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School of Biological and Behavioural Sciences

About the facility

Transmission Electron Microscope (TEM) Facility

The Transmission Electon Microscopy (TEM) facility, at the School of Biological and Behavioural Sciences, offers comprehensive imaging support for a diverse range of biological specimens. Our room temperature TEM facility specializes in ultrastructure visualization and is equipped with Ultracut E Ultramicrotome and freeze fracture  to aid in sample preparation.​

In addition, our cryo-EM facility is specialized in single particle analysis and provides high-quality imaging of extracellular vesicles such as exosomes. We work closely with researchers from across the University, as well as external users from academia and industry, to produce high-resolution structures of macromolecular complexes including membrane proteins and protein complexes.​

Whether you need imaging support for small macromolecular complexes or larger organisms, our facilities are accessible to all researchers. Please feel free to contact us for more information on how our facility can support your research needs.

We provide a wide range of services to support internal, external researchers and industry including sample preparation and imaging as well as support the development of a full project.

Here is a brief list of the service provided:

  • Cryo-grid optimization and screening for data collection.
  • Single particle data collection and data processing.
  • Ultrastructure analysis of tissue or cells in suspension (resin embedded sample).
  • Freeze fracture and freeze etching.
  • Imaging service:
  • Negative stained samples (ECV, nanogel, nanoparticles and biological sample suspension).
  • Frozen hydrated biological sample in suspension.
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