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Blizard Institute - Faculty of Medicine and Dentistry

Professor Xavier Griffin, BA (Hons), PhD (Medicine), FRCS (Tr & Orth),


Chair of Bone and Joint Health

Email: PA, Lauren Exell:
Twitter: @xlgriffin


Professor Xavier Griffin spearheads academic orthopaedics at Queen Mary and Barts Health, having joined in August 2020 as the inaugural chair of Bone and Joint Health.

Xavier’s vision is for world-class excellence in research and clinical academic training; providing opportunity for the next generation of clinician scientists to realise their aspirations.

Xavier has been awarded over £10m of research funding and over 80 peer reviewed publications.

He is driven by having meaningful impact on patient care; his research is focused on the clinical and cost effectiveness of new and existing treatments to improve bone and joint health and has been cited by the National Institute of Clinical Excellence. He has a passion for developing methodologies which harness the speed, power and efficiency of routinely-collected data but are coupled with the great advantages of randomisation.

Xavier’s clinical expertise is orthopaedic trauma surgery specialising in pelvic and acetabular fractures. He enjoys working as part of the team at the busiest orthopaedic trauma hospital in Europe – The Royal London. Having graduated from the University of Cambridge in 1999 before attending medical school at the University of Oxford, Xavier trained in orthopaedic surgery as a National Institute of Health Research integrated clinical academic fellow. Xavier completed a world-renowned clinical fellowship in Melbourne, Australia specialising in complex fractures of the pelvis and hip.

Xavier serves in HM Reserve Forces, outside of work Xavier can be found mountain biking or rock climbing usually with his young sons in tow!


Research Interests:

  • Priority Setting Partnership in Major Trauma
  • Improving Ethnic Representation Within The Tendon Human Cell Atlas
  • Fix or Replace Undisplaced Intracapsular fractures Trial of Interventions
  • Cochrane Systematic Review Programme in Hip Fracture
  • Changes in treatments and outcomes of open fractures – ‘before’ and ‘after’ MTCs were established
  • Fractured Ankle Management Evaluation
  • World Hip Trauma Evaluation 9 – Blood Cell Salvage Trial
  • Weight-bearing in ankle fractures
  • Mapping Barts Health NHS Trust electronic health record to the OMOP data model
  • World Hip Trauma Evaluation
  • Mapping the FFN international collaboration of hip fracture registries to the OMOP data model


Read more about Bone and Joint Health’s research


Key Publications

Griffin XL, Parsons N, Costa ML, Metcalfe D. Ultrasound and shockwave therapy for acute fractures in adults. Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No.: CD008579

Griffin XL, Parsons N., Achten J., Fernandez M., and Costa ML. Recovery of health-related quality of life in a United Kingdom hip fracture populationThe Bone & Joint Journal 2015 97-B:3, 372-382

Smith TO, Gilbert AW, Sreekanta A, Sahota O, Griffin XL, Cross JL, Fox C, Lamb SE. Enhanced rehabilitation and care models for adults with dementia following hip fracture surgery. Cochrane Database of Systematic Reviews 2020, Issue 2. Art. No.: CD010569.

Sedina Lewis, Jessica Glen, Dalia Dawoud, Sofia Dias, Jill Cobb, Xavier Griffin, Michael Reed, Carlos Sharpin, Gerard Stansby, Peter Barry. Venous Thromboembolism Prophylaxis Strategies for People Undergoing Elective Total Hip Replacement: A Systematic Review and Network Meta-Analysis. Value in Health 2019, Volume 22, Issue 8, 953-969,

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