Lou Metherell is a Professor of Endocrine Genetics.
She obtained a BSc in Biology from the University of Manchester in 1985 followed by a postgraduate diploma in Human Genetics at the University of Aberdeen in 1989. After a brief period in industry she returned to science and was awarded her PhD from the University of Greenwich in 1999. She joined the Centre for Endocrinology at WHRI in 1998, where her research has focused on the genetics of endocrine disease, particularly disorders of adrenal insufficiency.
l.a.metherell@qmul.ac.uk
Li Chan is a Reader in Molecular Endocrinology and Metabolism/Honorary Consultant in Paediatric Endocrinology
Dr Chan completed her PhD at QMUL/Barts Health studying the melanocortin accessory proteins and its involvement in adrenal function and metabolism. Her specialist clinical interest is in the investigation and management of paedaitric adrenal disorders and childhood obesity. She has worked on MRAPs and Familial Glucocorticoid Deficiency over the last 15 years, working closely with Professor Lou Metherell on establishing molecular mechanisms, models and phenotype-genotype correlations in the condition.
l.chan@qmul.ac.uk
Rathi Prasad is a Consultant in Paediatric Endocrinology and Honorary Clinical Senior Lecturer at Barts Health/ QMUL.
Her clinical practice incorporates all areas of Paediatric Endocrinology, with particular interest in adrenal disorders and differences in sex development. She was awarded her PhD on the role of oxidative stress in the pathogenesis of Triple A syndrome and familial glucocorticoid deficiency, from QMUL in 2014. Her current research is focused on deciphering mechanisms of disease related to sphingosine-1-phosphate lyase (SGPL1) deficiency, a multi-systemic disorder of sphingolipid metabolism incorporating adrenal disease, nephrotic syndrome and wider endocrinopathy.
rathi.prasad@nhs.net
Helen Storr is a Professor and Honorary Consultant in Paediatric Endocrinology.
Dr Storr’s clinical paediatric endocrine practice is broad with key clinical interests including paediatric Cushing’s syndrome, disorders of growth and adrenal disorders. She leads an active programme of clinical and laboratory research which focuses on the molecular basis of Triple A syndrome and childhood growth disorders.
h.l.storr@qmul.ac.uk
Chris Smith is a Post Doctoral Researcher.
He completed his PhD at QMUL researching the differential wound healing found in human gums and skin. His research now focuses on SGPL1, a mutation in which causes PAI and can also manifest as ichthyosis, a disorder of skin keratinisation.
c.j.smith@qmul.ac.uk
Avinaash Maharaj is a clinical Post Doctoral Researcher.
Avi has a background in acute medicine but his PhD involved elucidating novel genetic causes of primary adrenal insufficiency and investigating the effects of Sphingosine 1-phosphate lyase deficiency on adrenal steroidogenesis. His current research focuses on the GH/IGF-1 axis and underlying genetic basis of short stature syndromes.
a.v.maharaj@qmul.ac.uk
Charlotte Hall is a Study Coordinator and Research Analyst.
She completed her PhD at UCL identifying and characterising novel genes and disease mechanisms in Arrhythmogenic cardiomyopathy focusing on Filamin C. Her research now focuses on adrenal diseases completing genotype/phenotype clinical databases, analysing RNA sequencing data and coordinating clinical studies.
charlotte.hall@qmul.ac.uk
Jack Williams is a Post-Doctoral Researcher.
He undertook his PhD at the University of Manchester studying the role of circadian rhythms in breast cancer with Professors Charles Streuli and Qing-Jun Meng. He now works with Professor Metherell investigating how mutations in NNT and SGPL1 cause adrenal insufficiency.
jack.williams@qmul.ac.uk