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Professor Zudin Puthucheary

Zudin

Professor of Intensive Care Medicine

Centre: Critical Care and Perioperative Medicine Group

Email: z.puthucheary@qmul.ac.uk
Telephone: +44(0) 20 3594 0319
X: @Zudin_P

Profile

ORCID iD: 0000-0003-4267-1892

Zudin graduated from Nottingham University in 1997, and moved to London post MRCP in 2000. Following a 3-year stint in Sydney, he started his Respiratory training in Bristol, before completing his critical care training in London. His research focusses on acquired functional disability, and the use of metabolic, nutritional and exercise interventions to prevent and treat muscle. Zudin is a nationally elected Council member of the Intensive Care Society (UK) and a trustee for the National Confidential Enquiry into Patient Outcome and Death.

His work on acute muscle wasting has won awards from the European Society of Intensive Care Medicine , European Society of Anaesthesia, the British Thoracic Society, the Intensive Care Society, The American Society of Enteral and Parenteral Nutrition and Zudin was named a Global Rising Star by the Australia and New Zealand Intensive Care Society. He setup and chaired the UK National Post-Intensive Care Rehabilitation Collaborative until 2023, a multi-professional cross-disciplinary group focussing on rehabilitation and restitution of critical illness survivors.

Research

Critical Care and Perioperative Medicine Group

Our research is focused on both primary and secondary prevention of acquired functional disability following critical illness. We are primarily focused on physical disability- loss of muscle mass and the resultant decrease in physical activity, and attempts to modify this using metabolic, nutritional and exercise interventions. In addition, we seek to understand the patient population in terms of pre-existing multi-morbidity and frailty as important predisposing factors to disability, and as limiters to functional recovery. We continue to develop and refine tools for both identifying (biological signatures) and assessing (e.g the PICUPS tool) new functional disability.

Publications

  • Fazzini B, Kelly E, Mathieson G et al. (2027). Acceptability of advanced monitoring for acute respiratory failure requiring non-invasive respiratory support: A qualitative study of perceptions from patients and critical care practitioners. nameOfConference


    QMRO: qmroHref
  • King E, Wyer N, Barghouthy D et al. (2026). Patient and clinician acceptability of an integrated physiotherapy and nutrition intervention after ICU discharge: a qualitative exploration of a pre-specified co-primary feasibility outcome of the PHOENIX trial. nameOfConference


  • Ntoumenopoulos G, Hansell L, Parry SM et al. (2026). Diaphragm and Skeletal Muscle Changes During Intensive Care: Association With Patient Outcomes (DRASTIC): Observational Study. nameOfConference


  • McWilliams D, Gustafson O, Wyer N et al. (2026). Physiotherapy and optimised enteral nutrition in the post-acute phase of critical illness (PHOENIX): a randomised controlled feasibility trial. nameOfConference


  • Azzopardi G, Davies T, Lewis MJ et al. (2026). Creatinine muscle index in UK Biobank: comparison with MRI and associations with frailty and mortality. nameOfConference


  • Kelly E, Hako J, Chapman AC et al. (2026). Measurement Techniques and Properties of Single-item Measures for the Evaluation of Oropharyngeal Muscle Function in Adults with Dysphagia: A Systematic Review using the COSMIN Framework. nameOfConference


  • Puthucheary ZA, Van De Poll MCG (2026). Is there really no harm in trying? The Cahill cycle and high-dose protein in critical illness. nameOfConference


  • Nazeer S, Mathieson G, Puthucheary Z et al. (publicationYear). A qualitative study exploring critical care survivors’ and their clinicians’ shared experiences of navigating a fragmented care system. nameOfConference


  • Bath MF, Amoako J, Edmiston T et al. (2026). Defining the bellwether procedures and processes for global trauma care: an international Delphi study. nameOfConference


  • Alcaide M, Puthucheary Z, Prowle JR (2026). Macronutrient excess in critical illness: too much of a good thing?. nameOfConference


View profile publication page

Collaborators

Internal

  • Dr John Prowle
  • Prof Gareth Ackland
  • Prof Andrew Prendegast
  • Prof Aylin Basan
  • Prof Sian Henson
  • Prof Adina Michael-Titus

External

International:

  • Profs Linda Denehey and Sue Berney (University of Melbourne)
  • Prof Stephen Olde Damick (University of Maastricht)
  • Sepsis and Critical Illness Research Centre (University of Florida)
  • Dr Louise Thwaites (Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh, Vietnam) 

National:

  • Medical Research Council/Arthritis Research UK Centre of excellence for musculoskeletal ageing research (University of Nottingham)
  • Centre of Human and Aerospace Physiological Sciences (Kings College London)
  • Centre for Human Health and Performance (University College London)

Disclosures

  • GlaxoSmithKline - Specialist Advisory Board for muscle wasting in critical illness
  • Fresunius Kabi - Specialist Advisory Board for functional recovery post-critical illness
  • Lyric Pharmaceuticals - Consultant
  • Faraday Pharmaceuticals - Consultant
  • Nestle - Specialist Advisory Board for muscle wasting in critical illness
  • Nutricia - Specialist Advisory Board for mitochondrial dysfunction in critical illness
  • Bioage - Consultant
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