You will learn and undertake a research project in the multi-million-pound, state of the art Blizard Building, and benefit from access to facilities such as the biofabrication lab and collaborative research centres.
The building was designed by leading architect Will Alsop in partnership with Amec with its 9,000m2 providing world-class teaching and research facilities including open-plan laboratories, office space and the 400-seat Perrin Lecture Theatre. The Blizard houses many state of the art facilities, including light microscopy, flow cytometry, high-content screening and biological services. The wider medical school adds to this with facilities such as genomic and proteomic analysis, histopathology and statistical analysis.
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The CRoss-InstitutE Advanced Tissue Engineering (CREATE) Lab is a new core facility housed at the Blizard Institute managed by Regenerative Medicine Programme Co-Director Dr John Connelly, which is dedicated to biofabrication of advanced 3D tissues and microfluidic devices. The cross-faculty initiative houses state-of-the-art equipment for 3D bio-printing, microfabrication, and device analysis. The aim of the CREATE Lab is to support the development of next-generation 3D tissues and disease models for use in biomedical research and regenerative medicine and promoting cutting-edge interdisciplinary research.
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Queen Mary's new Centre for Predictive in vitro Models (CPM) represents multidisciplinary research focusing on the development and use of predictive in vitro models and next generation engineered tissues. This incorporates a wide range of model systems including 2D and 3D cell culture models, organoids, microphysiological systems, organ-on-a-chip technology, and other types of in vitro model. Researchers across Queen Mary are using these in vitro models to examine fundamental hypotheses around health and disease and to test new therapeutic strategies including pharmaceuticals, regenerative medicine techniques, medical devices and biomaterials. This research is supported by bioengineers, such as Dr John Connelly, who are developing these complex in vitro models and the underpinning technology which includes aspects of microfluidics, biomaterials, mechanobiology, computational modelling, micromanufacture and 3D printing. Queen Mary also has a major new strategic collaboration with the internationally leading organs-on-chips company, Emulate. Together we have established the QM+Emulate Organs-on-Chips Centre which provides unique access for academia and industry to Emulate's organ-on-a-chip platforms with full technical and scientific support.
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Queen Mary's interdisciplinary NanoVision Centre incorporates a complementary suite of advanced microscopes, combining different techniques together in unique ways for the first time in the UK. Within a single instrument the team combine a scanning electron microscope (SEM) that uses a high energy beam of electrons to image and investigate the structure of materials at a very small scale; with a scanning probe microscope (SPM) that uses a tiny physical probe tip that is moved over the sample in order to 'feel' the surface. This gives the team an unprecedented opportunity to examine how complex systems such as biological tissues behave in conditions close to their natural state. Visualising soft and biological matter is a particular strength of the Centre, using the latest in environmental microscopy techniques. The NanoVision Centre builds on Queen Mary's reputation for high quality interdisciplinary research, bringing together leading scientists and advanced technologies to support research across the institution. The new capabilities will facilitate medical researchers to reveal the interactions of chromosomes in the nucleus of cancer cells, present exciting opportunities to develop the next generation of high performance nanomaterials and many other applications.