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Pragmatic Clinical Trials Unit

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Trials

Study Acronym Eye-2-i                                                               

Study Title                                                                                    

 The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness & cost effectiveness of a team-based motivational engagement intervention to improve engagement                                                                   
PCTU Ref             P252                              
Chief Investigator 

Dr Kathy Greenwood, University of Sussex
Funder/Funding Stream  NIHR Health Services & Delivery Research                                                                                                                     

 

Study Acronym  FLO-ELA                                                         
Study Title                           

FLuid Optimisation in Emergency LAparotomy. Open, multi-centre,
randomised controlled trial of cardiac output -guided haemodynamic therapy compared
to usual care in patients undergoing emergency bowel surgery                                              
PCTU Ref P217
Chief Investigator 

Dr Mark Edwards, University Hospital Southampton NHS Foundation Trust
Funder/Funding Stream     NIHR Health Technology Assessment                                                                                                                                      

 

Study Acronym HABSelect                                                              

Study Title                                              

 Selection of sperm for Intracytoplasmic Sperm Injection (ICSI) by prior hyaluronic acid binding: improving the outcomes of Assisted Conception procedures and reducing miscarriage rates. 
PCTU Ref             P095                             
Chief Investigator 

Dr David Miller, University of Leeds
Funder/Funding Stream  NIHR Efficacy and Mechanism Evaluation                                                                                                                

  

Study Acronym PIMS                                                             

Study Title                                                                           

 A multicentre interventional comparative randomised controlled clinical trial comparing face-down positioning, with an inactive face-forward position on the outcome of surgery for large macular holesPositioning in Macular hole Surgery (Positioning in Macular hole Surgery)
PCTU Ref             P110                              
Chief Investigator 

Professor James Bainbridge, University College London
Funder/Funding Stream  NIHR Research for Patient Benefit                                                                                                                   

Programmes 

Study Acronym EMPOWER                                                               
Study Title EMPOWER: Enabling and Motivating People (with a Personality Disorder) in Occupation, Wellbeing, Education and Responsibility
                                                                                
PCTU Ref P257
Chief Investigator 

Dr Janet Feigenbaum, North East London NHS Foundation Trust
Funder/Funding Stream      NIHR Programme Grant for Applied Research

 

Study Acronym ENRICH                                                              
Study Title                                                             Enhanced discharge from inpatient to community mental health care (ENRICH): a programme of applied research to manualise, pilot and trial a Peer Worker intervention                                                                                
PCTU Ref P154
Chief Investigator 

Dr Steve Gillard, St George's, University of London
Funder/Funding Stream      NIHR Programme Grant for Applied Research

 

Study Acronym         IMP2ART                                                        
Study Title                                                

Implementing supported asthma self-management in routine clinical care:  designing, refining, piloting and evaluating clinical and cost-effectiveness of a whole systems implementation strategy
PCTU Ref P243
Chief Investigator 

Dr Hilary Pinnock, University of Edinburgh
Funder/Funding Stream      NIHR Programme Grant for Applied Research

 

Study Acronym NEON                                                         
Study Title                                           Personal experience as a recovery resource in severe mental illness: Narrative Experiences ONline (NEON) Programme                                                                         
PCTU Ref P227
Chief Investigator 

Professor Mike Slade, University of Nottingham
Funder/Funding Stream      NIHR Programme Grant for Applied Research

 

Study Acronym REACH                                                           
Study Title                                  The REACH Pregnancy Programme (Research for Equitable Antenatal Care and Health)                                                                                  
PCTU Ref P123
Chief Investigator 

Professor Angela Harden, University of East London
Funder/Funding Stream      NIHR Programme Grant for Applied Research

Other

Study Acronym SWATS                                                            
Study Title     Routinely embedding recruitment and retention interventions within randomised controlled trials                                                                            
PCTU Ref P268
Chief Investigator 

Professor David Torgerson, University of York
Funder/Funding Stream      MRC Methodology Research Panel
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