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Professor Anthony Mathur

Anthony

Centre for Cardiovascular Medicine and Devices - Centre Lead

Centre: Cardiovascular Medicine and Devices

Email: a.mathur@qmul.ac.uk
Telephone: +44(0) 20 3765 8740

Profile

I divide my time equally between clinical work and translational medicine and research. My research focuses on examining the role of biologics (stem cells, gene therapy, cellular bioenergetics, megakaryocyte biology) in the treatment of cardiovascular disease. As the Clinical Director for Interventional Cardiology at Barts Health, my clinical work is directed towards the management of patients who have failed conventional therapy for heart failure and angina. Furthermore, I Chair the ESC Task Force on stem cells in cardiovascular disease and, previously, I Chaired the British Cardiac Stem Cells Collaborative set up by Prof. John Martin. I also lead the Compassionate Stem Cell Treatment Unit for patients with cardiac disease at Barts Heart Centre.

Within the Centre for Cardiovascular Medicine and Devices, I lead the Cardiovascular Devices Hub (CVD HUB). The CVDHub supports collaborations between academic, clinical, engineering and industrial innovators to develop clinically and commercially viable cardiovascular devices. This novel, cross-speciality unit helps small to medium enterprises (SMEs) over the hurdles involved in taking innovations to human trials. Within device innovation, I focus on first-in-man trials, digital technologies (e.g Avatars) and artificial intelligence.

Research

I lead a collaborative group with several investigators (including Prof. John Martin (UCL), Prof. Amrita Ahluwalia (Queen Mary), Prof. Andreas Baumbach (Queen Mary) and Prof. Alexandra Lansky (Yale) seeking to address the role of biologics in the treatment of cardiovascular disease; translating basic research into therapeutic approaches in man. My interventional cardiology research aims to develop new treatments for patients that fall outside the remit of current recognised therapies. I have designed a series of trials addressing the use of stem cells in the treatment of cardiovascular disease, and am currently the CI for one of the first Phase III clinical trials of cell therapy in acute myocardial infarction. I am also interested in the use of advanced cardiac imaging, and established the first Cardiac CMR service at Barts Health.

Publications

  • Mehta V, Poply K, Choudhry F et al. (2026). ID# 2198423 NATIONAL JOINT CARDIOLOGY AND NEUROMODULATION MULTIDISCIPLINARY SERVICE FOR REFRACTORY ANGINA MANAGEMENT. nameOfConference


    QMRO: qmroHref
  • Jones J, Coldea B, Butt H et al. (2026). Peak apical rotation independently predicts left ventricular thrombus following anterior myocardial infarction. nameOfConference


    QMRO: qmroHref
  • Bevis L, Rauseo E, Hebda-Boon A et al. (2026). Clinical perspectives on the virtual human twin: an overview of engagement and adoption challenges.. nameOfConference


    QMRO: qmroHref
  • Ramaseshan R, Hussain M, Perera D et al. (2026). Procedural circulatory support-enabled intracoronary cell delivery in advanced dilated cardiomyopathy. nameOfConference


    QMRO: qmroHref
  • Jin Y, Pepe A, Melito GM et al. (2027). Automatic segmentation and modeling of the aortic vessel tree: Overview of the SEG.A 2023 aorta segmentation challenge. nameOfConference


    QMRO: qmroHref
  • Bhatti Y, Yazdi A, Jones DA et al. (publicationYear). The detection of cardiovascular biomarkers in dermal interstitial fluid - a step to real-time monitoring. nameOfConference


    QMRO: qmroHref
  • Bajaj R, Wan MYS, Thielemans K et al. (publicationYear). From incidental positron emission uptake to in-vivo phenotyping: a short history of positron emission tomography in the study of atherosclerosis and the vulnerable plaque. nameOfConference


    QMRO: qmroHref
  • Rayner T, Rathod K, Mathur A et al. (2026). 39 Improving outcomes for patients after venous graft percutaneous coronary intervention: is there a role for computerised tomography coronary angiography?. Imaging


    QMRO: qmroHref
  • Sullivan AJ, Tun Z, Siu M et al. (2026). Narrowing sex differences in pharmacotherapy following invasive angiography for coronary artery disease between 2017 and 2024. nameOfConference


    QMRO: qmroHref
  • Rauseo E, Bevis L, Chen X et al. (publicationYear). Computational modelling for personalized transcatheter aortic valve replacement planning: a systematic review of complications and decision support. nameOfConference


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Disclosures

I disclose the following relevant interests from the past 3 years:

  • Board Member - IoNa Therapeutics: Company number 15704565
  • Board Member - Heart Cells Company: Company number 10282577
  • Inventor on US Patent No. 11,191,877 - 'Magnetised Coronary Stent'
  • Inventor on Japanese Patent No. 6650930 - 'Stem Cell Delivery Method'
  • Inventor on UK Patent Application No.2508620: Method for managing blood pressure
  • Inventor on UK Patent Application No. 2411474.6: “Medical Support Method” describing a pipeline for TAVR digital twin simulation.
  • Inventor on International Patent application PCT/GB2025/051004 - Method for selection of cells with reparative potential
  • 2004-Present: Trustee of the Heart Cells Foundation Charity
  • 2025: Honoraria  - Advisory Board for Abbott

 

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