Inaugural Lecture - Professor Norbert Avril

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24 May 2011

Time: 5:30pm
Venue: Willoughby Lecture Theatre, Charterhouse Square, London

The Warburg effect describes the observation that cancer cells exhibit glycolysis with lactate secretion and mitochondrial respiration even in the presence of oxygen. Warburg's hypothesis was postulated by the Nobel laureate Otto Heinrich Warburg in 1924.
The concept of Positron Emission Tomography (PET) was introduced in the late 1950s. The medical use of PET gained momentum with the development of labelled 2-fluorodeoxy-D-glucose (FDG) in the midseventies, which allows the visualisation of tissue glucose metabolism within the human body.
In this lecture, Professor Avril will demonstrate the evolution of clinical indications for PET imaging of
cancer and show its potential for future applications. Professor Norbert Avril grew up in the south western part of Germany and studied Pharmacy and Medicine at the Ruprecht Karl University of Heidelberg and the Ludwig Maximilian University of Munich. He trained in Nuclear Medicine at the Klinikum rechts der Isar, University of Technology in Munich. After a research fellowship (1995-97) at Memorial Sloan-Kettering Cancer Center in New York, he returned as academic Nuclear Medicine Consultant to Munich before he became in 2002 Chief of the Division of Nuclear Medicine at the University of Pittsburgh, USA. In 2005 he joined Queen Mary to develop a PET Oncology programme at Barts Cancer Institute and Barts and the London NHS Trust. His particular interests are new
clinically applicable molecular imaging strategies to optimise cancer treatments. He was awarded Professor of Nuclear Medicine in August 2010.

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