Professor Alastair Noyce, BMedSci, MB BS, MSc, MRCP, PhD, FHEA

Profile

I am a Professor in Neurology and Neuroepidemiology in the Centre for Preventive Neurology (CPN), in the Wolfson Institute of Population Health, Queen Mary University of London (QMUL). I am the deputy lead for the CPN and a Consultant Neurologist at Barts Health NHS Trust.

I graduated from Barts and the London (QMUL) in 2007 and I pursued integrated training via the Foundation Academic Programme and an NIHR Academic Clinical Fellowship at UCL. Between 2012-2016 I undertook a PhD in Neuroscience at UCL and between 2014-2016 I undertook an MSc in Epidemiology at London School of Hygiene and Tropical Medicine. I re-joined QMUL and the PNU in 2017 to lead the Parkinson’s programme of work.

My research interests are Parkinson’s disease and other neurodegenerative disorders, particularly early identification and epidemiological aspects, including environmental, clinical and genetic determinants. I am the co-principal investigator of the PREDICT-PD study, principal investigator for the East London Parkinson’s Disease project and chief investigator for the Access-PD study.

I am a member of the International Parkinson and Movement Disorder Society (MDS). I graduated from the MDS LEAP leadership programme in 2020, and then became a member of the faculty for the LEAP, teaching leadership skills to early career movement disorders specialists around the world. I am the Chair of the MDS Epidemiology Study Group, a member of the MDS Early Onset PD Study Group and the Equality of Access to Care Committee. I on the Global Parkinson’s Genetics Program (GP2) and lead two of its working groups, focusing on Training and Networking and Prodromal PD. I am Associate Editor for the Journal of Parkinson’s Disease.

Away from neurodegenerative disease, I am interested in the emerging link between recreational use of nitrous oxide (laughing gas) and neurological harm. I have led the drafting of national guidance for managing the range of neurological conditions associated with nitrous oxide, as well as describing the clinical manifestations in patients in order to raise awareness amongst healthcare workers.

Research

Research Interests:

Neurology

Epidemiology

Genetics

Predictive models

Clinical research

Publications

• Mitchell E, Mattjie C, Bestwick JP et al. (publicationYear). Hyposmia in Parkinson’s disease; exploring selective odour loss. nameOfConference

  
  

  DOI: 10.1038/s41531-025-00922-3

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/105913
• Mehanna R, Marras C, Fleisher J et al. (2025). Diagnostic Work Up when Suspecting Early Onset Parkinson Disease (EOPD). Recommendations from the MDS EOPD Study Group.. nameOfConference

  
  

  DOI: 10.1016/j.parkreldis.2025.107852

  
  

  QMRO: qmroHref
• Lim S-Y, all the authors, Tan AH et al. (2025). The Genetic Epidemiology of Parkinson's Disease view – Authors' reply. nameOfConference

  
  

  DOI: 10.1016/s1474-4422(25)00073-0

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/105912
• Schlickmann TH, Tessari MS, Borelli WV et al. (2025). Prevalence, distribution and future projections of Parkinson disease in Brazil: insights from the ELSI-Brazil cohort study. nameOfConference

  
  

  DOI: 10.1016/j.lana.2025.101046

  
  

  QMRO: qmroHref
• Chahine LM, Lafontant D-E, Choi SH et al. (2025). LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization. nameOfConference

  
  

  DOI: 10.1093/braincomms/fcaf103

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/105911
• Zabihi S, Bestwick JP, Jitlal M et al. (2025). Early presentations of dementia in a diverse population. nameOfConference

  
  

  DOI: 10.1002/alz.14578

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/105085
• Azoidou V, Rowsell K, Camboe E et al. (2025). A pilot interventional study on feasibility and effectiveness of the CUE1 device in Parkinson's disease. nameOfConference

  
  

  DOI: 10.1016/j.parkreldis.2025.107349

  
  

  QMRO: qmroHref
• Zaloum SA, Mair D, Paris A et al. (2025). Tackling the growing burden of nitrous oxide-induced public health harms. nameOfConference

  
  

  DOI: 10.1016/s2468-2667(24)00298-6

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/104729
• Paris A, Amirthalingam G, Karania T et al. (2025). Depression and dementia: interrogating the causality of the relationship. nameOfConference

  
  

  DOI: 10.1136/jnnp-2024-334675

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/103851
• Wang X, Bindoff A, St George RJ et al. (2024). Tapping into a new hand‐motor biomarker of the dementia continuum ‐ integration and validation in a cognitive clinic. nameOfConference

  
  

  DOI: 10.1002/alz.088451

  
  

  QMRO: https://qmro.qmul.ac.uk/xmlui/handle/123456789/103820

Supervision

Jonggeol Kim, Global Parkinson's Genetics Programme, Genetic Determinants of Parkinson's Disease

Benjamin Jacobs (subsidiary supervisor), MRC, Genetic Association study in individuals of Diverse Ancestral backgrounds with Multiple Sclerosis (ADAMS)

Alex Zirra, The Medical College of St Bartholomew’s Hospital Trust, Cognitive features of Parkinson’s disease in a diverse population

Ellen Camboe, Barts Charity, Parkinson’s Disease Psychosis in a Diverse Population

Harneek Chohan, Early clinical and biological markers in Parkinson's Disease