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School of Physical and Chemical Sciences

Dr Peter Wyatt

Peter

Senior Lecturer

Email: p.b.wyatt@qmul.ac.uk
Telephone: +44 (0)20 7882 3267
Room Number: Room 1.10, Joseph Priestley building

Undergraduate Teaching

  • Essential Skills for Chemists (Tutorials) (CHE100)
  • Practical Chemistry (CHE211)
  • Organic Synthesis (CHE302U)
  • Bioorganic Chemistry (CHE307)
  • Advanced Analytical Chemistry and Spectroscopy (CHE308U)
  • Advanced Practical Chemistry 2 (CHE311)
  • Drug Design and Development (CHE406U)
  • Chemistry/Pharmacetucial Chemistry MSci Research Project (CHE751)

Research

Research Interests:

Peter Wyatt has over 20 years experience of research in organic synthesis, including the chemical synthesis of analogues of biologically important molecules, especially unusual amino acids, plant polyphenols, carbohydrates and phosphonic acid derivatives.

Current areas of work are as follows:

  • Structure-activity studies of synthetic polyphenols designed to protect against heart disease
  • Preparation of light emitting lanthanide complexes based on fluorine-containing organic ligands
  • Reaction of aspartic and glutamic acid derivatives with organometallic nucleophiles
  • Preparation and reactivity of alkynyl C-glycosides
  • Stereoselective addition reactions of unsaturated phosphonates.

Find out more on Peter Wyatt's website

Research department

  • Chemistry

Publications

    • Liu J, Du J, Phillips AE et al. (2022), Neutron powder diffraction study of the phase transitions in deuterated methylammonium lead iodide $nameOfConference


    • Lyu C, Li H, Zhou S et al. (2021), Bright and Efficient Sensitized Near-Infrared Photoluminescence from an Organic Neodymium-Containing Composite Material System. $nameOfConference


    • Ye H, Gorbaciova J, Lyu C et al. (2021), Manipulation of Molecular Vibrations on Condensing Er3+State Densities for 1.5 μm Application $nameOfConference


    • Adekenova KS, Wyatt PB, Adekenov SM (2021), The preparation and properties of 1,1-difluorocyclopropane derivatives $nameOfConference


    • Li H, Liu X, Lyu C et al. (2021), Erratum: Enhanced 1.54 μm luminescence of a perfluorinated erbium complex sensitized by perfluorinated Pt(ii) and Zn(ii) phthalocyanines with 980 nm emission (J. Mater. Chem. C (2021) DOI: 10.1039/d0tc05301e) $nameOfConference


    • Li H, Liu X, Lyu C et al. (2020), Enhanced 1.54 µm luminescence of perfluorinated erbium complex sensitized by perfluorinated Pt(II) and Zn(II) phthalocyanines with 980 nm emission $nameOfConference


    • Lyu C, Li H, Wyatt PB et al. (2020), Prolonged and efficient near-infrared photoluminescence of a sensitized organic ytterbium-containing molecular composite $nameOfConference


    • Patel H, Mothia B, Patel J et al. (2020), Cytotoxicity of some synthetic bis(arylidene) derivatives of cyclic ketones towards cisplatin-resistant human ovarian carcinoma cells $nameOfConference


    • Li HF, Liu XQ, Lyu C et al. (2020), Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer $nameOfConference


    • Li H-F, Liu X-Q, Lyu C et al. (2020), Enhanced 1.54-μm photo- and electroluminescence based on a perfluorinated Er(III) complex utilizing an iridium(III) complex as a sensitizer. $nameOfConference


    • HU J, KARAMSHUK S, GORBACIOVA J et al. (2018), Enhancing the sensitization efficiency of erbium doped organic complexes by heavy halogen substitution $nameOfConference


    • Hu J, Wyatt PB, Gillin WP et al. (2018), Continuous Tuning of Organic Phosphorescence by Diluting Triplet Diffusion at the Molecular Level. $nameOfConference


    • HU J, KARAMSHUK S, GORBACIOVA J et al. (2018), High sensitization efficiency and energy transfer routes for population inversion at low pump intensity in Er organic complexes for IR amplification $nameOfConference


    • Lu H, Peng Y, Ye HQ et al. (2017), Sensitization, energy transfer and infra-red emission decay modulation in Yb3+-doped NaYF4 nanoparticles with visible light through a perfluoroanthraquinone chromophore $nameOfConference


    • WYATT PB, Metcalf JS, Lobner D et al. (publicationYear), Analysis of BMAA enantiomers in cycads, cyanobacteria, and mammals: in vivo formation and toxicity of D-BMAA $nameOfConference


    • GILLIN WP, wyatt PB, Hernandez I et al. (2016), Functionalisation of ligands through click chemistry: long-lived NIR emission from organic Er(III) complexes with a perfluorinated core and a hydrogen-containing shell $nameOfConference


    • Utley JHP, Folmer Nielsen M, WYATT PB (2015), Electrogenerated Bases and Nucleophiles $nameOfConference


    • Coutinho JT, Pereira LCJ, Martín-Ramos P et al. (2015), Field-induced single-ion magnetic behaviour in a highly luminescent Er3+ complex $nameOfConference


    • WYATT PB (2015), 5.2.16.11 Tin cyanides and Fulminates 5.2.17.9 Acylstannanes (Including S, Se and Te Analogues) 5.2.18.8 Imidoylstannanes, Diazoalkylstannanes, Tin Isocyanates and Tin Isothiocyanates $nameOfConference

    • Coutinho JT, Pereira LCJ, Martín-Ramos P et al. (2014), Field-induced single-ion magnetic behaviour in a highly luminescent Er3+ complex $nameOfConference


    • Van Staalduinen LM, McSorley FR, Schiessl K et al. (2014), Erratum: Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, (5171-5176) DOI: 10.1073/pnas.1320039111) $nameOfConference


    • Peng Y, Ye H, Li Z et al. (2014), Visible-range Sensitization of Er3+-based Infrared Emission from Perfluorinated 2-Acylphenoxide Complexes (American Chemical Society Live Slides presentation) $nameOfConference

    • Peng Y, Ye H, Li Z et al. (2014), Visible-Range Sensitization of Er3+-Based Infrared Emission from Perfluorinated 2-Acylphenoxide Complexes $nameOfConference


    • van Staalduinen LM, McSorley FR, Schiessl K et al. (2014), Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates $nameOfConference


    • Ye HQ, Li Z, Peng Y et al. (2014), Organo-erbium systems for optical amplification at telecommunications wavelengths $nameOfConference


    • Ye H, Peng Y, Li Z et al. (2013), Effect of Fluorination on the Radiative Properties of Er3+ Organic Complexes: An Opto-Structural Correlation Study $nameOfConference


    • Li Z, Dellali A, Malik J et al. (2013), Luminescent Zinc(II) Complexes of Fluorinated Benzothiazol-2-yl Substituted Phenoxide and Enolate Ligands. $nameOfConference


    • Hernández I, Zheng Y-X, Motevalli M et al. (2013), Efficient sensitized emission in Yb(III) pentachlorotropolonate complexes $nameOfConference


    • McSorley FR, Wyatt PB, Martinez A et al. (2012), PhnY and PhnZ Comprise a New Oxidative Pathway for Enzymatic Cleavage of a Carbon-Phosphorus Bond $nameOfConference


    • Khademi S, Song JY, Wyatt PB et al. (2012), Ambipolar charge transport in "traditional" organic hole transport layers. $nameOfConference


    • Rolfe NJ, Heeney M, Wyatt PB et al. (2011), The effect of deuteration on organic magnetoresistance $nameOfConference


    • Hernández I, Pathumakanthar N, Wyatt PB et al. (2010), Cooperative infrared to visible up conversion in Tb3+, Eu3+, And Yb3+ containing polymers. $nameOfConference


    • Wright HM, Wyatt PB, Viles JH (2010), Is oxidation the trigger of the Amyloid Cascade?: A synthesis of 2-oxo-histidine for incorporation into the Amyloid beta sequence. $nameOfConference

    • HUSSAIN A, WYATT PB (2010), ChemInform Abstract: 2‐(Penta‐1,3‐dienyl)oxazolidines: Synthesis of Hydroxylated Piperidines by a Stereoselective Diels‐Alder Reaction. $nameOfConference


    • MALIK S, WYATT PB (2010), ChemInform Abstract: Preparation of (RS)‐5‐Amino‐3‐carboxypentanoic Acid. $nameOfConference


    • HUSSAIN A, MOTEVALLI M, UTLEY JHP et al. (2010), ChemInform Abstract: The Anodic Oxidation of cis‐1,2,3,4‐Tetrahydronaphthalene‐2,3‐ dicarboxylic Acid and Its Derivatives: Competition Between Oxidative Bisdecarboxylation and Dilactone Formation. $nameOfConference


    • ROBINSON AJ, WYATT PB (2010), ChemInform Abstract: Addition of a Reformatsky Reagent to N‐Anthracene‐9‐sulfonyl and Related Imines: Synthesis of Protected β‐Amino Acids. $nameOfConference


    • ABRAHAMS I, MOTEVALLI M, ROBINSON AJ et al. (2010), ChemInform Abstract: Addition to Activated Imines of Enolates from Chiral N‐ Acyloxazolidinones. $nameOfConference


    • ERU E, HAWKES GE, UTLEY JHP et al. (2010), ChemInform Abstract: Electro‐Organic Reactions. Part 41. Diels‐Alder Reactions of o‐ Quinodimethanes from the Cathodic Reduction of α,α′‐ Dibromo‐1,2‐dialkylbenzenes. $nameOfConference


    • ARVANITIS E, MOTEVALLI M, WYATT PB (2010), ChemInform Abstract: Enantioselective Synthesis of (S)‐2‐(Aminomethyl)butanedioic Acid Using Chiral β‐Alanine α‐Enolate Equivalents. $nameOfConference


    • AZAM S, D'SOUZA AA, WYATT PB (2010), ChemInform Abstract: Enantioselective Synthesis of 2‐Substituted 4‐Aminobutanoic Acid (GABA) Analogues via Cyanomethylation of Chiral Enolates. $nameOfConference


    • ARVANITIS E, ERNST H, LUDWIG AA et al. (2010), ChemInform Abstract: Enantioselective Synthesis of 2‐Substituted 3‐Aminopropanoic Acid (β‐Alanine) Derivatives Which are β‐Analogues of Aromatic Amino Acids. $nameOfConference


    • Utley JHP, Nielsen MF, Janssen RG et al. (2010), ChemInform Abstract: Electroorganic Reactions. Part 48. Pathways for Carbon—Carbon Bond Formation: The Redox Chemistry of Quinodimethanes and of Alkenyl‐Substituted Heteroaromatics $nameOfConference


    • Wyatt PB, Villalonga‐Barber C, Motevalli M (2010), ChemInform Abstract: Synthesis and Diels—Alder Reactivity of Chiral 2‐(Alk‐1‐enyl)‐1,3,2‐diazaphospholidine 2‐Oxides. $nameOfConference


    • Wyatt PB, Blakskjaer P (2010), ChemInform Abstract: An Enantioselective Synthesis of (R)‐2‐Amino‐1‐hydroxyethylphosphonic Acid (III) by Hydrolytic Kinetic Resolution of (.+‐.)‐Diethyl Oxiranephosphonate. $nameOfConference


    • Hernandez I, Tan RHC, Wyatt PB et al. (2010), High-pressure study of non-radiative de-excitation mechanisms in perfluorinated organic erbium(III) phosphinates $nameOfConference


    • Rolfe NJ, Heeney M, Wyatt PB et al. (2009), Elucidating the role of hyperfine interactions on organic magnetoresistance using deuterated aluminium tris(8-hydroxyquinoline) $nameOfConference


    • Zheng Y, Pearson J, Tan RHC et al. (2009), Erbium bis(pentafluorophenyl)phosphinate: a new hybrid material with unusually long-lived infrared luminescence (vol 20, pg S430, 2009) $nameOfConference


    • Rolfe NJ, Heeney M, Wyatt PB et al. (2009), Elucidating the role of hyperfine interactions on organic magnetoresistance using deuterated aluminium tris(8-hydroxyquinoline) $nameOfConference

    • Hernández I, Tan RHC, Pearson JM et al. (2009), Nonradiative de-excitation mechanisms in long-lived erbium(III) organic compounds ErxY1-x[(p-CF3-C6F4)2PO2]3. $nameOfConference


    • Zheng Y, Pearson J, Tan RHC et al. (2009), Erbium bis(pentafluorophenyl) phosphinate: a new hybrid material with unusually long-lived infrared luminescence $nameOfConference


    • Liu FT, Agrawal SG, Movasaghi Z et al. (2008), Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib $nameOfConference


    • Zheng YX, Motevalli M, Tan RHC et al. (2008), Near IR luminescent rare earth 3,4,5,6-tetrafluoro-2-nitrophenoxide complexes: Synthesis, X-ray crystallography and spectroscopy $nameOfConference


    • WYATT PB (2008), (Tributylphosphoranylidene)acetonitrile $nameOfConference


    • Tan RHC, Pearson JM, Zheng Y et al. (2008), Evidence for erbium-erbium energy migration in erbium(III) bis(perfluoro-p-tolyl)phosphinate $nameOfConference


    • Shamash J, Powles T, Ansell W et al. (2007), Erratum: GAMEC - A new intensive protocol for untreated poor prognosis and relapsed or refractory germ cell tumours (British Journal of Cancer (2007) 97, (308-314) DOI: 10.1038/6603865) $nameOfConference


    • Shamash J, Powles T, Ansell W et al. (2007), GAMEC - a new intensive protocol for untreated poor prognosis and relapsed or refractory germ cell tumours $nameOfConference


    • Cheng EWC, Mandalia RT, Motevalli M et al. (2006), Stereoselective Diels-Alder reactions of 3-phosphonopropenoyl derivatives of 1,3-oxazolidin-2-ones $nameOfConference


    • Tan RHC, Motevalli M, Abrahams I et al. (2006), Quenching of IR luminescence of erbium, neodymium, and ytterbium beta-diketonate complexes by ligand C-H and C-D bonds. $nameOfConference


    • Wyatt P, Abrahams I, GILLIN WP et al. (2006), Quenching of IR Luminescence of Erbium, Neodymium, and Ytterbium alpha-Diketonate Complexes by Ligand C-H and C-D Bonds $nameOfConference


    • Coumbarides GS, Motevalli M, Muse WA et al. (2006), Stereoselective synthesis of (E)-mannosylidene derivatives using the Wittig reaction $nameOfConference


    • Winkless L, Tan RHC, Zheng Y et al. (2006), Quenching of Er(III) luminescence by ligand C-H vibrations: Implications for the use of erbium complexes in telecommunications $nameOfConference


    • WYATT PB (2006), Science of Synthesis, Volume 15: Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom Edited by David Black $nameOfConference

    • Mateo Alonso A, Horcajada R, Groombridge HJ et al. (2005), Synthesis of phenazine derivatives for use as precursors to electrochemically generated bases. $nameOfConference


    • Alonso AM, Horcajada R, Motevalli M et al. (2005), The reactivity, as electrogenerated bases, of chiral and achiral phenazine radical-anions, including application in asymmetric deprotonation. $nameOfConference


    • Chan KL, Coumbarides GS, Islam S et al. (2005), Synthesis of propargyl C-glycosides using allenyltributylstannane $nameOfConference


    • Alonso AM, Horcajada R, Groombridge HJ et al. (2004), Generation of Strong, Homochiral Bases by Electrochemical Reduction of Phenazine Derivatives. $nameOfConference


    • Alonso AM, Horcajada R, Groombridge HJ et al. (2004), Generation of strong, homochiral bases by electrochemical reduction of phenazine derivatives. $nameOfConference


    • Wyatt PB (2004), Imidoylstannanes, Diazoalkylstannanes, Tin Isocyanates, and Tin Isothiocyanates $nameOfConference


    • Wyatt PB (2004), Tin Cyanides and Fulminates $nameOfConference


    • Wyatt PB (2004), Acylstannanes (Including S, Se, and Te Analogues) $nameOfConference


    • Gascon-Lopez M, Motevalli M, Paloumbis G et al. (2003), C-Glycosylidene derivatives (exo-glycals): their synthesis by reaction of protected sugar lactones with tributylphosphonium ylids, conformational analysis and stereoselective reduction $nameOfConference


    • Utley JHP, Groombridge H, Horcajada R et al. (2003), Electro-organic reactions. Part 59. Chiral and achiral phenazine radical-anions as electrogenerated bases 203rd Electrochemical Society Meeting

    • Kumar A, Ghilagaber S, Knight J et al. (2002), The homologation of histidine $nameOfConference


    • WYATT PB (2002), Organic Electrochemistry (4th Edition),: Edited by H. Lund and O. Hammerich, Marcel Decker, 2001, 1393 pp. ISBN 0-8247-0430-4 $nameOfConference


    • WYATT PB (2002), Product Subclass 16: Tin Cyanides and Fulminates $nameOfConference

    • WYATT PB (2002), Product Subclass 17: Acylstannanes (Including S, Se, and Te Analogues) $nameOfConference

    • WYATT PB (2002), Product Subclass 18: Imidoylstannanes, Diazoalkylstannanes, Tin Isocyanates, and Tin Isothiocyanates $nameOfConference

    • Gardner S, Motevalli M, Shastri K et al. (2002), Synthetic and structural chemistry of enantiomerically pure 1-phenyl-2-carboxyethylphosphonic acid and its derivatives $nameOfConference


    • Wyatt* PB (2001), Book Review, Modern Animation Methods $nameOfConference


    • WYATT PB (2001), Modern Amination Methods, Ed A. Ricci $nameOfConference

    • Utley JHP, Oguntoye E, Smith CZ et al. (2000), Electro-organic reactions. Part 52: Diels-Alder reactions in aqueous solution via electrogenerated quinodimethanes $nameOfConference


    • Wyatt PB, Blakskjær P (1999), An enantioselective synthesis of (R)-2-amino-1-hydroxyethylphosphonic acid by hydrolytic kinetic resolution of (±)-diethyl oxiranephosphonate $nameOfConference


    • Wyatt PB, Villalonga-Barber C, Motevalli M (1999), Synthesis and Diels-Alder reactivity of chiral 2-(alk-1-enyl)-1,3,2 diazaphospholidine 2-oxides $nameOfConference


    • Arvanitis E, Ernst H, Ludwig AA et al. (1998), Enantioselective synthesis of 2-substituted 3-aminopropanoic acid (β-alanine) derivatives which are β-analogues of aromatic amino acids $nameOfConference


    • Utley JHP, Nielsen MF, Janssen RG et al. (1998), Electro-Organic Reactions. Part 48: Pathways for Carbon-Carbon Bond Formation: The Redox Chemistry of Quinodimethanes and of Alkenyl-Substituted Heteroaromatics $nameOfConference


    • Arvanitis E, Motevalli M, Wyatt PB (1996), Enantioselective synthesis of (S)-2-(aminomethyl)butanedioic acid using chiral β-alanine α-enolate equivalents $nameOfConference


    • Oguntoye E, Szunerits S, Utley JHP et al. (1996), Electro-organic reactions. Part 46. Diels-Alder trapping of o-quinodimethane generated by redox-mediated cathodic reduction of α,α′-dibromo-o-xylene in the presence of hindered dienophiles $nameOfConference


    • Azam S, D'Souza AA, Wyatt PB (1996), Enantioselective synthesis of 2-substituted 4-aminobutanoic acid (GABA) analogues via cyanomethylation of chiral enolates $nameOfConference


    • Eru E, Hawkes GE, Utley JHP et al. (1995), Electro-organic reactions. Part 41. Diels-Alder reactions of o-quinodimethanes from the cathodic reduction of α, α′-dibromo-1,2-dialkylbenzenes $nameOfConference


    • D'Souza AA, Motevalli M, Robinson AJ et al. (1995), ( R )-(+)-3-Amino-2-phenylpropanoic acid: a revised absolute configuration based on an enantioselective synthesis and an X-ray crystal structure of the salt with (1 S )-(+)-camphor-10-sulfonic acid $nameOfConference


    • Abrahams I, Motevalli M, J. Robinson A et al. (1994), Addition to activated imines of enolates from chiral N-acyloxazolidinones $nameOfConference


    • Motevalli M, O'Brien P, Robinson AJ et al. (1993), The preparation, reactivity, and crystal structure of a 1 : 1 adduct of dimethylzinc and (-)-sparteine $nameOfConference


    • Malik S, Wyatt PB (1993), Preparation of (rs)-5-amino-3-carboxypentanoic acid (1) $nameOfConference


    • Hussain A, Wyatt PB (1993), 2-(penta-1,3-dienyl)oxazolidines: synthesis of hydroxylated piperidines by a stereoselective diels-alder Reaction $nameOfConference


    • Robinson AJ, Wyatt PB (1993), Addition of a Reformatsky reagent to N-anthracene-9-sulfonyl and related imines: Synthesis of protected β-amino acids $nameOfConference


    • Hussain A, Motevalli M, Utley JHP et al. (1993), The Anodic Oxidation of cis-1,2,3,4-Tetrahydronaphthalene-2,3-dicarboxylic Acid and Its Derivatives: Competition between Oxidative Bisdecarboxylation and Dilactone Formation $nameOfConference


    • O'Brien P, Wang G, Wyatt PB (1992), Studies of the kinetics of the reduction of chromate by glutathione and related thiols $nameOfConference


    • JONES JH, RATHBONE DL, WYATT PB (1988), ChemInform Abstract: The Regiospecific Alkylation of Histidine Side Chains. $nameOfConference


    • ACHESON RM, BIRTWISTLE DH, CONSTABLE EC et al. (1987), ChemInform Abstract: The Synthesis of Some Sterically Hindered Acridines and a High‐Pressure Methylation. $nameOfConference


    • ACHESON RM, BIRTWISTLE DH, WYATT PB (1987), ChemInform Abstract: The Synthesis of Some 10‐Phenylacridinium Salts and Related Compounds. $nameOfConference


    • Jones* J, Rathbone D, Wyatt P (1987), The Regiospecific Alkylation of Histidine Side Chains $nameOfConference


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