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The William Harvey Research Institute - Faculty of Medicine and Dentistry

Latest news

New £11.6 million PhD Programme for health research in underrepresented populations
30 November 2021

The Health Advances in Underrepresented Populations and Diseases (HARP) PhD Programme focuses research towards people and diseases that have traditionally been underrepresented in healthcare studies.

Researcher holding a pipette in a laboratory. Outstanding technician awarded Papin Prize at HETS2021
15 November 2021

A technician from the William Harvey Research Institute at Queen Mary University of London has been presented with a prestigious award which recognises excellence in academia at the UK’s only event dedicated to celebrating the success and achievements of technical staff. 

Whole genome sequencing improves diagnosis of rare diseases and shortens diagnostic journeys for patients
11 November 2021

A world-first scientific study, published today in the New England Journal of Medicine, has shown that whole genome sequencing (WGS) can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS.

New app helps parents identify treatable childhood growth disorders earlier
9 November 2021

A new mobile phone app, ‘GrowthMonitor’, places the accurate measurement of children’s height in the hands of parents and carers. 

PhD student to co-host COP26 event
2 November 2021

Nikita Patel has been selected to co-host an event at the United Nations Climate Change Conference (COP26) in Glasgow on November 4th.

Researcher holding a pipette in a laboratory. WHRI research technician recognised for contribution to endocrine research
13 October 2021

A research technician from the William Harvey Research Institute at Queen Mary University of London has been shortlisted for a Papin Prize, the UK’s only award dedicated to celebrating technical excellence and innovation in higher education and research.

Queen Mary researchers help develop nasal spray that prevents Covid-19
27 September 2021

Queen Mary University of London professors Rakesh Uppal and Áine McKnight have been at the centre of a new clinical trial finding that pHOXWELL – a nasal spray developed by biotech company pHOXBIO - reduced SARS-CoV-2 infection by 63 per cent in the group given pHOXWELL compared to the group given the placebo. SARS-CoV-2 is the virus that causes Covid-19.

New model could improve treatment of rheumatoid arthritis patients with cardiac disease
16 September 2021

Researchers from Queen Mary University of London have developed a new approach to address cardiac disease in rheumatoid arthritis patients.

New study links COVID-19 genetic susceptibility with blood clots, thrombophlebitis and circulatory diseases
7 September 2021

Research led by Queen Mary University of London associates genetically predicted COVID-19 susceptibility with increased blood clot events in legs and lungs, thrombophlebitis, and circulatory diseases.

Hospital sign in London. Credit: georgeclerk/iStock.com. New study reveals patients from minority ethnic groups are more likely to be admitted to hospital
19 August 2021

Patients from minority ethnic groups have a disproportionately higher rate of emergency hospital admissions, according to research by Queen Mary University of London and Barts Health NHS Trust.

The image depicts a postcapillary venule subjected to acute inflammation and captures  neutrophils (green) transmigrating across endothelial cells junctions (blue).  Neutrophils preferably migrate across contacts between autophagy deficient endothelial cells (magenta). New insights into mechanisms of immune cell trafficking in inflammation
16 August 2021

A new study led by researchers at Queen Mary University of London has identified the intracellular catabolic recycling system, Autophagy, within endothelial cells as a new molecular mechanism to limit inflammation. 

Image of a pregnant woman. Photo by freestocks on Unsplash. Researchers successfully identify new gene variants that cause hypertension in pregnant women
12 August 2021

An international study, led by researchers from Queen Mary University of London and St Bartholomew’s Hospital, has found a unique pair of gene variants that causes sudden onset high blood pressure in pregnant women.

UK number one position for BSc Pharmacology and Innovative Therapeutics - National Student Survey 2021
26 July 2021

The BSc Pharmacology & Innovative Therapeutics degree programme led by Dr Sadani Cooray at the William Harvey Research Institute at Barts and the London School of Medicine and Dentistry has topped the national subject leader board and is currently number one in the UK having received the highest overall ratings in the 2021 National Student Survey (NSS).

New insights into uncontrolled inflammation in COVID-19 patients
21 July 2021

Research led by Queen Mary University of London provides new insight into the mechanisms that lead to uncontrolled inflammation in COVID-19 patients.

A photo showing intermediate age-related macular degeneration. Breakthrough into leading cause of blindness
19 July 2021

A team of scientists, including researchers from Queen Mary University of London, has discovered that the most common form of adult blindness is probably caused by a failure of at least one of five proteins to regulate the immune system.

MiniMed 640G Insulin Pump PTH infused insulin pump used as an alternative treatment for young patients with ADH1
8 July 2021

Researchers from Queen Mary University of London and the University of Oxford have developed an alternative treatment to increase calcium levels and prevent seizures in patients with the genetic condition ADH1.

Heart MRI scan showing the area of fat detected by the AI tool AI predicts diabetes risk by measuring fat around the heart
7 July 2021

A team led by researchers from Queen Mary University of London has developed a new artificial intelligence (AI) tool that is able to automatically measure the amount of fat around the heart from MRI scan images.

SynAct Pharma AB announces positive data from a Phase 2a trial of AP1189 in Covid-19 infected patients
1 July 2021

SynAct Pharma AB (“SynAct”) has just announced topline results from the Phase 2a clinical trial of AP1189 in Covid-19 infected patients with pulmonary insufficiency. Patients treated with 100mg AP1189 orally once-daily for 2-weeks achieved respiratory recovery (time to normalization of oxygen saturation on ambient air) on average 3.5 days (35%) quicker than placebo treated patients (6.4 days and 9.9 days on average respectively). Data from this exploratory pilot clinical trial supports that AP1189 may help Covid-19 infected patients recover impaired lung function.

Hospital First nationwide study reveals millions of cancelled operations due to COVID-19 and high risk of death
18 June 2021

The first nationwide study of the impact of COVID-19 on surgery at NHS hospitals has revealed that more than 1.5 million operations were cancelled or postponed during the pandemic and surgical patients who became infected with COVID were five times more likely to die.

Portrait photo of Dr Zahra Raisi-Estabargh Dr Zahra Raisi-Estabragh wins prestigious Royal Society of Medicine President's Gold Medal in Cardiology
18 June 2021

Congratulations to Dr Zahra Raisi-Estabragh who was recently awarded the Royal Society of Medicine (RSM) President’s Gold Medal in Cardiology in recognition of her work developing cardiovascular magnetic resonance (CMR) radiomics as a novel imaging biomarker.

Heart rate smart watch Could your smart watch alert you to risk of sudden death?
8 June 2021

Scientists develop a new algorithm that could allow wearable technology to warn those at risk of dangerous heart rhythm changes.

Renal denervation system Procedure using ultrasound energy found to treat high blood pressure
7 June 2021

A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

Ramadan fasting: recommendations for patients with cardiovascular disease
17 May 2021

A new publication led by cardiologists and researchers at the Barts Heart Centre and Queen Mary University of London has developed a framework for triaging and where possible, facilitating safe fasting in patients with cardiovascular disease.

Heart Having a healthier heart is associated with better problem-solving and reaction time
14 May 2021

People with healthier heart structure and function appear to have better cognitive abilities, including increased capacity to solve logic problems and faster reaction times, according to research led by Queen Mary University of London and the Radcliffe Department of Medicine at University of Oxford.

Professor Munroe elected to prestigious fellowship
13 May 2021

Congratulations to Professor Patricia Munroe who has been elected to the highly prestigious Academy of Medical Sciences Fellowship.

A brain scan Scientists uncover secret of the hunger switch in the brain
16 April 2021

A 3D structure reveals how a unique molecular switch in our brain causes us to feel full – and may help develop improved anti-obesity drugs.

How preprints accelerated science communication during the pandemic
8 April 2021

A new study led by Queen Mary University of London researchers has found that during the early phase of the pandemic, approximately 35 per cent of the COVID-19 scientific literature was shared as preprints – freely available manuscripts that are shared prior to peer-review in a journal.

Call for cardiovascular scientists to contribute data to multinational platform
6 April 2021

The first international platform for sharing cardiovascular data has been launched by euCanSHare, an EU-Canada funded project. Cardiovascular researchers are encouraged to use the platform to browse, deposit and analyse data.

£54-million-award-to-transform-health-through-data-science New genetic clues point to new treatments for ‘silent’ stroke
26 March 2021

Scientists from Queen Mary University of London have helped identify new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia.

WHRI research funding success
19 March 2021

In the past few months, the William Harvey Research Institute at Queen Mary University of London has seen major funding success in the areas of endocrine and inflammation research.

Why the Dutch are the tallest people in the world
16 March 2021

'Humans are growing taller around the world. The average adult today is 5% taller than they were a century ago. But how tall could humans get in the future, and what can we learn from the tallest people in the world – the Dutch?'

Illustration of a group social distancing School reopening without robust COVID-19 mitigation risks accelerating the pandemic
10 March 2021

A group of academics have set out a series of recommendations for schools to reduce the risk of COVID-19 transmission now that they have re-opened, in a letter published in The Lancet.

Heart Having an unhealthy heart could lead to a higher risk of being diagnosed with COVID-19
9 March 2021

People with unhealthy heart structures and poorer functioning hearts have a significantly higher risk of being diagnosed with COVID-19 infection, according to research by Queen Mary University of London, in collaboration with the Medical Research Council Lifecourse Epidemiology Unit (The University of Southampton).

WHRI academic wins prestigious Wellcome Trust Career Re-Entry fellowship for research into Type 2 diabetes
25 January 2021

Dr Dunja Aksentijevic, Senior Lecturer in Cardiovascular Physiology and Metabolism at Queen Mary University of London, awarded £630,000 for examining immunometabolic cross-talk in the inflamed type 2 diabetic heart.

Professor Costantino Pitzalis Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): outcomes of a stratified, biopsy-driven, multicentre, RCT
22 January 2021

A new study published today in The Lancet is the first stratified, biopsy-driven, multicentre, open-label, randomised controlled trial that takes the first steps in the integration of molecular pathology into treatment decision making in Rheumatoid Arthritis. 

In this Q&A Professor Costantino Pitzalis from the Centre for Experimental Medicine and Rheumatology at Queen Mary's William Harvey Research Institute explains why the R4RA trial represents the first step towards precision medicine.

Hospital Patients from Asian and black backgrounds are more likely to die from COVID-19, large study reveals
22 January 2021

Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust.

WHRI New Year PhD Symposium
21 January 2021

Wednesday 27th January from 1.00pm on Microsoft Teams

Illustration of a group social distancing Herd immunity by infection is not an option
15 January 2021

In an article, published today in Science, Dr Deepti Gurdasani from Queen Mary University of London and Devi Sridhar from the University of Edinburgh explain why herd immunity by infection is not a strategy that should be considered for COVID-19.

£54-million-award-to-transform-health-through-data-science Genes could be key to new Covid-19 treatments, study finds
14 December 2020

Potential treatments for Covid-19 have been identified after the discovery of five genes associated with the most severe form of the disease, in research involving Queen Mary academics.

UK, EU, Parliment No deal Brexit could have detrimental impact for four million people in UK living with a rare disease
12 December 2020

Experts have warned that a ‘no deal’ Brexit will result in the exclusion of the UK from the 24 European Reference Networks (ERNs) that were established to improve the care of patients bearing the lifelong burden of a rare disease, which require highly specialised diagnosis and treatment.

Professor Steffen Petersen Queen Mary researcher elected as President of prestigious cardiology association
11 December 2020

Steffen Petersen, Professor of Cardiovascular Medicine at Queen Mary University of London, has been elected as President of the European Association of Cardiovascular Imaging (EACVI).

Pharmacology success for the WHRI at the Queen Mary Education Excellence Awards and President and Principal’s prize 2020
10 December 2020

We are pleased to announce that Dr Sadani Cooray from the William Harvey Research Institute (WHRI) was recognised for her outstanding contribution to pharmacology education at an online ceremony held on Tuesday 8th December.

Portrait photo of Dr Zahra Raisi-Estabargh Q&A: Repeatability of Cardiac Magnetic Resonance Radiomics: A Multi-Centre Multi-Vendor Test-Retest Study
2 December 2020

A new collaborative study involving researchers at Queen Mary University of London investigates a new image analysis toolkit for MRI scans. In this Q&A Dr Zahra Raisi-Estabragh explains how Radiomics analysis can help us to better diagnose heart disease.

The Effect of Blood Lipids on the Left Ventricle: A Mendelian Randomization Study
18 November 2020

A new study by researchers at Queen Mary University of London demonstrates that bad cholesterol has a direct causal effect in inducing heart disease.

Causal Inference for Genetic Obesity, Cardiometabolic Profile and COVID-19 Susceptibility: A Mendelian Randomization Study
13 November 2020

A new study led by researchers at Queen Mary University of London uses a novel approach to investigate the effects of cardiovascular risk factors on the risk of COVID-19 infection.

Groups of people social distancing in the park. The UK needs a sustainable strategy for COVID-19
10 November 2020

As the UK’s second lockdown gets underway, a group of 79 researchers, public health professionals, and healthcare workers are calling for a sustainable public health strategy for COVID-19.

Rheumatoid arthritis of knee New research predicts whether rheumatoid arthritis patients will respond to treatment
27 October 2020

A new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsiveness to disease modifying anti-rheumatic drugs (DMARDs).

Illustration of a group social distancing Herd immunity in COVID-19 control is a ‘dangerous fallacy’, say authors of open letter
15 October 2020

A group of 80 researchers say that a so-called ‘herd immunity’ approach to managing COVID-19 by allowing immunity to develop in low-risk populations is “a dangerous fallacy unsupported by the scientific evidence”.

Queen Mary researcher recognised in the Queen’s Birthday honours
12 October 2020

Charles Knight, Professor of Cardiology at Queen Mary University of London and Chief Executive of St Bartholomew’s Hospital, has received an OBE for services to the NHS and people with heart disease in the Queen’s birthday honours.

Poor bone quality is linked to poor cardiovascular health
25 September 2020

New research by Queen Mary University of London and the University of Southampton’s Medical Research Council Lifecourse Epidemiology Unit (MRC LEU) has found associations between lower bone mineral density and worse cardiovascular health in both men and women.

Researcher awarded prestigious cardiology prize for MRI discovery
22 September 2020

Dr Nay Aung, an academic clinical lecturer at Queen Mary University of London, has been awarded the Royal Society of Medicine President’s prize for best cardiology PhD project.

ROR2 blockade as a therapy for osteoarthritis
17 September 2020

In a new study, published in the journal Science Translational Medicine, researchers from Queen Mary University of London have developed a prototype drug that can heal cartilage and simultaneously help with pain. In this research Q&A Dr Anne-Sophie Thorup from the Centre for Experimental Medicine and Rheumatology explains why the findings are significant. 

 

 

Specialist centres hold key to keeping heart attack victims alive, major study shows
4 September 2020

A trial led by Queen Mary University of London and Barts Health researchers looking at the effect of stem cell therapy in treating heart attack patients has revealed the importance of specialist centres to extending life.

New molecule repairs cartilage and relieves symptoms of osteoarthritis
3 September 2020

A newly discovered molecule has been found to provide long-lasting regeneration of bone and cartilage defects, as well as symptom relief, and could potentially play a role in treating osteoarthritis, according to early research in animals led by Queen Mary University of London.

Architecture of the heart different between women and men and with age
1 September 2020

Differences in the shape and texture of men and women’s hearts could potentially explain why their risk of heart disease differs, according to research led by Queen Mary University of London.

WHRI COVID Diaries: Q&A with Dr Vanessa Lowe
25 August 2020

In this Q&A WHRI researcher Vanessa Lowe shares her experience of helping with COVID-19 testing at the UK Biocentre in Milton Keynes. 

Metformine prescription pills with identification numbers on blue background Cheap diabetes drug may reverse blood vessel damage and prevent multi-organ failure
22 July 2020

A BHF funded study involving researchers from Queen Mary University of London has found that metformin-a cheap drug commonly used to treat type 2 diabetes- could be used to stop blood vessels from leaking and reverse the damage caused during sepsis and multi-organ failure.

Queen Mary BHF Accelerator Award enables Covid-19 research
16 July 2020

The British Heart Foundation (BHF) has allowed and encouraged institutions that hold Accelerator Awards (AA) to allocate currently uncommitted funds from their award to supporting Covid-19 research, at the discretion of the award director.

Success at the first-ever online WHRI Annual Review
3 July 2020

The first virtual William Harvey Annual Review took place on Wednesday 24th June 2020 on Microsoft Teams.  

Hospital Higher rates of severe COVID-19 in BAME populations remain unexplained
19 June 2020

Higher rates of severe COVID-19 infections in Black, Asian and Minority Ethnic (BAME) populations are not explained by socioeconomic or behavioral factors, cardiovascular disease risk, or by vitamin D status, according to new research led by Queen Mary University of London.

Queen Mary academics win national award recognising exceptional contribution to pharmacology education
15 June 2020

Dr Sadani Cooray and Professor Nick Goulding from Queen Mary University of London have been jointly awarded the Rang Prize 2020 by the British Pharmacological Society.

Antihistamines and similar drugs could slow down Huntington’s disease
9 June 2020

Controlling dopamine signalling by targeting the histamine receptor has been shown to be a promising strategy for preventing the progression of Huntington’s disease in mice.

Scientists discover more than 200 genetic factors causing heart arrhythmias
21 May 2020

Hundreds of new links have been found between people’s DNA and the heart’s electrical activity, according to a study of almost 300,000 people led by researchers at Queen Mary University of London and the Broad Institute of MIT and Harvard.

Discovery of New Genes Modulating the Tpe Interval: an Electrocardiographic risk marker for Sudden Cardiac Death
7 May 2020

Thirty-eight new gene regions that influence the Tpe interval, an electrocardiographic marker associated with susceptibility to malignant ventricular arrhythmias and sudden cardiac death, have been discovered in the largest genetic study to date. 

The uncertainties in modelling the COVID-19 pandemic
1 May 2020

Dr Deepti Gurdasani from Queen Mary’s William Harvey Research Institute and Hisham Ziauddeen from University of Cambridge are co-authors of a correspondence piece in The Lancet Global Health which suggests there were limitations in some assumptions used in the COVID-19 pandemic models forming part of the scientific evidence considered by the UK Government. In this blog post, they explain the importance of real-world evidence being used alongside modelling to develop public health responses.

Predicted Benign and Synonymous Variants in CYP11A1 Cause Primary Adrenal Insufficiency Through Missplicing
1 May 2020

A joint international study led by researchers at QMUL explores how variants that might be overlooked in standard analyses can be pathogenic when combined with much rarer disruptive changes.

Researchers use magnetism to keep drugs at disease sites
30 April 2020

New research from Queen Mary University of London suggests that a novel magnetism-based drug delivery approach could help ensure drugs are not removed from where they are needed in the body.

Inside the lab testing thousands of NHS samples for COVID-19
28 April 2020

Queen Mary University of London has been providing support to the UK Lighthouse Labs Network – the national COVID-19 diagnostic lab network. As well as donating a number of laboratory machines, a team of research staff have been seconded to help test thousands of samples from NHS workers every day.

Dr Neil Dufton, Lecturer in Inflammatory Sciences at Queen Mary’s William Harvey Research Institute, has been volunteering at one of the Lighthouse Labs in Milton Keynes and shares his experiences in this blog post.

Antibodies could provide new treatment for OCD
21 April 2020

Mental health conditions such as obsessive compulsive disorder could be treated in a new way using drugs that target the immune system, research suggests.

Queen Mary and Barts Health launch Covid-19 research programme
20 April 2020

Queen Mary University of London and Barts Health NHS Trust, as part of their Barts Life Sciences initiative, have begun a new programme of Covid-19 research across Barts Health hospitals, including NHS Nightingale Hospital London.

Queen Mary professor to lead new NHS Nightingale Hospital
8 April 2020

Charles Knight, Professor of Cardiology at Queen Mary University of London and Consultant Cardiologist at Barts Health NHS Trust, has been announced as the Chief Executive of the new NHS Nightingale Hospital London.

Diabetes drug reduces complications of long-term steroid therapy
26 February 2020

A drug used to treat type 2 diabetes could offer a simple and cheap solution to reduce dangerous side effects of steroid treatment, new research from Queen Mary University of London suggests.

World first in AI helps predict heart attacks and stroke
14 February 2020

Artificial intelligence has been used for the first time to instantly and accurately measure blood flow, in a new study involving researchers from Queen Mary University of London.

 

International team delivers research breakthrough for leading cause of blindness
7 February 2020

Researchers have identified a new protein linked to age-related macular degeneration (AMD) that could offer new hope for the diagnosis and treatment of the disease, which affects over 1.5 million people in the UK alone.

New research identifies a distinct way to control joint inflammation and arthritis
6 February 2020

In a new study, published in the journal Nature Communications, researchers from Barts and The London School of Medicine and Dentistry at Queen Mary University of London observe that the promotion of synovial fibroblast senescence activates tissue protective mechanisms in the arthritic joint.

Queen Mary Professor in Endocrinology elected to the Hungarian Academy of Medical Sciences
5 February 2020

Professor Márta Korbonits from the William Harvey Research Institute at Queen Mary University of London was recently elected to the Hungarian Academy of Medical Sciences.

Pinpointing rare disease mutations
31 January 2020

A new study from Queen Mary University of London and EMBL’s European Bioinformatics Institute has uncovered the genes essential for supporting life, which could help researchers to identify mutations responsible for rare childhood diseases.

Researchers identify possible link between cannabis use and structural changes to heart
19 December 2019

Regular cannabis use could affect the structure and function of the heart, research led by a team at Queen Mary University of London suggests.

Success for the WHRI at the Queen Mary Education Excellence Awards and President and Principal’s prize
13 December 2019

We are pleased to announce that Dr Parjam Zolfaghari, Professor Nick Goulding and Dr Martin Carrier from Queen Mary’s William Harvey Research Institute (WHRI) were one of several winners at the Queen Mary Education Excellence Award and President and Principal's Prizes for 2019/20.

Researchers look behind the biological curtain on how fish oil might fight inflammatory disease
13 December 2019

The debate about the potential for exploiting omega-3 fatty acids to improve health has raged for years.

Cardiovascular Genomics Professor among most highly cited researchers
26 November 2019

The William Harvey Research Institute is proud to announce that Panos Deloukas, Professor of Cardiovascular Genomics, has been named in the top 0.1% of the world’s most influential researchers.

Researchers find potential new target for treatment of inflammatory disease
8 November 2019

A new joint study involving researchers from Queen Mary University of London has identified potential new targets to tackle lactate-induced chronic inflammation. 

WHRI Emeritus Professor awarded Faculty of Intensive Care Gold Medal
8 November 2019

Professor Charles Hinds recognised for his exceptional contribution to intensive care medicine.

 

Success for WHRI at the International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
5 November 2019

Scientists from 21 countries travelled to St. Petersburg, Florida, USA last week to attend the 16th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, which is sponsored by the Eicosanoid Research Foundation.

Outstanding impact in teaching recognised in national award
5 August 2019

Professor Maralyn Druce from Queen Mary University of London has been announced as a new National Teaching Fellow by Advance HE today.

Health tech start-up partners with the William Harvey Research Institute to develop personalised treatment for high blood pressure
25 July 2019

Closed Loop Medicine (CLM), the Cambridge based therapeutics company that helps doctors and healthcare providers to deliver personalised treatment regimens, has raised £1.3 million in research grant funding from the InnovateUK Innovation Accelerator, Longwall Ventures and IQ Capital. The InnovateUK Innovation Accelerator is a new scheme that enables InnovateUK to match fund a select group of company investors.

WHRI Academic voted 2019 Teacher of the Year by MBBS students
17 July 2019

We are pleased to announce that Dr Fu Liang Ng, Clinical Senior Lecturer in Clinical Pharmacology at the William Harvey Research Institute, was voted Teacher of the Year by the MBBS students for 2019.

2019 WHRI Annual Review Summary
27 June 2019

The William Harvey Annual Review took place on the 12th of June 2019 at the Derek Willoughby Lecture Theatre, Charterhouse Square.

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
25 June 2019

A new joint study involving researchers at Queen Mary University of London has identified background subclinical changes on the electrocardiogram as risk factors in cardiovascular mortality.

EMR delivers “Creating without constraint: Arthritis and art” at QMUL’s Tate Exchange
24 June 2019

The Centre for Experimental Medicine and Rheumatology (EMR) at the William Harvey Research Institute is committed to engaging with the public and has participated in the Barts and Queen Mary Science Festival for a number of years, offering children the opportunity to try gloves that simulate the effect of arthritis and to ‘see’ inside their joints using ultrasound, so when QMUL Arts and Culture asked for proposals for the 2019 Tate Exchange EMR decided to build on this and submit a project.

 

Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Non-Cardiovascular Diseases
11 June 2019

A new study led by researchers at Queen Mary University has shown how genetic predisposition to coronary heart disease (including heart attacks) is genetically correlated to other diseases.

Leading genomics expert awarded knighthood in the Queen’s birthday honours
7 June 2019

Professor Mark Caulfield, the interim Chief Executive at Genomics England and Professor of Clinical Pharmacology at Queen Mary University of London, has been awarded a knighthood in the Queen’s Birthday Honours List.

 

Coffee not as bad for heart and circulatory system as previously thought
3 June 2019

Drinking coffee might keep us up at night, but new research has given us a reason to sleep easy knowing that the popular drink isn’t as bad for our arteries as some previous studies would suggest. The research from Queen Mary University of London has shown that drinking coffee, including in people who drink up to 25 cups a day, is not associated with having stiffer arteries.

Follow us on LinkedIn
30 May 2019

We are pleased to announce that we are now officially on LinkedIn!

DNA discovery could have implications for mitochondrial donation treatment
24 May 2019

Mitochondria, the ‘batteries’ that produce our energy, interact with the cell’s nucleus in subtle ways previously unseen in humans, according to research involving academics from Queen Mary University of London.

London heart disease patients take part in clinical trial to test alternative to statins
20 May 2019

A clinical trial, coordinated by researchers from Queen Mary University of London, is currently recruiting patients in London to see whether a new cholesterol-lowering drug could save lives in people who are intolerant to statins.

Quality Improvement in emergency surgery shows no difference in patient survival
25 April 2019

Researchers from Queen Mary University of London studied the effectiveness of one of the largest ever national quality improvement programmes in the National Health Service (NHS) and found no improvement in patient survival.

Poor lung function in shorter people linked to increased risk of heart disease
28 March 2019

Results from a study led by researchers from Queen Mary University of London has found that an association between shorter stature and higher risk of heart disease is mainly attributed to our lungs.

QMUL researchers seek treatment for arthritis as part of new EU-funded project
14 March 2019

Researchers from Queen Mary University of London are about to start work on a new EU-funded project to discover novel therapeutic targets for osteoarthritis and rheumatoid arthritis.

QMUL researchers win prestigious award for Vascular Biology publication
7 March 2019

A publication by researchers from the Centre for Microvascular Research at the William Harvey Research Institute has received the highly prestigious Servier Award in Microcirculation.

BHF invests £34m in top universities, helping to safeguard UK’s world-class research status
6 March 2019

The British Heart Foundation (BHF) has this week announced £34million of new funding across 12 universities, in a move that strengthens world-class, UK-led heart and circulatory disease research.

Working long hours linked to depression in women
26 February 2019

Women who work more than 55 hours a week are at a higher risk of depression compared to men, according to a UCL-led study with Queen Mary University of London.

Professor of Endocrine Medicine achieves recognition for Excellence in Education
22 February 2019

The winners of Queen Mary’s new scheme of annual Education Excellence Awards and President and Principal’s Prizes were announced at a ceremony on 20 February 2019

Researcher named as one of the most inspirational women in science
15 February 2019

Professor Federica Marelli-Berg from Queen Mary University of London has been named by the British Heart Foundation (BHF) as one of the top 10 inspirational women in science.

Genomics project reaches goal of 100,000 genomes sequenced from NHS patients
6 December 2018

UK Health Secretary Matt Hancock has today announced that a project involving Queen Mary University of London researchers has reached its goal of sequencing 100,000 whole genomes from NHS patients.

WHRI researchers in top 1 per cent worldwide
27 November 2018

Three researchers from the William Research Institute have been placed in the top 1 per cent in the world, in this year’s Highly Cited Researchers list.

Research in Focus
22 November 2018

Dr Gloria Lliso-Ribera, Rheumatology Clinical Research Fellow

Professor Chris Thiemermann honoured for his contributions to science
8 November 2018

In October 2018, Chris Thiemermann, Professor of Pharmacology and Centre Lead for Translational Medicine & Therapeutics at the William Harvey Research Institute, received the prestigious Albert Nelson Marquis Lifetime Achievement Award.

Professor Márta Korbonits delivers inaugural Lady Estelle Wolfson lecture at the RCP
29 October 2018

Professor Márta Korbonits gave the Lady Estelle Wolfson lecture in translational medicine at the Royal College of Physicians on the 24th October 2018 during the Acute and General Medicine Conference.

Genetic tool to predict adult heart attack risk in childhood
10 October 2018

People at high risk of a heart attack in adulthood could be identified much earlier in life with a one-off DNA test, according to new research published in the Journal of the American College of Cardiology.

Landmark TB research announced at the UN General Assembly
27 September 2018

A landmark international research project, involving researchers from Queen Mary University of London, has shown that we can now use our knowledge of the tuberculosis (TB) genetic code to predict which drugs are best for treating a patient’s infection.

Researchers awarded for lifetime achievements in blood pressure research
24 September 2018

Two academics from Queen Mary University of London have received prestigious awards from the International Society of Hypertension (ISH) in recognition of their achievements in blood pressure research.

Study of one million people leads to world’s biggest advance in blood pressure genetics
17 September 2018

Over 500 new gene regions that influence people’s blood pressure have been discovered in the largest global genetic study of blood pressure to date, led by Queen Mary University of London and Imperial College London.

Blood pressure medications and statins found to provide long-term cardiovascular benefits
28 August 2018

Death rates from heart disease and stroke could be significantly lowered by prescribing statins alongside blood pressure-lowering drugs, according to the results from a clinical trial led by Queen Mary University of London and Imperial College London.

New research links low levels of air pollution with serious changes in the heart
3 August 2018

Researchers from Queen Mary University of London have found that people exposed to air pollution levels well within UK guidelines have changes in the structure of the heart, similar to those seen in the early stages of heart failure.

ESE’s Scientific Programme Chair discusses Brexit effects on European Reference Network in the UK Parliament
6 July 2018

Professor Márta Korbonits, Professor of Endocrinology at Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Scientific Programme Chair of the European Society of Endocrinology, and representative of BioMed Alliance, will be discussing the effects of Brexit on the European Reference Networks (ERNs), in Westminster, Monday 9 July.

Q&A with Dr Li Chan
7 June 2018

Research paper: MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation

New lab technology could reveal treatments for muscle-wasting disease
6 June 2018

Researchers from Queen Mary University of London have developed new cell-based technologies which could improve understanding of the muscle-wasting disease Duchenne muscular dystrophy (DMD) and test potential drugs for the disease.

Surgery involving ultrasound energy found to treat high blood pressure
23 May 2018

An operation that targets the nerves connected to the kidney has been found to significantly reduce blood pressure in patients with hypertension, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR).

Lunch & Learn: Cutting Edge Studies in Autoimmune Disease
18 May 2018

Date: 1 June 2018
Time: 12:00pm
Venue: William Harvey Research Institute, Charterhouse Square Campus

QMUL and UCL joint study identifies genes linked to impaired capacity to modulate heart rate during and after exercise
17 May 2018

A new study by researchers at Queen Mary University of London (QMUL) and University College London (UCL) has discovered 30 new gene locations that determine how the heart responds to and recovers from exercise.

Fellows inaugurated at new Rutherford Academy of Population Genomics and Health Data Science
14 May 2018

Queen Mary University of London has appointed four postdoctoral research fellows to its new Rutherford Academy of Population Genomics and Health Data Science, funded by the Medical Research Council and UK Research and Innovation’s Rutherford Fund. One of the fellows include WHRI's Dr Adriano Barbosa.

Professor Panos Deloukas elected as Fellow of The Academy of Medical Sciences
10 May 2018

Professor of Cardiovascular Genomics at Queen Mary University of London has been recognised for his outstanding contribution to genomic medicine. 

Professor Gustav Born: 29th July 1921- 16 April 2018
25 April 2018

A message sent on behalf of Professor Steve Thornton, Vice Principal (Health)

Pint of Science Festival, 14-16 May 2018
13 April 2018

Pint of Science QMUL brings scientists out of the lab and in to your local pub.

Hormone imbalance causes treatment-resistant hypertension
12 April 2018

British researchers have discovered a hormone imbalance that explains why it is very difficult to control blood pressure in around 10 per cent of hypertension patients.

New project to transform treatment for children with arthritis
28 March 2018

Researchers from Queen Mary University of London will join a UK-wide effort to drive the development of new treatments for children and young people with juvenile idiopathic arthritis (JIA) and its associated eye-inflammation condition, uveitis.

Weak hand grip could be sign of a failing heart
15 March 2018

Hand grip strength could be used as a simple measure of heart health, according to new research led by scientists at Queen Mary University of London.

Menopausal hormone therapy linked to having a healthier heart
9 March 2018

Women who use menopausal hormone therapy appear to have a heart structure and function that is linked to a lower risk of heart failure, according to a study led by Queen Mary University of London.

New insights into why patients have a higher risk of heart attack in the morning
8 March 2018

Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.

Aspirin helps treat tuberculous meningitis
7 March 2018

The painkiller aspirin appears to reduce the risk of stroke and death in patients with the most deadly form of tuberculosis, according to a study by Queen Mary University of London, Oxford University Clinical Research Unit (Vietnam), Western General Hospital and University of Oxford.

Isolated white blood cell packages from patients with rheumatoid arthritis shown to be protective against inflammation
1 March 2018

A new study by researchers from Queen Mary University of London finds that small packages released by white blood cells during inflammation can be used to prevent the activation of other white blood cells.  

Dr Suchita Nadkarni's 'The Placenta Rainbow' featured in National Geographic
27 February 2018

Photo by William Harvey Research Institute (WHRI) and British Heart Foundation (BHF) Research Fellow shows differences in mouse placental development that can result from manipulation of the mother’s immune system.

“Beetroot pill” could help save patients from kidney failure after heart x-ray
22 February 2018

Beetroot may reduce the risk of kidney failure in patients having a heart x-ray, according to research led by Queen Mary University of London.

£54 million award to transform health through data science
7 February 2018

Queen Mary University of London has partnered with four other London universities - UCL, Imperial College London, King's College London and The London School of Hygiene & Tropical Medicine - in a new initiative to transform health through data science.

100,000 Genomes Project to sequence its 500th genome later this month
6 February 2018

Professor Mark Caulfield spoke to Observer Science Editor Robin McKie about the pioneering work of the 100,000 Genomes Project as it approaches its halfway point.

Multinational companies continue to produce unregulated antibiotics in India
6 February 2018

Millions of unapproved antibiotics are being sold in India, according to a new joint study led by Dr Patricia McGettigan from the William Harvey Research Institute.

The first step in generating an artificial adrenal gland
31 January 2018

In a new study, published in Cell Reports, researchers from Queen Mary University of London used cells derived from urine to take the first step in generating an artificial adrenal gland, which could help develop future treatments for adrenal gland disorders.

Diabetes gene found that causes low and high blood sugar levels in the same family
16 January 2018

A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.

 

Chemically modified insulin as a new marker to identify type 1 diabetes
15 November 2017

A technique that could help predict, diagnose, stage and treat type 1 diabetes is currently being developed by researchers at the William Harvey Research Institute, Queen Mary University of London

CHIAROSCURO from War Crime Trials to Clinical Trials
20 July 2017

Date: Tuesday 25 July 2017 at 7:30 pm 
Location: The Great Hall of St Bartholomew's Hospital, West Smithfield, London EC1 7BE

A new hope for reducing uncontrollable blood pressure
12 July 2017

At The Royal London Hospital, on 30 June 2016, the Barts Blood Pressure Clinic became the first hospital in the country to provide two NHS patients with the innovative Barostim Neo™ device that could transform and save the lives of people living with uncontrollable blood pressure. 

Genetic testing can pick out men at increased risk of testicular cancer
13 June 2017

Testing for large numbers of genetic changes can identify men with over a 10-fold increased risk of testicular cancer, a new study shows. Researchers found that testing for newly identified genetic factors along with others found in their previous studies could pick out men at increased risk, who might potentially benefit from monitoring or preventative treatment.

Statins help improve heart structure and function
1 June 2017

Statins can improve the structure and function of the heart, according to a new study by researchers at Queen Mary University of London (QMUL)

QMUL study finds link between diesel pollution and heart damage
1 June 2017

Diesel fumes have negative effects on the heart according to a new study by researchers at Queen Mary University of London (QMUL). 

New study finds loss of Sacsin effects organisation of the cells cytoskeleton
30 May 2017

ARSACS Foundation funded scientists at Queen Mary University of London, McGill University and Università Vita-Salute San Raffaele have just published a research paper in the journal Human Molecular Genetics, which looks at the cytoskeleton in cells cultured from ARSACS patients.

Data strongly suggests that the brain controls exercise capacity
18 May 2017

A joint study by researchers from Queen Mary University of London (QMUL), University College London (UCL) and the University of Bristol suggests that the brain controls exercise capacity, a highly novel idea with ramifications for health in the general population as well as elite athletes.

Some statin-related side-effects are due to 'nocebo' effect
3 May 2017

Patients report more side effects when they know they are taking a statin, than when they do not know whether they are on the drug or a dummy pill, according to a study by researchers from Imperial College London and Queen Mary University of London (QMUL)

Research Matters - changing lives in east London and beyond
13 April 2017

Date: Wednesday 24 May, 5pm - 7.30pm
Location: Perrin Lecture Theatre, Blizard Institute, 4 Newark Street, London E1 2AT

 

Success for WHRI at QMUL Engagement and Enterprise Awards 2017
3 March 2017

On Tuesday 7th February 2017 QMUL hosted the second annual Engagement and Enterprise Awards to celebrate and showcase projects demonstrating excellence in the application and dissemination of research and teaching through public engagement, academic innovation, media relations and student enterprise.

Genetic defect found to cause disease in multiple organs
7 February 2017

New research from Queen Mary University of London (QMUL) has identified a novel syndrome in patients with kidney and adrenal disease.

William Harvey New Year Celebration 2017
7 February 2017

On Friday the 3rd of February the WHRI held its annual New Year Celebration and featured 15 talks from the institute's postgraduates and young post-docs.

William Harvey Research Institute hosts Church of England clergy visits
2 February 2017

Church of England vicars visit the WHRI to experience clinical and genomic research at first hand, as part of a national initiative to help scientists and faith leaders engage in dialogue and enhance understanding of ethical issues in medicine.

Professor Fulvio D'Acquisto receives large CPE award for a project titled 'CPD course to establish the Young Mind Science Knowledge Network'
27 January 2017

East London school teachers to be provided CPD support and workshops to connect local schools with the Frontiers for Young Minds initiative, an open access scientific journal that publishes ground‐breaking science in language reviewed by teachers and their classes for accessibility.

Research summary: Enzymes responsible for tissue repair
11 October 2016

Dr Jesmond Dalli explains how his new research has uncovered enzymes that are crucial for the repair and regeneration of tissues, and could lead to new treatments for diseases such as rheumatoid arthritis.  

WHRI researchers identify link between immunity and 'holidays'
30 September 2016

A team of researchers at the WHRI are investigating ways in which holidays, music or a change of environment can bolster our immune systems in the fight against disease

Major global study reveals new hypertension and blood pressure genes
13 September 2016

Thirty-one new gene regions linked with blood pressure have been identified in one of the largest genetic studies of blood pressure to date, involving over 347,000 people, and jointly led by Queen Mary University of London (QMUL) and the University of Cambridge. 

WHRI on now the UK pharmacology map
15 December 2015

'UK Pharmacology on the Map' award was presented to the WHRI for its outstanding contribution to the discovery and development of medicines.