Professor Rupert Pearse
NIHR Professor of Intensive Care Medicine
Centre: Translational Medicine and Therapeutics
Email: r.pearse@qmul.ac.ukTelephone: +44(0) 20 3594 0351Twitter: @rupert_pearse
Profile
ORCID iD: 0000-0002-4373-5934
Rupert Pearse graduated in 1996 from St George’s Hospital Medical School, London, UK. He also completed much of his clinical training in the south-west Thames region. His clinical duties are based on the busy Adult Critical Care Unit at the Royal London Hospital where he oversees the care of patients with critical illnesses of various causes. In 2006, Rupert was appointed Senior Lecturer in Intensive Care Medicine at Queen Mary University of London and was promoted to Professor in 2014. He is an active member of several national and international societies for anaesthesia and intensive care medicine. He leads the Critical Care and Perioperative Medicine Research Group. Rupert’s main research interest is in improving patient outcomes following major surgery, and has led numerous large multi-centre randomised trials, epidemiological studies and mixed-methods research projects in his field.
Research
Group members
Critical Care and Perioperative Medicine Research Group
Summary
My research is focused on improving the care pathway for patients before, during and after major surgery. This includes the study of risk factors for poor health, interventions during surgery which may improve patient outcomes, through to better ways to make decisions about surgical treatments together with patients. Increasingly, my work involves the care of patients who need surgical treatments in low and middle-income countries as well as high-income countries.
Publications
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Group PTM, Ademuyiwa A, Bhangu A et al. (2025). PErioperative respiratory care aNd outcomes for patients underGoing hIgh risk abdomiNal surgery (PENGUIN): a randomised international internal pilot trial. nameOfConference
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Alvarez A, Bagshaw S, Biccard B et al. (2025). Patient outcomes after surgery in 17 Latin American countries (LASOS): a 7 day prospective cohort study. nameOfConference
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Harji DP, Griffiths B, Stocken D et al. (publicationYear). Key interventions and outcomes in perioperative care pathways in emergency laparotomy: a systematic review. nameOfConference
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Baker T, Scribante J, Elhadi M et al. (2025). The African Critical Illness Outcomes Study (ACIOS): a point prevalence study of critical illness in 22 nations in Africa. nameOfConference
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Hewitt-Smith A, Bulamba F, Patel A et al. (2025). Corrigendum to ‘Family supplemented patient monitoring after surgery (SMARTER): a pilot stepped-wedge cluster-randomised trial’ (Br J Anaesth 2024; 133: 846–52). nameOfConference
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Pinto BB, Shelley B, Dias P et al. (2025). Targeted heart rate control using the funny current inhibitor ivabradine to reduce morbidity in patients undergoing noncardiac surgery: study protocol for a phase 2a, triple-blind, placebo-controlled randomised trial. nameOfConference
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Abani O, Abbas A, Abbas F et al. (2025). Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial. nameOfConference
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Lloyd P, Fowler AJ, Wozniak A et al. (2025). Environmental impact of commonly used anaesthetic agents: systematic literature review with narrative synthesis. nameOfConference
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Ackland G (publicationYear). Preoperative activation of the renineangiotensin system and myocardial injury in noncardiac surgery: exploratory mechanistic analysis of the SPACE randomised controlled trial. nameOfConference
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Pearse R, Hamborg T (2024). Cardiac output-guided haemodynamic therapy for patients undergoing major gastrointestinal surgery: the OPTIMISE II randomised clinical trial.. nameOfConference