NIHR funding of £5 million awarded to Tower Hamlets Council and its partners, including QMUL, will establish a Health Determinants Research Collaboration, which will support research on health inequalities. Tower Hamlets has several poorer than average health outcomes and significant variation in these outcomes exists, particularly by deprivation and ethnicity. The funding bid, led by Trevor Sheldon, builds on the strong partnership between WIPH and the Council, established through Act Early. Carol Dezateux will work with the Council to unlock the potential of linked health and council data to examine wider determinants of health, and address health inequalities. Initial work will focus on housing and household overcrowding, and on the Council’s extended free school meals offer. Co-production and involvement of residents is central, and Megan Clinch will support the approach to public involvement and engagement and alignment with QMUL funding, to develop community researchers, working with Alison Blunt and the Centre for Public Engagement.