Dr Nikos Mardas, Dipl DS, MS, PhD, Specialist in Periodontics
Clinical Reader in Periodontology, Undergraduate Periodontology Lead
Email: n.mardas@qmul.ac.uk Telephone: +44 (0) 20 7882 2608Room Number: Office 11, Floor 4, Institute of Dentistry
Profile
Dr Nikos Mardas qualified in Dentistry from Athens University in 1992. He completed his 3-year specialist training and MS degree in Periodontology in 1997 at the Royal Dental College, University of Aarhus, Denmark. He was awarded a PhD degree in 2005 from the same University.
During the period 2005-2015 he was a Senior Lecturer / Honorary Specialist and MClinDent program co-ordinator in Periodontology Unit, at UCL, Eastman Dental Institute. In July 2015, he was appointed Senior Clinical Lecturer & Honorary Consultant in the Centre for Adult Oral Health, Barts & The London School of Dentistry, Queen Mary University of London. Dr Mardas is also consultant Periodontist and implant surgeon in private practice.
Dr Mardas has published several papers in national and international peer-reviewed journals in the field of periodontal, bone regeneration and implant dentistry and he is editorial board member in Clinical Oral Implant Research and regular reviewer for many international and national journals. He has participated as a reviewer in consensus meetings of EAO, EFP and EADE and has extensively lectured nationally and internationally. In 2011 Dr Mardas was awarded the Basic Research Prize, of the European Association for Osseointegration. In March 2015 was appointed Education Delegate for the UK & Ireland ITI section.
Dr. Mardas has more than 20 years of private practice and University / Hospital based clinical experience in treatment of periodontal diseases including conventional and regenerative periodontal surgery, periodontal plastic surgery, alveolar bone augmentation procedures and dental implants alone or in combination with bone grafting procedures.
Research
Research Interests:
His main research interests are in the area of periodontal, bone and gingival tissue regeneration and wound healing, utilising various biomaterials. He has also a special interest on the outcome of the above mentioned treatment principles in specific systemic conditions like osteoporosis. In the last 10 years, he has been actively involved in several research projects, including in vitro biomaterial testing and development, preclinical - animal experimental projects and randomised clinical trials, evaluating the effectiveness of new regenerative materials for bone and periodontal regeneration, as well as dental implant related treatment protocols.
His current and future research is focusing on:
The evaluation of current bone and periodontal tissue regeneration and implant protocols in healthy or compromised healing conditions by means of preclinical and clinical studies
The development of tissue regeneration protocols based on the combination of novel biomaterials / scaffolds for growth factor, cell or chemotherapeutics delivery
The evaluation of different types of periodontal surgery in terms of clinical, microbiological and patient based outcome
The creation of a sound scientific link between in-vitro studies, pre-clinical animal experiments and initial clinical trials for the treatment of peri-implantitis
The systematic evaluation and analysis of the literature in the field of periodontal and bone regeneration and implant outcomes
Publications
1: Donos N, Horvath A, Calciolari E, Mardas N. Immediate provisionalization of bone level implants with a hydrophilic surface. A five-year follow-up of a randomized controlled clinical trial. Clin Oral Implants Res. 2018 Dec 25. doi: 10.1111/clr.13400. [Epub ahead of print] PubMed PMID: 30584682. (P, C, A, E)
2: Jung RE, Al-Nawas B, Araujo M, Avila-Ortiz G, Barter S, Brodala N, Chappuis V,Chen B, De Souza A, Almeida RF, Fickl S, Finelle G, Ganeles J, Gholami H,Hammerle C, Jensen S, Jokstad A, Katsuyama H, Kleinheinz J, Kunavisarut C, Mardas, N, Monje A, Papaspyridakos P, Payer M, Schiegnitz E, Smeets R, Stefanini M, Ten Bruggenkate C, Vazouras K, Weber HP, Weingart D, Windisch P. Group 1 ITI Consensus Report: The influence of implant length and design and medications onlinical and patient-reported outcomes. Clin Oral Implants Res. 2018 Oct;29 Suppl 16: 69-77.doi: 10.1111/clr.13342. PubMed PMID: 30328189. (E)
3: Dereka X, Calciolari E, Donos N, Mardas N. Osseointegration in osteoporotic-like condition: A systematic review of preclinical studies. J Periodontal Res. 2018 Dec;53(6):933-940. doi: 10.1111/jre.12566. Epub 2018 May 30. Review. PubMed PMID: 29845622. (P, A, E)
4: Calciolari E, Ravanetti F, Strange A, Mardas N, Bozec L, Cacchioli A, Kostomitsopoulos N, Donos N. Degradation pattern of a porcine collagen membrane in an in vivo model of guided bone regeneration. J Periodontal Res. 2018 Jun;53(3):430-439. doi: 10.1111/jre.12530. Epub 2018 Feb 15. PubMed PMID: 29446096. (P, C, A, E)
5: Graziani F, Karapetsa D, Mardas N, Leow N, Donos N. Surgical treatment of the residual periodontal pocket. Periodontol 2000. 2018 Feb;76(1):150-163. doi:10.1111/prd.12156. Epub 2017 Nov 29. Review. PubMed PMID: 29193404. (A, E)
6: Calciolari E, Mardas N, Dereka X, Anagnostopoulos AK, Tsangaris GT, Donos N. Protein expression during early stages of bone regeneration under hydrophobic and hydrophilic titanium domes. A pilot study. J Periodontal Res. 2018 Apr;53(2):174-187. doi: 10.1111/jre.12498. Epub 2017 Oct 24. PubMed PMID: 29063586. (P, C, E)
7: Donos N, Horvath A, Mezzomo LA, Dedi D, Calciolari E, Mardas N. The role of immediate provisional restorations on implants with a hydrophilic surface: A randomised, single-blind controlled clinical trial. Clin Oral Implants Res. 2018 Jan;29(1):55-66. doi: 10.1111/clr.13038. Epub 2017 Aug 21. PubMed PMID: 28833613. (P, C, A, E)8:
8. Sousa, V; Nibali, L; Spratt, D; Dopico, J; Mardas, N; Petrie, A; Donos, N; (2017) Peri‐implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study. Clinical Oral Implants Research , 28 (5) pp. 558-570. 10.1111/clr.12834.
9: Calciolari E, Donos N, Mardas N. Osteoporotic Animal Models of Bone Healing: Advantages and Pitfalls. J Invest Surg. 2017 Oct;30(5):342-350. doi:10.1080/08941939.2016.1241840. Epub 2016 Dec 8. Review. PubMed PMID: 27929692. (P, C, A, E)
10: Calciolari E, Mardas N, Dereka X, Anagnostopoulos AK, Tsangaris GT, Donos N. The effect of experimental osteoporosis on bone regeneration: part 2, proteomics results. Clin Oral Implants Res. 2017 Sep;28(9): e135-e145. doi:10.1111/clr.12950. Epub 2016 Sep 1. PubMed PMID: 27580862. (P, C, E)
11: Calciolari E, Mardas N, Dereka X, Kostomitsopoulos N, Petrie A, Donos N. The effect of experimental osteoporosis on bone regeneration: Part 1, histology findings. Clin Oral Implants Res. 2017 Sep;28(9): e101-e110. doi:10.1111/clr.12936. Epub 2016 Aug 8. PubMed PMID: 27502355. (P, C, E)
12: MacBeth N, Trullenque-Eriksson A, Donos N, Mardas N. Hard and soft tissue changes following alveolar ridge preservation: a systematic review. Clin Oral Implants Res. 2017 Aug;28(8): 982-1004.doi: 10.1111/clr.12911. Epub 2016 Jul 26. Review. PubMed PMID: 27458031. (P, C, A, E)
13: Mardas N, Busetti J, de Figueiredo JA, Mezzomo LA, Scarparo RK, Donos N. Guided bone regeneration in osteoporotic conditions following treatment with zoledronic acid. Clin Oral Implants Res. 2017 Mar;28(3):362-371. doi: 10.1111/clr.12810. Epub 2016 Feb 26. PubMed PMID: 26920844. (P, C, A, M, E)
14: Sousa V, Mardas N, Spratt D, Boniface D, Dard M, Donos N. Experimental models for contamination of titanium surfaces and disinfection protocols. Clin Oral Implants Res. 2016 Oct;27(10): 1233-1242.doi: 10.1111/clr.12735. Epub 2016 Feb 10. PubMed PMID: 26864128. (P, C, A, E)
15: Sousa V, Mardas N, Farias B, Petrie A, Needleman I, Spratt D, Donos N. A systematic review of implant outcomes in treated periodontitis patients. Clin Oral Implants Res. 2016 Jul;27(7):787-844. doi: 10.1111/clr.12684. Epub 2015 Sep 18. Review. PubMed PMID: 26381260. (P, A, E)
Full list of publications can be found at:
https://www.ncbi.nlm.nih.gov/pubmed/?term=Mardas+N