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Ms Elisabetta Sciacca, B.Sc, MSc

Elisabetta

Visiting PhD Student

Centre: Centre for Translational Bioinformatics

Email: e.sciacca@qmul.ac.uk
Telephone: +44 (0) 2078 822 105

Profile

Elisabetta Sciacca, PhD Visiting Researcher.

PhD Student in Complex systems for Physical, Socio-Economic and Life Science.

Department of Clinical and Experimental Medicine, Bioinformatics Unit

University of Catania

Academic Background

  • Lipari School on computational complex and social systems
  • Ph.D Student: Complex systems for Physical, Socio-Economic and Life Science, University of Catania - Italy
  • Master Degree in Telecommunication Engineering: University of Catania - Italy;
  • Bachelor in Electronic Engineering: University of Catania - Italy

Professional Experience

Operation engineer
Operation and maintenance activities on several physical, virtual and cloud servers for a Vodafone Global messaging platform.

Software developer
ABAP Software optimization. Consultant for ST Microelectrionics.

 

Research

Research Interests:

Differentially Expressed Genes in synovial biopsies of Rheumatoid Arthritis patients are analysed by MITHrIL (Mirna enriched paTHway Impact anaLysis) for the analysis of signaling pathways. The method takes as input the expression values of genes and/or microRNAs and returns a list of pathways sorted according to their degree of deregulation.

The evaluation of the gene perturbation profile of early RA patients pre-DMARD against post-DMARD will permit to determine if any significant difference can be observed at this stage (responders Vs non-responders).

Basing on the above, a Machine learning model on early RA samples can be built to evaluate drug sensitivity (with respect to DMARD or Biologicals treatments).

Project Title

Analysis of gene perturbation profiles performed with a pathway-aware algorithm for pathotype classification of RA patients.

Supervisors

Dr Lewis Myles

Professor Costantino Pitzalis

 

Publications

Galluccio, L., Grasso, C., Milardo, S., Schembra, G., & Sciacca, E. (2018, November). An Experimental Testbed for Managing BAN Services at the Network Edge. In 2018 14th International Conference on Network and Service Management (CNSM) (pp. 333-337). IEEE.

Galluccio, L., Milardo, S., & Sciacca, E. (2017, May). A feasibility analysis on the use of ultrasonic multihop communications for e-health applications. In 2017 IEEE International Conference on Communications (ICC) (pp. 1-6). IEEE.

Galluccio, L., Milardo, S., & Sciacca, E. (2017, May). Demo abstract an ultrasonic intra body area network for ehealth applications. In 2017 IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS) (pp. 982-983). IEEE.

Bellomo, F., Beritelli, F., & Sciacca, E. (2014, October). Robustness of forensic speaker verification systems based on Alize/Lia_Ral toolkit. In 2014 IEEE Workshop on Biometric Measurements and Systems for Security and Medical Applications (BIOMS) Proceedings (pp. 92-97). IEEE.

(Under Submission) Sciacca, E., Galluccio, L. (2019, April). Impulse Response Analysis of Ultrasonic Human-Mimicking Channel

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