phenotypes in ~30,000 healthy adult UK Biobank participants. nameOfConference DOI: 10.1177/2F13524585221075744 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/76333 Noyce A (2022). Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population. nameOfConference DOI: 10.1001/jamaneurol.2022.0003 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75666 Cornejo-Olivas M, Wu L, Noyce A (2022). Disruption of Mitochondrial Complex I Induces Progressive Parkinsonism. nameOfConference DOI: 10.1002/mds.28961 QMRO: qmroHref Noyce A (2022). Surveying global availability of Parkinson’s disease treatment. nameOfConference DOI: 10.3233/JPD-213006 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/76599 Noyce A (2022). The potential utility of smell testing to screen for neurodegenerative disorders. nameOfConference DOI: 10.1080/14737159.2022.2037424 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/76598 Huxford B, Haque T, Joseph AB et al. (2022). Parkinson's Disease and Type 2 Diabetes: HbA1c Is Associated with Motor and Cognitive Severity. nameOfConference DOI: 10.1002/mds.28829 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74651 Dobson R, Marshall C, Noyce A (2022). Social determinants of neurological disease: tackling inequalities. nameOfConference DOI: 10.1016/S1474-4422(22)00005-9 QMRO: qmroHref Noyce A (2022). Developing and Assessing a New Web-based Tapping Test for Measuring Distal Movement in Parkinson’s Disease: a Distal Finger Tapping Test. nameOfConference DOI: 10.1038/s41598-021-03563-7 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75667 Mitchell E, Chohan H, Bestwick JP et al. (2022). Alcohol and Parkinson's Disease: A Systematic Review and Meta-Analysis. nameOfConference DOI: 10.3233/JPD-223522 QMRO: qmroHref Day JO, Smith S, Noyce AJ et al. (2022). Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT. nameOfConference DOI: 10.3233/JPD-223162 QMRO: qmroHref Kent DM, Leung LY, Puttock EJ et al. (2022). Development of Parkinson Disease and Its Relationship with Incidentally Discovered White Matter Disease and Covert Brain Infarction in a Real-World Cohort. nameOfConference DOI: 10.1002/ana.26458 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/80538 Storm CS, Kia DA, Almramhi MM et al. (2021). Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome. nameOfConference DOI: 10.1038/s41467-021-26280-1 QMRO: qmroHref Chen Z, Zhang D, Reynolds RH et al. (2021). Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage. nameOfConference DOI: 10.1038/s41467-021-22262-5 QMRO: qmroHref Gialluisi A, Reccia MG, Modugno N et al. (2021). Identification of sixteen novel candidate genes for late onset Parkinson’s disease. nameOfConference DOI: 10.1186/s13024-021-00455-2 QMRO: qmroHref Bestwick JP, Auger SD, Simonet C et al. (2021). Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm. nameOfConference DOI: 10.1038/s41531-021-00176-9 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68734 Hone L, Jacobs B, Noyce A et al. (2021). Age-specific effects of childhood BMI on multiple sclerosis risk: a Mendelian Randomisation study. nameOfConference DOI: doi QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/75629 Bestwick J, Auger S, Schrag A et al. (2021). Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features. nameOfConference DOI: 10.1038/s41531-021-00226-2 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/73808 Hone L, Jacobs B, Marshall C et al. (2021). Age-specific effects of childhood Body Mass Index on multiple sclerosis risk. nameOfConference DOI: 10.1101/2021.09.12.21263445 QMRO: qmroHref Noyce A, Beccano-Kelly D, Bandres-Ciga S et al. (2021). Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunities. nameOfConference DOI: 10.36866/123.32 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/74653 Estiar MA, Senkevich K, Yu E et al. (2021). Lack of Causal Effects or Genetic Correlation between Restless Legs Syndrome and Parkinson's Disease. nameOfConference DOI: 10.1002/mds.28640 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/71705 Bandres-Ciga S, Saez-Atienzar S, Kim JJ et al. (2021). Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease (Acta Neuropathologica, (2020), 140, 3, (341-358), 10.1007/s00401-020-02181-3). nameOfConference DOI: 10.1007/s00401-021-02309-z QMRO: qmroHref Jacobs BM, Noyce AJ, Bestwick J et al. (2021). Gene-Environment Interactions in Multiple Sclerosis: A UK Biobank Study. nameOfConference DOI: 10.1212/NXI.0000000000001007 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70963 Blauwendraat C, Iwaki H, Makarious MB et al. (2021). Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease. nameOfConference DOI: 10.1002/ana.26090 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/71700 Jacobs BM, Smets I, Giovannoni G et al. (2021). Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis. nameOfConference DOI: 10.1177/1352458520969941 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/69385 Simonet C, Noyce A (2021). Mild parkinsonian signs: the interface between aging and Parkinson’s disease. nameOfConference DOI: 10.47795/khgp5988 QMRO: qmroHref Simonet C, Schrag A, Lees AJ et al. (2021). The motor prodromes of parkinson’s disease: from bedside observation to large-scale application. nameOfConference DOI: 10.1007/s00415-019-09642-0 QMRO: qmroHref Chohan H, Senkevich K, Patel RK et al. (2021). Type 2 Diabetes as a Determinant of Parkinson's Disease Risk and Progression. nameOfConference DOI: 10.1002/mds.28551 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70848 Ismail AS, Goodwin GR, Castrejon-Pita JR et al. (2021). A novel capsule-based smell test fabricated via coaxial dripping. nameOfConference DOI: 10.1098/rsif.2021.0039 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/71695 Global Parkinson's Genetics Program (2021). GP2: The Global Parkinson's Genetics Program.. nameOfConference DOI: 10.1002/mds.28494 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70356 Bestwick JP, Auger SD, Simonet C et al. (2021). Improving estimation of Parkinson's disease risk-the enhanced PREDICT-PD algorithm.. nameOfConference DOI: 10.1038/s41531-021-00176-9 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/71965 Jensen MP, Jacobs BM, Dobson R et al. (2021). Lower Lymphocyte Count is Associated With Increased Risk of Parkinson's Disease. nameOfConference DOI: 10.1002/ana.26034 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70059 Jitlal M, Amirthalingam G, Karania T et al. (publicationYear). The influence of socioeconomic deprivation on dementia mortality, age at death and quality of diagnosis: a nationwide death records study in England and Wales 2001-2017. nameOfConference DOI: 10.3233/JAD-210089 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70919 Foote I, Jacobs B, Mathlin G et al. (2021). The Genetic Architecture of Alzheimer’s Disease Risk: A Genomic Structural Equation Modelling Study. nameOfConference DOI: 10.1101/2021.02.23.21252211 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/72648 Kang X, Ploner A, Pedersen N et al. (2021). Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study. nameOfConference DOI: 10.1212/WNL.0000000000011630 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/69397 Noyce A (2021). Infection and Risk of Parkinson’s disease. nameOfConference DOI: 10.3233/JPD-202279 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68810 Simonet C, Noyce AJ (2021). Domotics, Smart Homes, and Parkinson's Disease. nameOfConference DOI: 10.3233/JPD-202398 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70669 Noyce AJ, Klein C (2021). Genetic Risk of Alzheimer's Disease – Sleepless with the Enemy. nameOfConference DOI: 10.1002/ana.25938 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68509 Senkevich K, Bandres-Ciga S, Yu E et al. (2021). No Evidence for a Causal Relationship between Cancers and Parkinson's Disease. nameOfConference DOI: 10.3233/JPD-202474 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70670 Simonet C, Galmes MA, Lambert C et al. (2021). Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson's Disease and Idiopathic Anosmia. nameOfConference DOI: 10.3233/jpd-212683 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/72405 Heilbron K, Jensen MP, Bandres-Ciga S et al. (2021). Unhealthy Behaviours and Risk of Parkinson's Disease: A Mendelian Randomisation Study. nameOfConference DOI: 10.3233/jpd-202487 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/73518 Blauwendraat C, Makarious MB, Leonard HL et al. (publicationYear). A population scale analysis of rare SNCA variation in the UK Biobank. nameOfConference DOI: 10.1016/j.nbd.2020.105182 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68806 Foote IF, Jacobs BM, Noyce AJ et al. (2020). Exploring the shared genetic architecture of modifiable risk factors and related endophenotypes of Alzheimer’s disease: A genomic SEM study. nameOfConference DOI: 10.1002/alz.045164 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/70959 Guelfi S, D’Sa K, Botía JA et al. (2020). Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information. nameOfConference DOI: 10.1038/s41467-020-14483-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/66523 Iwaki H, Blauwendraat C, Leonard HL et al. (2020). Differences in the Presentation and Progression of Parkinson's Disease by Sex. nameOfConference DOI: 10.1002/mds.28312 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/68641 Auger SD, Jacobs BM, Dobson R et al. (2020). Big data, machine learning and artificial intelligence: a neurologist's guide.. nameOfConference DOI: 10.1136/practneurol-2020-002688 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/67605 Auger S, Jacobs B, Dobson R et al. (2020). Navigating a world of big data, machine learning and artificial intelligence: a neurologist's guide. nameOfConference DOI: 10.1136/practneurol-2020-002688 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/67242 Jacobs B, Belete D, Bestwick J et al. (2020). Parkinson’s disease determinants, prediction and gene-environment interactions in the UK Biobank. nameOfConference DOI: 10.1136/jnnp-2020-323646 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/66809 Mencacci NE, Reynolds R, Ruiz SG et al. (2020). Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders. nameOfConference DOI: 10.1093/brain/awaa217 QMRO: qmroHref Cheong J, Goh Z, Marras C et al. (2020). The impact of COVID-19 on access to Parkinson’s disease medication. nameOfConference DOI: 10.1002/mds.28293 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/66849 Noyce A (publicationYear). Evaluating lipid-lowering drug targets for Parkinson’s disease prevention with Mendelian randomization. nameOfConference DOI: 10.1002/ana.25880 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/66846 Jacobs B, Taylor T, Awad A et al. (2020). Summary-data-based mendelian randomisation prioritises potential druggable targets for Multiple Sclerosis. nameOfConference DOI: 10.1093/braincomms/fcaa119 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/65644 Noyce A (2020). Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease. nameOfConference DOI: 10.1007/s00401-020-02181-3 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/65756 Marini K, Mahlknecht P, Tutzer F et al. (publicationYear). Application of a Simple Parkinson's Disease Risk Score in a Longitudinal Population‐Based Cohort. nameOfConference DOI: 10.1002/mds.28127 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/65120 Noyce A, Giovannoni G, Scheltens P et al. (2020). Time matters in brain health: how should society prepare for a growing population at risk of neurodegenerative diseases?. nameOfConference DOI: doi QMRO: qmroHref Cheong J, de Pablo-Fernandez E, Foltynie T et al. (publicationYear). The association between type 2 diabetes mellitus and Parkinson’s disease. nameOfConference DOI: 10.3233/JPD-191900 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/64717 Dobson R, Jitlal M, Marshall CR et al. (2020). Ethnic and Socioeconomic Associations with Multiple Sclerosis Risk. nameOfConference DOI: 10.1002/ana.25688 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62858 Blauwendraat C, Reed X, Krohn L et al. (2020). Erratum: Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia (Brain (2020) 143 (234-48) DOI: 10.1093/brain/awz350). nameOfConference DOI: 10.1093/brain/awaa036 QMRO: qmroHref Auger S, Noyce A (publicationYear). Testing shortened versions of smell tests to screen for hyposmia in Parkinson’s disease. nameOfConference DOI: 10.1002/mdc3.12928 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/63158 Dobson R, Noyce A, Giovannoni G et al. (2020). BMI and low serum vitamin D are causal risk factors for Multiple Sclerosis: a Mendelian Randomisation study. nameOfConference DOI: 10.1212/NXI.0000000000000662 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62737 Alarcón F, Maldonado JC, Cañizares M et al. (2020). Motor Dysfunction as a Prodrome of Parkinson's Disease. nameOfConference DOI: 10.3233/JPD-191851 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/66256 Noyce A, Ben-Joseph A, MARSHALL C et al. (publicationYear). Ethnic variation in the manifestation of Parkinson’s disease: a narrative review. nameOfConference DOI: 10.3233/JPD-191763 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62340 Nalls MA, Blauwendraat C, Vallerga CL et al. (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. nameOfConference DOI: 10.1016/S1474-4422(19)30320-5 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62389 Billingsley KJ, Barbosa IA, Bandrés-Ciga S et al. (2019). Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset. nameOfConference DOI: 10.1038/s41531-019-0080-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/69502 Reynolds RH, Botía J, Nalls MA et al. (2019). Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability. nameOfConference DOI: 10.1038/s41531-019-0076-6 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/69262 Bandres-Ciga S, Ahmed S, Sabir MS et al. (2019). The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population-Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight. nameOfConference DOI: 10.1002/mds.27864 QMRO: qmroHref Noyce AJ, Bandres-Ciga S, Kim J et al. (2019). The Parkinson's Disease Mendelian Randomization Research Portal. nameOfConference DOI: 10.1002/mds.27873 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/60502 Noyce A, International Parkinson’s Disease Genomics Consortium (IPDGC) (2020). Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia. nameOfConference DOI: 10.1093/brain/awz350 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62988 Bandres-Ciga S, Noyce A, Traynor BJ (publicationYear). Mendelian randomization: a journey from obscurity to center stage with a few potholes along the way. nameOfConference DOI: 10.1001/jamaneurol.2019.3419 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/62387 Noyce A, Iwaki H (2019). Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts. nameOfConference DOI: 10.1002/mds.27845 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/60007 Fernández-Santiago R, Martín-Flores N, Antonelli F et al. (2019). SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease. nameOfConference DOI: 10.1002/mds.27770 QMRO: qmroHref Neligan A, Noyce AJ, Gosavi TD et al. (2019). Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time. nameOfConference DOI: 10.1001/jamaneurol.2019.1268 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/59581 Iwaki H, Blauwendraat C, Leonard HL et al. (2019). Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts. nameOfConference DOI: 10.1212/NXG.0000000000000348 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/59505 Joseph T, Auger SD, Peress L et al. (2019). Screening performance of abbreviated versions of the UPSIT smell test. nameOfConference DOI: 10.1007/s00415-019-09340-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/57823 Hasan H, Burrows M, Athauda DS et al. (2019). The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect. nameOfConference DOI: 10.1002/mdc3.12798 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/58738 NOYCE AJ, Neligan A, Gosavi T et al. (2019). Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time A Systematic Review and Meta-analysis. nameOfConference DOI: 10.1001/jamaneurol.2019.1268 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/58383 NOYCE AJ, International Parkinson's Disease Genomics Consortium (IPDGC) (2019). Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms.. nameOfConference DOI: 10.1002/mds.27659 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/57077 Bandres-Ciga S, Saez-Atienzar S, Bonet-Ponce L et al. (2019). The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease. nameOfConference DOI: 10.1002/mds.27614 QMRO: qmroHref Heilbron K, NOYCE AJ, Fontanillas P et al. (2019). The Parkinson’s Phenome—Traits Associated with Parkinson's Disease in a Broadly Phenotyped Cohort. nameOfConference DOI: 10.1038/s41531-019-0077-5 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/57234 Schrag A, Anastasiou Z, Ambler G et al. (publicationYear). Predicting Diagnosis of Parkinson’s disease: A Risk Algorithm based on Primary Care presentations. nameOfConference DOI: 10.1002/mds.27616 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/55648 NOYCE AJ (2019). Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis. nameOfConference DOI: 10.1002/ana.25431 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/55486 Kia DA, Sabir MS, Ahmed S et al. (2018). LRP10 in α-synucleinopathies. nameOfConference DOI: 10.1016/S1474-4422(18)30401-0 QMRO: qmroHref NOYCE AJ, Rees R, Schrag A (2018). The prodromes of Parkinson's disease.. nameOfConference DOI: 10.1111/ejn.14269 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/55013 Acharya A, Basnett I, Gutteridge C et al. (2018). Laughter isn't always the best medicine.. nameOfConference DOI: 10.1136/bmj.k4579 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/56011 Blauwendraat C, Reed X, Kia DA et al. (2018). Frequency of loss of function variants in LRRK2 in Parkinson disease. nameOfConference DOI: 10.1001/jamaneurol.2018.1885 QMRO: qmroHref Rees RN, Acharya AP, Schrag A et al. (2018). An early diagnosis is not the same as a timely diagnosis of Parkinson's disease. nameOfConference DOI: 10.12688/f1000research.14528.1 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/55014 NOYCE AJ (2018). Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson’s disease.. nameOfConference DOI: 10.1002/ana.25294 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/42225 De Pablo-Fernandez E, Goldacre R, Pakpoor J et al. (2018). Association between diabetes and subsequent Parkinson disease: A record-linkage cohort study. nameOfConference DOI: 10.1212/WNL.0000000000005771 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/36482 Noyce A (2018). Remembering the man behind An Essay on the Shaking Palsy. nameOfConference DOI: 10.1016/S1474-4422(17)30467-2 QMRO: qmroHref Keddie S, Adams A, Kelso ARC et al. (2018). No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation. nameOfConference DOI: 10.1007/s00415-018-8801-3 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/35883 Weil RS, Schwarzkopf DS, Bahrami B et al. (2018). Assessing cognitive dysfunction in Parkinson's disease: An online tool to detect visuo-perceptual deficits. nameOfConference DOI: 10.1002/mds.27311 QMRO: qmroHref Shribman S, Noyce A, Gnanapavan S et al. (2018). Cryptococcal meningitis in apparently immunocompetent patients: Association with idiopathic CD4+ lymphopenia. nameOfConference DOI: 10.1136/practneurol-2017-001800 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32063 Blauwendraat C, Kia DA, Pihlstrøm L et al. (2018). Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease. nameOfConference DOI: 10.1016/j.neurobiolaging.2017.12.012 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/56452 Noyce AJ, Dickson J, Rees RN et al. (2018). Dopamine reuptake transporter–single-photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease. nameOfConference DOI: 10.1002/mds.27282 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32124 NOYCE AJ (2018). Assessing cognitive dysfunction in Parkinson’s: An online tool to detect visuo-perceptual deficits. nameOfConference DOI: 10.1002/mds.27311 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/36724 Shribman S, Hasan H, Hadavi S et al. (2018). The BRAIN test: a keyboard-tapping test to assess disability and clinical features of multiple sclerosis. nameOfConference DOI: 10.1007/s00415-017-8690-x QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32346 Noyce AJ, Lees A (2017). Observations on a 2-Step Approach to Screening for Parkinson Disease. nameOfConference DOI: 10.1001/jamaneurol.2017.3202 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/36338 Noyce A, Bandopadhyay R (2017). Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview.. nameOfConference DOI: 10.1007/978-3-319-57193-5_3 QMRO: qmroHref Raciborska DD, Noyce AJ, Pyne D et al. (publicationYear). Lupus myelopathy. nameOfConference DOI: 10.1136/practneurol-2017-001756 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31205 Lynch DS, Loh SHY, Harley J et al. (2017). Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations. nameOfConference DOI: 10.1212/NXG.0000000000000188 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32250 Noyce AJ, Kia DA, Hemani G et al. (2017). Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. nameOfConference DOI: 10.1371/journal.pmed.1002314 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/29543 Noyce A, Dickson J, Bestwick J et al. (2017). Associations of DAT SPECT and TCS with prodromal features of Parkinson's disease: Results in PREDICT-PD participants. nameOfConference DOI: doi QMRO: qmroHref Nagy A, Hardaker E, Bestwick J et al. (2017). Cognition in the PREDICT-PD Cohort. nameOfConference DOI: doi QMRO: qmroHref Noyce A, Kia D, Hemani G et al. (2017). Increased BMI May Protect against Parkinson's Disease: Evidence From Mendelian Randomisation Study. nameOfConference DOI: doi QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/29523 Pakpoor J, Noyce A, Goldacre R et al. (2017). Viral hepatitis and Parkinson disease: A national record-linkage study. nameOfConference DOI: 10.1212/WNL.0000000000003848 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32354 Magdalinou NK, Noyce AJ, Pinto R et al. (2017). Identification of candidate cerebrospinal fluid biomarkers in parkinsonism using quantitative proteomics. nameOfConference DOI: 10.1016/j.parkreldis.2017.01.016 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/29063 Noyce AJ, Schrag A, Masters JM et al. (2017). Subtle motor disturbances in PREDICT-PD participants.. nameOfConference DOI: 10.1136/jnnp-2016-314524 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/29663 Hasan H, Athauda DS, Foltynie T et al. (2017). Technologies Assessing Limb Bradykinesia in Parkinson’s Disease. nameOfConference DOI: 10.3233/JPD-160878 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32337 Noyce AJ, R'Bibo L, Peress L et al. (2017). PREDICT-PD: An online approach to prospectively identify risk indicators of Parkinson's disease.. nameOfConference DOI: 10.1002/mds.26898 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/29563 Lubbe SJ, Escott-Price V, Gibbs JR et al. (publicationYear). Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance. nameOfConference DOI: 10.1093/hmg/ddw348 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31143 Adams-Carr KL, Bestwick JP, Shribman S et al. (2016). Constipation preceding Parkinson's disease: a systematic review and meta-analysis.. nameOfConference DOI: 10.1136/jnnp-2015-311680 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/49431 Hasan H, Athauda DS, Foltynie T et al. (2016). Objective decrement in Parkinson's disease - A new parameter for the BRAIN tap test. 20th International Congress of Parkinson's Disease and Movement Disorders DOI: doi QMRO: qmroHref Masters JM, Noyce AJ, Lynham S et al. (2016). A comprehensive characterisation of the salivary proteome of patients with Parkinson's disease. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Schrag A, Masters J et al. (2016). Blinded video assessment of subtle Parkinsonian signs in PREDICT-PD participants. nameOfConference DOI: doi QMRO: qmroHref Mok KY, Sheerin U, Simon-Sanchez J et al. (2016). Deletions at 22q11.2 in idiopathic Parkinson's disease: A combined analysis of GWAS data. nameOfConference DOI: doi QMRO: qmroHref R'Bibo L, Mencacci NE, Schrag A et al. (2016). Exploring association of GBA variants with pre-diagnostic features of PD in the PREDICT-PD cohort: A nested case-control study. nameOfConference DOI: doi QMRO: qmroHref Simonet C, Noyce AJ, Ling H et al. (2016). Handwriting in Parkinson's disease: Systematic review and preliminary study. nameOfConference DOI: doi QMRO: qmroHref Osborne CW, Bestwick J, Giovannoni G et al. (2016). Participant feedback in the PREDICT-PD study. nameOfConference DOI: doi QMRO: qmroHref Salat D, Noyce AJ, Schrag A et al. (2016). Challenges of modifying disease progression in prediagnostic Parkinson's disease. nameOfConference DOI: 10.1016/S1474-4422(16)00060-0 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32049 Mok KY, Sheerin U, Simón-Sánchez J et al. (2016). Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data. nameOfConference DOI: 10.1016/S1474-4422(16)00071-5 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31024 Noyce AJ, Nalls MA (2016). Mendelian Randomization - the Key to Understanding Aspects of Parkinson's Disease Causation?. nameOfConference DOI: 10.1002/mds.26492 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31083 Noyce AJ, Lees AJ, Schrag A-E (2016). The prediagnostic phase of Parkinson's disease. nameOfConference DOI: 10.1136/jnnp-2015-311890 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/32347 Noyce A, Bestwick J, Mencacci N et al. (2015). PREDICT-PD: Identifying Risk of Parkinson's disease in the Community. nameOfConference DOI: doi QMRO: qmroHref Masters JM, Bestwick J, Warner TT et al. (2015). Systematic review and meta-analysis of salivary protein concentration in Parkinson's disease. nameOfConference DOI: 10.1002/mds.26462 QMRO: qmroHref Adams-Carr K, Schrag A, Shribman S et al. (2015). CONSTIPATION PRECEDING PARKINSON'S DISEASE–META-ANALYSIS. nameOfConference DOI: 10.1136/jnnp-2015-312379.98 QMRO: qmroHref Masters J, Noyce A, Giovannoni G et al. (2015). ELEVATED SALIVARY DJ-1 IN PARKINSON'S DISEASE IS ASSOCIATED WITH ALTERED SALIVARY SECRETION. nameOfConference DOI: 10.1136/jnnp-2015-312379.23 QMRO: qmroHref Nalls MA, McLean CY, Rick J et al. (2015). Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: A population-based modelling study. nameOfConference DOI: 10.1016/S1474-4422(15)00178-7 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31923 Masters JM, Noyce AJ, Warner TT et al. (2015). Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity. nameOfConference DOI: 10.1016/j.parkreldis.2015.07.021 QMRO: qmroHref Adams-Carr KL, Schrag A, Shribman S et al. (2015). Constipation preceding Parkinson's disease - Systematic review and meta-analysis. nameOfConference DOI: doi QMRO: qmroHref Masters JM, Noyce AJ, Giovannoni G et al. (2015). Elevated salivary DJ-1 in Parkinson's disease is associated with altered salivary secretion. nameOfConference DOI: doi QMRO: qmroHref Athauda DS, Hasan H, Noyce A et al. (2015). Evaluating the use of the online bradykinesia-akinesia Incoordination (BRAIN) test in Parkinson's disease in "on" and "off" states. nameOfConference DOI: doi QMRO: qmroHref Nagy A, Noyce A, Velayos-Baeza A et al. (2015). Late Emergence of Parkinsonian Phenotype and Abnormal Dopamine Transporter Scan in Chorea-Acanthocytosis. nameOfConference DOI: 10.1002/mdc3.12138 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/31025 Magdalinou N, Ling H, Noyce A et al. (2015). The visual estimation of midbrain to pons ratio combined with cerebrospinal fluid biomarkers improves the diagnostic accuracy of PSP. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Mencacci NE, Schrag A et al. (2015). Web-based assessment of Parkinson's prodromal markers identifies GBA variants. nameOfConference DOI: 10.1002/mds.26249 QMRO: qmroHref Schrag A, Horsfall L, Walters K et al. (2015). Prediagnostic presentations of Parkinson's disease in primary care: A case-control study. nameOfConference DOI: 10.1016/S1474-4422(14)70287-X QMRO: qmroHref Shribman SE, Noyce AJ, Martin JE et al. (2014). The distribution of alpha-synuclein in the enteric nervous system: An immunohistochemical study on colonic resections from 24 control and 4 Parkinson's disease patients. nameOfConference DOI: doi QMRO: qmroHref Torsney KM, Noyce AJ, Doherty KM et al. (2014). Bone health in Parkinson's disease: a systematic review and meta-analysis.. nameOfConference DOI: 10.1136/jnnp-2013-307307 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/37224 Osborne C, Noyce A, Sylvester R (2014). AUTO-REGULATION ICP IN IIH DUE TO CHRONIC CSF LEAK. nameOfConference DOI: 10.1136/jnnp-2014-309236.105 QMRO: qmroHref Mencacci NE, Isaias IU, Reich MM et al. (2014). Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.. nameOfConference DOI: 10.1093/brain/awu179 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/37203 Noyce AJ, Nagy A, Acharya S et al. (2014). Correction: Bradykinesia-akinesia incoordination test: Validating an online keyboard test of upper limb function (PLoS ONE (2014) 9, 4 (e96260) DOI: 10.1371/journal.pone.0096260). nameOfConference DOI: 10.1371/journal.pone.0105488 QMRO: qmroHref Osborne C, Stallworthy S, Evanson J et al. (2014). Rapid-onset flaccid paraplegia caused by multiple myeloma dumbbell tumour.. nameOfConference DOI: 10.1136/practneurol-2013-000767 QMRO: qmroHref Shribman S, Torsney KM, Noyce AJ et al. (2014). A service development study of the assessment and management of fracture risk in Parkinson's disease.. nameOfConference DOI: 10.1007/s00415-014-7333-8 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/42544 Shribman SE, Torsney K, Noyce AJ et al. (2014). A service development study of the assessment and management of fracture risk in Parkinson's disease. nameOfConference DOI: doi QMRO: qmroHref Torsney KM, Noyce AJ, Doherty KM et al. (2014). A systematic review and meta-analysis of fracture risk in Parkinson's disease. nameOfConference DOI: doi QMRO: qmroHref Torsney KM, Noyce AJ, Doherty KM et al. (2014). Bone health in Parkinson's disease: A systematic review and meta-analysis. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Mencacci N, Schrag A et al. (2014). GBA1 and LRRK2 mutations in higher and lower risk subjects from the PREDICT-PD project. nameOfConference DOI: doi QMRO: qmroHref Mencacci NE, Isaias IU, Reich MM et al. (2014). Parkinson's disease in GTP cyclohydrolase-1 mutation carriers. nameOfConference DOI: doi QMRO: qmroHref Shribman SE, Noyce AJ, Martin JE et al. (2014). The distribution of alpha-synuclein in the enteric nervous system: An immunohistochemical study on colonic resections from 24 control and 4 Parkinson's disease patients. nameOfConference DOI: doi QMRO: qmroHref Nagy A, Noyce A, Lees A et al. (2014). Two cases of abnormal dopamine transporter scan in chorea-acanthocytosis. nameOfConference DOI: doi QMRO: qmroHref Nalls MA, Saad M, Noyce AJ et al. (2014). Genetic comorbidities in Parkinson's disease. nameOfConference DOI: 10.1093/hmg/ddt465 QMRO: qmroHref Noyce AJ, Nagy A, Acharya S et al. (2014). Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function.. nameOfConference DOI: 10.1371/journal.pone.0096260 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/37223 Noyce AJ, Bestwick JP, Silveira-Moriyama L et al. (2014). PREDICT-PD: Identifying risk of Parkinson's disease in the community: Methods and baseline results. nameOfConference DOI: 10.1136/jnnp-2013-305420 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/41483 Hadavi S, Shribman S, Nagy A et al. (2013). The bradykinesia-akinesia incoordination test: a simple objective test in multiple sclerosis.. nameOfConference DOI: 10.1136/jnnp-2013-306573.184 QMRO: qmroHref Nagy A, Acharya S, Hadavi S et al. (2013). Bradykinesia-akinesia incoordination test: Validating an online keyboard test of upper limb function. nameOfConference DOI: doi QMRO: qmroHref Djamshidian A, O'Sullivan SS, Foltynie T et al. (2013). Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Bestwick JP, Silveira-Moriyama L et al. (2013). PREDICT-PD study: Online screening algorithm identifying Parkinson's disease risk. nameOfConference DOI: doi QMRO: qmroHref Dobson R, Yarnall A, Noyce AJ et al. (2013). Bone health in chronic neurological diseases: a focus on Multiple sclerosis and Parkinsonian syndromes.. nameOfConference DOI: 10.1136/practneurol-2012-000435 QMRO: qmroHref Djamshidian A, O'Sullivan SS, Foltynie T et al. (2013). Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease.. nameOfConference DOI: 10.3233/JPD-130178 QMRO: qmroHref Noyce AJ, Bestwick JP, Silveira-Moriyama L et al. (2012). Meta-analysis of early nonmotor features and risk factors for Parkinson disease.. nameOfConference DOI: 10.1002/ana.23687 QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/48303 Chan MV, Bubb KJ, Noyce A et al. (2012). Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.. nameOfConference DOI: 10.1111/j.1476-5381.2012.02012.x QMRO: qmroHref Noyce AJ, Bestwick J, Silveira-Moriyama L et al. (2012). Risk factors and early non-motor features for Parkinson's disease: A systematic review and meta-analysis. nameOfConference DOI: doi QMRO: qmroHref Acharya S, Nagy A, Budu C et al. (2012). The new bradykinesia akinesia incoordination (BRAIN) test: People with Parkinson's disease versus healthy controls. nameOfConference DOI: doi QMRO: qmroHref Noyce A, Silveira-Moriyama L, Lees AJ et al. (2012). A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE. nameOfConference DOI: 10.1136/jnnp-2011-301993.161 QMRO: qmroHref Noyce A, Bestwick J, Hawkes CH et al. (2012). AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY. nameOfConference DOI: 10.1136/jnnp-2011-301993.162 QMRO: qmroHref Noyce AJ, Silveira-Moriyama L, Gilpin P et al. (2012). Severe dysphagia as a presentation of Parkinson's disease.. nameOfConference DOI: 10.1002/mds.24006 QMRO: qmroHref Noyce A, Treacy C, Budu C et al. (2012). THE NEW BRADYKINESIA AKINESIA INCOORDINATION (BRAIN) TEST: AN ONLINE TEST OF UPPER LIMB MOVEMENT. nameOfConference DOI: 10.1136/jnnp-2011-301993.160 QMRO: qmroHref Doherty KM, Silveira-Moriyama L, Nisbet A et al. (2012). 0854 Camptocormia: what is the cause?. nameOfConference DOI: 10.1136/jnnp-2011-301993.40 QMRO: qmroHref Doherty KM, Noyce AJ, Silveira-Moriyama L et al. (2012). Familial camptocormia: From dystonia to myopathy. nameOfConference DOI: 10.1136/jnnp.2011.246561 QMRO: qmroHref Noyce AJ, Treacy C, Budu C et al. (2012). The new Bradykinesia Akinesia Incoordination (BRAIN) test: Preliminary data from an online test of upper limb movement. nameOfConference DOI: 10.1002/mds.23947 QMRO: qmroHref Hadavi S, Noyce AJ, Leslie RD et al. (2011). Stiff person syndrome.. nameOfConference DOI: 10.1136/practneurol-2011-000071 QMRO: qmroHref Hadavi SY, Bahra M, Noyce AJ et al. (2011). POTENTIAL FOR SERIOUS UNDER-REPORTING OF PRESCRIBING ERRORS BY NEWLY-QUALIFIED DOCTORS. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Bestwick J, Hawkes CH et al. (2011). A pilot study of an algorithm designed to identify Parkinson's disease in the early, non-motor phase. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Bestwick J, Hawkes CH et al. (2011). An algorithm to identify individuals at high-risk of Parkinson's disease in the community. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, Gilpin P, Howard R et al. (2011). Severe dysphagia preceding Parkinson's disease. nameOfConference DOI: doi QMRO: qmroHref Noyce AJ, McCrae S, Gawler J et al. (2010). Teaching NeuroImages: microhemorrhages resulting from cranial radiotherapy in childhood.. nameOfConference DOI: 10.1212/WNL.0b013e3181e620df QMRO: qmroHref Shah M, Deeb J, Fernando M et al. (2009). Abnormality of taste and smell in Parkinson's disease.. nameOfConference DOI: 10.1016/j.parkreldis.2008.05.008 QMRO: qmroHref Shah M, Deeb J, Fernando M et al. (2007). Taste is abnormal in Parkinson disease and suggests cortical spread. nameOfConference DOI: doi QMRO: qmroHref Noyce AL, Hetley RS, Dobias JJ et al. (2007). Perception of local rigidity due to lines in rotating random-dot textures viewed through an aperture. nameOfConference DOI: doi QMRO: qmroHref Shah M, Deeb J, Fernando M et al. (2007). Taste threshold is abnormal in Parkinson's disease and suggests cortical spread. nameOfConference DOI: doi QMRO: qmroHref Shah M, Noyce A, Deeb J et al. (2006). Chemosensory measurement in essential tremor. nameOfConference DOI: doi QMRO: qmroHref Shah M, Noyce A, Deeb J et al. (2006). Smell identification and taste threshold are normal in essential tremor. nameOfConference DOI: doi QMRO: qmroHref Shah M, Noyce A, Deeb J et al. (2006). Chemosensory measurement in essential tremor. nameOfConference DOI: doi QMRO: qmroHref Noyce A, Shah M, Deeb J et al. (2006). Chemosensory measurement in essential tremor. nameOfConference DOI: doi QMRO: qmroHref SupervisionCristina Simonet, Martin Escudero Foundation, Motor Prodromes of Parkinson's Disease Brook Huxford, Wolfson PhD studentship, Remote Biomarkers for Parkinson's Disease Jonggeol Kim, Global Parkinson's Genetics Programme, Genetic Determinants of Parkinson's Disease Benjamin Jacobs (subsidiary supervisor), MRC, Genetic Association study in individuals of Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS)