Unzipping your genes

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15 May 2018

Time: 7:00 - 10:00pm
Venue: The Crown Tavern 43 Clerkenwell Green, London EC1R 0EG

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We’re all made up the same building blocks of life – our DNA, yet each and every one of us is unique. Our genes are crucial for determining our disease susceptibility and response to medication. Sarah will introduce us to the concept of genome instability and how this can be hijacked by cancer cells. With the evolution of genome sequencing, the era of personalized medicine could just be around the corner. Kate will address how healthcare might be about to change. 

Genome Sequencing: the missing link to personalised healthcare?

Dr Kate Witkowska (Commercial Partnerships Manager at Genomics England) 
The cost of a complete human genome sequence will soon be less than that of a Prada purse, becoming an attractive tool for disease prediction. Unlike a fashionable gadget, a genome sequence can be everlasting in its utility, used to assess multiple treatment options throughout a person’s life. Informatics tools linking patient records and genomic information offer to transform healthcare. Come to this Pint of Science talk to find out whether precision medicine is just around the corner!

Chromosome Cocktails – How and Why do Cancer Cells Mix their Genetic Material?

Dr Sarah McClelland (Lecturer, Barts Cancer Institute, Queen Mary University of London) 
Our genetic blueprint - our DNA - is an incredibly long string of letters. Each of the billions of cells in our body amazingly contains its own personal copy of this massive blueprint. This is possible thanks to amazing feats of structural engineering; chromosomes. I will introduce these amazing structures and describe the ongoing journey of discovery, started a century ago, of how cancer cells mix and match their chromosomes seemingly at will. Lastly I’ll explain some of the current exciting work in our laboratory, and how we’re learning more every day about the secret life of chromosomes.