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School of Physical and Chemical Sciences

Professor Marina Resmini

Marina

Professor of Materials Chemistry

Email: m.resmini@qmul.ac.uk
Telephone: +44 (0)20 7882 3268
Room Number: Room 1.05, Joseph Priestley building

Undergraduate Teaching

  • Advanced Practical Chemistry 1 (CHE301)
  • Professional Skills for Chemists (CHE401)
  • Advanced Biological Chemistry (CHE402)
  • Drug Design and Development (CHE406U)

Research

Research Interests:

The main research interests of our group are currently focused on the development of novel functional nanomaterials with potential applications at the physical and life sciences interface. We use chemistry to confer special properties to materials to be used as drug delivery systems, catalysts and sensors.

In the area of drug delivery our clinical targets are cutaneous diseases, hair follicles and neural stem cells. In catalysis we are researching novel biomimetic systems by applying the molecular imprinting approach to different formats of nanoparticles. We have recently started working on the development of novel sensors for the detection and quantification of key components in coffee.

Research Department

Publications

  • Anastasiadi RM, Berti F, Colomban S et al. (2021). Simultaneous quantification of antioxidants paraxanthine and caffeine in human saliva by electrochemical sensing for CYP1A2 phenotyping. nameOfConference


    QMRO: qmroHref
  • Jones JI, Vdovchenko A, Cooling D et al. (2020). Systematic Analysis of the Relative Abundance of Polymers Occurring as Microplastics in Freshwaters and Estuaries. nameOfConference


  • Judah HL, Liu P, Zarbakhsh A et al. (2020). Influence of buffers, ionic strength, and ph on the volume phase transition behavior of acrylamide-based nanogels. nameOfConference


    QMRO: qmroHref
  • Tommasini M, Pellizzoni E, Iacuzzi V et al. (2020). Fluorescent imprinted nanoparticles for the effective monitoring of irinotecan in human plasma. nameOfConference


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  • Rose RS, Richardson KH, Latvanen EJ et al. (2020). Microbial degradation of plastic in aqueous solutions demonstrated by Co2 evolution and quantification. nameOfConference


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  • Monteiro Â, Colomban S, Azinheira HG et al. (2020). Dietary antioxidants in coffee leaves: Impact of botanical origin and maturity on chlorogenic acids and xanthones. nameOfConference


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  • Pearce CM, Resmini M (2020). Towards point of care systems for the therapeutic drug monitoring of imatinib. nameOfConference


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  • Liu P, Pearce CM, Anastasiadi R-M et al. (2019). Covalently Crosslinked Nanogels: An NMR Study of the Effect of Monomer Reactivity on Composition and Structure. nameOfConference


  • Redivo L, Anastasiadi R-M, Pividori M et al. (2019). Prediction of self-assembly of adenosine analogues in solution: a computational approach validated by isothermal titration calorimetry.. nameOfConference


  • ZARBAKHSH A, RESMINI M, ZIELINSKA K et al. (2018). Interactions of NIPAM nanogels with model lipid multi-bilayers: A neutron reflectivity study. nameOfConference


  • Salinas Y, Hoerhager C, García-Fernández A et al. (2018). Biocompatible Phenylboronic-Acid-Capped ZnS Nanocrystals Designed As Caps in Mesoporous Silica Hybrid Materials for on-Demand pH-Triggered Release In Cancer Cells.. nameOfConference


  • Saito G, Velluto D, Resmini M (2018). Synthesis of 1,8-naphthalimide-based probes with fluorescent switch triggered by flufenamic acid. nameOfConference


  • Redivo L, Stredanský M, De Angelis E et al. (2018). Bare carbon electrodes as simple and efficient sensors for the quantification of caffeine in commercial beverages.. nameOfConference


  • Salinas Y, Castilla AM, Resmini M (2018). An l-proline based thermoresponsive and pH-switchable nanogel as a drug delivery vehicle. nameOfConference


  • ZARBAKHSH A, RESMINI M, HuiHui S (2018). Interaction of thermal responsive NIPAM nanogels with model lipid monolayers at the air-water interface. nameOfConference


  • Pellizzoni E, Tommasini M, Marangon E et al. (2017). Corrigendum to "Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma" [Biosens. Bioelectron. 86 (2016) 913-919].. nameOfConference


  • Zieli¿ska K, Campbell RA, Zarbakhsh A et al. (2017). Adsorption versus aggregation of NIPAM nanogels: new insight into their behaviour at the air/water interface as a function of concentration.. nameOfConference


  • Gutiérrez Ortiz AL, Berti F, Navarini L et al. (2017). Synthesis of p-coumaroylquinic acids and analysis of their interconversion. nameOfConference


  • Mirata F, Resmini M (2017). Metal Complexes and Imprinted Polymers for Shape-Selective Catalysis. nameOfConference


    QMRO: qmroHref
  • Papadimitriou SA, Robin MP, Ceric D et al. (2016). Fluorescent polymeric nanovehicles for neural stem cell modulation.. nameOfConference


  • Aksakal R, Resmini M, Becer CR (2016). SET-LRP of acrylates catalyzed by a 1 penny copper coin. nameOfConference


  • Aksakal R, Resmini M, Becer C (2016). Pentablock core-first star shaped polymers in less than 90 minutes via aqueous SET-LRP. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Pellizzoni E, Tommasini M, Marangon E et al. (2016). Fluorescent molecularly imprinted nanogels for the detection of anticancer drugs in human plasma. nameOfConference


  • Panagiotopoulou M, Salinas Y, Beyazit S et al. (2016). Molecularly Imprinted Polymer Coated Quantum Dots for Multiplexed Cell Targeting and Imaging.. nameOfConference


  • Panagiotopoulou M, Salinas Y, Beyazit S et al. (2016). Molecularly Imprinted Polymer Coated Quantum Dots for Multiplexed Cell Targeting and Imaging. nameOfConference


    QMRO: qmroHref
  • Papadimitriou SA, Salinas Y, Resmini M (2016). ChemInform Abstract: Smart Polymeric Nanoparticles as Emerging Tools for Imaging — The Parallel Evolution of Materials. nameOfConference


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  • Jorge AR, Chernobryva M, Rigby SEJ et al. (2016). Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity. nameOfConference


  • Papadimitriou SA, Salinas Y, Resmini M (2016). Smart Polymeric Nanoparticles as Emerging Tools for Imaging--The Parallel Evolution of Materials. nameOfConference


  • Zieli¿ska K, Sun H, Campbell RA et al. (2016). Smart nanogels at the air/water interface: Structural studies by neutron reflectivity. nameOfConference


  • Resmini M (2016). The 'Leaky Pipeline'. nameOfConference


    QMRO: qmroHref
  • Ray JV, Mirata F, Pérollier C et al. (2016). Smart coumarin-tagged imprinted polymers for the rapid detection of tamoxifen. nameOfConference


    QMRO: qmroHref
  • Aksakal R, Resmini M, Becer CR (2016). Pentablock star shaped polymers in less than 90 minutes via aqueous SET-LRP. nameOfConference


    QMRO: qmroHref
  • Mirata F, Resmini M (2015). Molecularly imprinted polymers for catalysis and synthesis. nameOfConference


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  • Ton X-A, Bui BTS, Resmini M et al. (2013). A Versatile Fiber-Optic Fluorescence Sensor Based on Molecularly Imprinted Microstructures Polymerized in Situ. nameOfConference


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  • Ton X, Bui BTS, Resmini M et al. (2013). A Versatile Fiber‐Optic Fluorescence Sensor Based on Molecularly Imprinted Microstructures Polymerized in Situ. nameOfConference


    QMRO: qmroHref
  • Cakir P, Cutivet A, Resmini M et al. (2013). Protein-size molecularly imprinted polymer nanogels as synthetic antibodies, by localized polymerization with multi-initiators.. nameOfConference


    QMRO: qmroHref
  • Servant A, Rogers S, Zarbakhsh A et al. (2013). Polymeric organic nanogels: structural studies and correlation between morphology and catalytic efficiency. nameOfConference


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  • Bonomi P, Servant A, Resmini M (2012). Modulation of imprinting efficiency in nanogels with catalytic activity in the Kemp elimination.. nameOfConference


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  • Resmini M (2012). Molecularly imprinted polymers as biomimetic catalysts.. nameOfConference


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  • Resmini M, Flavin K, Carboni D (2012). Microgels and nanogels with catalytic activity.. nameOfConference


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  • Hussain S, Khan A, Gul S et al. (2011). Identification of interactions involved in the generation of nucleophilic reactivity and of catalytic competence in the catalytic site Cys/His ion pair of papain.. nameOfConference


    QMRO: qmroHref
  • Servant A, Haupt K, Resmini M (2011). Tuning molecular recognition in water-soluble nanogels with enzyme-like activity for the kemp elimination.. nameOfConference


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  • Ostler EL, Resmini M, Boucher G et al. (2010). ChemInform Abstract: Polyclonal Antibody‐Catalyzed Hydrolysis of a β‐Lactam.. nameOfConference


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  • Maggiotti V, Resmini M, Gouverneur V (2010). ChemInform Abstract: Unprecedented Regiocontrol Using an Aldolase I Antibody.. nameOfConference


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  • Flavin K, Resmini M (2010). Molecular Imprinting with Nanomaterials. nameOfConference


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  • Flavin K, Resmini M (2010). ADVANCED NANOMATERIALS, 2 VOLUMES. nameOfConference

    DOI: doi

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  • Pasetto P, Flavin K, Resmini M (2009). Simple spectroscopic method for titration of binding sites in molecularly imprinted nanogels with hydrolase activity.. nameOfConference


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  • Jorge R, Watkinson M, Resmini M et al. (2009). CATL 63-Molecularly imprinted nanogels as phosphate hydrolysis promoters. nameOfConference

    DOI: doi

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  • Servant AMLI, Resmini M (2009). COLL 487-Catalytic imprinted nanogels for Kemp elimination: Synthesis and characterization. nameOfConference

    DOI: doi

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  • Flavin K, Resmini M (2009). Imprinted nanomaterials: a new class of synthetic receptors.. nameOfConference


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  • Carboni D, Flavin K, Servant A et al. (2008). The first example of molecularly imprinted nanogels with aldolase type I activity.. nameOfConference

    DOI: doi

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  • Gul S, Hussain S, Thomas MP et al. (2008). Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.. nameOfConference


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  • Carboni D, Flavin K, Servant A et al. (2008). The first example of molecularly imprinted nanogels with aldolase type I activity.. nameOfConference


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  • Boucher G, Said B, Ostler EL et al. (2007). Evidence that the mechanism of antibody-catalysed hydrolysis of arylcarbamates can be determined by the structure of the immunogen used to elicit the catalytic antibody.. nameOfConference


    QMRO: qmroHref
  • Pasetto P, Maddock SC, Resmini M (2005). Synthesis and characterisation of molecularly imprinted catalytic microgels for carbonate hydrolysis. nameOfConference


    QMRO: qmroHref
  • RESMINI M, Ostler EL, Brocklehurst K et al. (2005). Polyclonal catalytic antibodies. nameOfConference


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  • Sonkaria S, Boucher G, Flórez-Olvarez J et al. (2004). Evidence for 'lock and key' character in an anti-phosphonate hydrolytic antibody catalytic site augmented by non-reaction centre recognition: variation in substrate selectivity between an anti-phosphonate antibody, an anti-phosphate antibody and two hydrolytic enzymes.. nameOfConference


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  • Rodriguez AC, Ramos AP, Hawkes GE et al. (2004). Stereoselective synthesis of a novel pseudopeptide hapten for the generation of hydrolytic catalytic antibodies. nameOfConference


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  • Maggiotti V, Bahmanyar S, Reiter M et al. (2004). Unusual Reversal of Regioselectivity in Antibody‐Mediated Aldol Additions with Unsymmetrical Methyl Ketones.. nameOfConference


    QMRO: qmroHref
  • Maddock SC, Pasetto P, Resmini M (2004). Novel imprinted soluble microgels with hydrolytic catalytic activity. nameOfConference


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  • Reid JD, Hussain S, Bailey TSF et al. (2004). Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.. nameOfConference


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  • Maggiotti V, Bahmanyar S, Reiter M et al. (2004). Unusual reversal of regioselectivity in antibody-mediated aldol additions with unsymmetrical methyl ketones. nameOfConference


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  • Gul S, Sonkaria S, Pinitglang S et al. (2003). Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving-group determinant: evidence for the 'flexibility' hypothesis.. nameOfConference


    QMRO: qmroHref
  • Hussain S, Pinitglang S, Bailey TSF et al. (2003). Variation in the pH-dependent pre-steady-state and steady-state kinetic characteristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion.. nameOfConference


    QMRO: qmroHref
  • Ostler EL, Dean CJ, Barber N et al. (2002). A rat monoclonal antibody that catalyses the hydrolysis of a nitrophenyl-beta-lactam.. nameOfConference


    QMRO: qmroHref
  • Ostler EL, Resmini M, Brocklehurst K et al. (2002). Polyclonal catalytic antibodies.. nameOfConference


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  • Maggiotti V, Bahmanyar S, Houk KN et al. (2002). Theoretical studies on the antibody-catalyzed aldol reaction involving unsymmetrical enamine intermediates.. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Maggiotti V, Gouverneur V, Resmini M (2002). Unprecedented regiocontrol using an aldolase I antibody.. nameOfConference

    DOI: doi

    QMRO: qmroHref
  • Maggiotti V, Resmini M, Gouverneur V (2002). Unprecedented Regiocontrol Using An Aldolase I Antibody. nameOfConference


    QMRO: qmroHref
  • Maggiotti V, Resmini M, Gouverneur V (2002). Unprecedented regiocontrol using an aldolase I antibody.. nameOfConference


    QMRO: qmroHref
  • Ostler EL, Resmini M, Boucher G et al. (2002). Polyclonal antibody-catalysed hydrolysis of a beta-lactam.. nameOfConference


    QMRO: qmroHref
  • Florez-Alvarez J, Brocklehurst K, Gallacher G et al. (2002). Synthesis of an aminoalcohol hapten for the generation of catalytic antibodies. nameOfConference


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  • Krell T, Maclean J, Boam DJ et al. (2001). Biochemical and X-ray crystallographic studies on shikimate kinase: the important structural role of the P-loop lysine.. nameOfConference


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  • Brocklehurst K, Resmini M, Topham CM (2001). Kinetic and titration methods for determination of active site contents of enzyme and catalytic antibody preparations.. nameOfConference


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  • Brocklehurst K, RESMINI M, Gallacher G et al. (2001). Catalytic antibodies and their use in Prodrug activation. nameOfConference

    DOI: doi

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  • Topham CM, Gul S, Resmini M et al. (2000). The kinetic basis of a general method for the investigation of active site content of enzymes and catalytic antibodies: First-order behaviour under single-turnover and cycling conditions. nameOfConference


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  • Resmini M, Gul S, Carter S et al. (2000). A general kinetic approach to investigation of active-site availability in macromolecular catalysts. nameOfConference


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  • Benedetti F, Berti F, Flego M et al. (1998). A competitive immunoassay for the detection of esterolytic activity of antibodies and enzymes. nameOfConference


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  • Resmini M (1998). Determination of the catalytic site content of a polyclonal catalytic antibody preparation. nameOfConference


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  • Resmini M, Vigna R, Simms C et al. (1997). Characterization of the hydrolytic activity of a polyclonal catalytic antibody preparation by pH-dependence and chemical modification studies: Evidence for the involvement of Tyr and Arg side chains as hydrogen-bond donors. nameOfConference


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  • Annunziata R, Ferrari M, Papeo G et al. (1997). Asymmetric synthesis of 4(R)tert-butyl-8a(S)hydroxycarbonyl-4,6,7,8,8a,9-hexahydro-1-alkylpyrr olo[3,2-f]indolizines via intramolecular iminium ion cyclization. nameOfConference


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  • Busch MHA, Boelens HFM, Kraak JC et al. (1996). Critical evaluation of the applicability of capillary zone electrophoresis for the study of hapten-antibody complex formation. nameOfConference


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  • Resmini M, Meekel AAP, Pandit UK (1996). Catalytic antibodies: Regio- and enantioselectivity in a hetero Diels-Alder reaction. nameOfConference


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  • Meekel AAP, Resmini M, Pandit UK (1996). Regioselectivity and enantioselectivity in an antibody catalyzed hetero Diels-Alder reaction. nameOfConference


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  • Meekel AAP, Resmini M, Pandit UK (1995). First example of an antibody-catalysed hetero-Diels-Alder reaction. nameOfConference


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  • Ferrari M, Orsini F, Resmini M et al. (1994). The unusual reactivity of 9-oxa-4-thia-tetracyclo[5.5.1.02,7.010,13] tridecan-12-one-3-spiro-1 '-cyclopentan-3'-ones: a molecular modelling study. nameOfConference


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  • Jommi G, Orsini F, Resmini M et al. (1991). A stereoconvergent approach to dicyclopenta[a,d]cyclooctane terpenoids via a very mild cope reaction. nameOfConference


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Supervision

Current PhD opportunity

  • Self-assembled block copolymers as drug delivery systems for skin treatments

PhD supervision

  • Roberta Bilardo
  • Pauline de Bigault de Cazanove
  • Federico Traldi
  • Alena Vdovchenko