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Completed Studies

This section lists studies that PCTU has been involved in that have been completed and published.

Study Acronym Calcitriol 
Study Title                                    

A randomised control trial to test whether active vitamin D can improve the clinical response to steroids in asthmatic patients.

PCTU Ref 0024               
Chief Investigator

Prof Christopher Corrigan

 
Publications  

 

Study Acronym Chronic Constipation                             
Study Title                           Development of a UK evidence-based algorithm for management of chronic constipation
PCTU Ref P100
Chief Investigator  Professor Charles Knowles, Queen Mary University of London 
Publications

 

 

 

Study Acronym  Comm Skill/ Psychosis                                                                           
Study Title Developing and piloting a new intervention to improve psychiatrist-patient communication about psychosis
PCTU Ref                            P019
Chief Investigators  Professor Rose McCabe, City University of London 
Publications  

 

Study Acronym ComQuol                                                           
Study Title                                                                                         A pilot trial to assess the effect of a structured COMmunication approach on QUality Of Life in secure mental health settings                                                           
PCTU Ref             P018                             
Chief Investigator  Dr. Douglas MacInnes, Canterbury Christ Church University
Publications

MacInnes D, Kinane C, Parrott J, Mansfield J, Craig T, Eldridge S, Marsh I, Chan C, Hounsome N, Harrison G, Priebe S. A pilot cluster randomised trial to assess the effect of a structured communication approach on quality of life in secure mental health settings: The Comquol Study. BMC Psychiatry 2016;16:335.

MacInnes D, Kinane C, Beer D, Parrott J, Craig T, Eldridge S, Marsh I, Krotofil J, Priebe S. Study to assess the effect of a structured communication approach on quality of life in secure mental health settings (Comquol): study protocol for a pilot cluster randomized trial. Trials 2013;14:257.

 

Study Acronym CONFIDeNT                                                         
Study Title                             CONtrol of Faecal Incontinence using Distal NeuromodulaTion                                     
PCTU Ref P028
Chief Investigator  Professor Charles Knowles, Queen Mary University of London
Publications

Knowles CH, Horrocks EJ, Stevens N, Norton C, Eldridge S. The CONFIDeNT trial - Authors' reply. Lancet 2016;387:644-5. 

 

Study Acronym COPERS                                                              
Study Title                                                  COping with persistent Pain, Effectiveness Research for Self-management: a randomised controlled trial  
PCTU Ref             P054                           
Chief Investigator  Professor Stephanie Taylor, Queen Mary University of London
Publications

Taylor SJ, Carnes D, Homer K, Kahan BC, Hounsome N, Eldridge S, Spencer A, Pincus T, Rahman A, Underwood M. Novel Three-Day, Community-Based, Nonpharmacological Group Intervention for Chronic Musculoskeletal Pain (COPERS): A Randomised Clinical Trial. PLoS Med 2016;13:e1002040. 

Taylor SJC, Carnes D, Homer K, Pincus T, Kahan BC, Hounsome N, Eldridge S, Spencer A, Diaz-Ordaz K, Rahman A, Mars TS, Foell J, Griffiths CJ, Underwood MR. Improving the self-management of chronic pain: COping with persistent Pain, Effectiveness Research in Self-management (COPERS). Programme Grants for Applied Research 2016;4:14.

Kahan BC, Diaz-Ordaz K, Homer K, Carnes D, Underwood M, Taylor SJ, Bremner SA, Eldridge S. Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial. Trials 2014;15:59

Carnes D, Taylor SJ, Homer K, Eldridge S, Bremner S, Pincus T, Rahman A, Underwood M. Effectiveness and cost-effectiveness of a novel, group self-management course for adults with chronic musculoskeletal pain: study protocol for a multicentre, randomised controlled trial (COPERS). BMJ Open 2013;3:

 

Study Acronym  DAPPA                                              
Study Title                             

Spot protein creatinine ratio (SPCr) and spot albumin creatinine ratio (SACr) in the assessment of pre-eclampsia: A diagnostic accuracy study with decision analytic model based economic evaluation and acceptability analysis

PCTU Ref P071
Chief Investigator  Dr Elizabeth Ball, Queen Mary University of London
Publications  

 

Study Acronym EMPiRE                                                            
Study Title                              AntiEpileptic drug Monitoring in PREgnancy: an evaluation of effectiveness, cost-effectiveness and acceptability of monitoring strategies                                                                           
PCTU Ref             P067                          
Chief Investigator  Professor Khalid Khan, Queen Mary University of London
Publications

Thangaratinam S, Marlin N, Newton S, Weckesser A, Bagary M, Greenhill L, Rikunenko R, D'Amico M, Rogozinska E, Kelso A, Hard K, Coleman J, Moss N, Roberts T, Middleton L, Dodds J, Pullen A, Eldridge S, Pirie A, Denny E, McCorry D, Khan KS. AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies. Health Technol Assess 2018;22:1-152. https://doi.org/10.3310/hta22230

 

 

Study Acronym EPOCH                                                           
Study Title                            

Enhanced Peri-Operative Care for High-risk patients (EPOCH) Trial:

A stepped wedge cluster randomised trial of a quality improvement intervention for patients undergoing emergency laparotomy                                                                      

PCTU Ref             P111                       
Chief Investigator  Professor Rupert Pearse, Queen Mary University of London
Publications  

 

Study Acronym EPOS                                                             
Study Title                                                                               

Effective Patient-Clinician Communication in Community Mental Health Care 

PCTU Ref             P026                              
Chief Investigator  Professor Stefan Priebe, University College London
Publications  

 

Study Acronym  FINS Active Case Finding                                                                   
Study Title                         

Improving Continence in people with inflammatory bowel disease: active-finding and a randomised controlled trial

PCTU Ref P143
Chief Investigator  Professor Christine Norton, King's College London
Publications

Norton C, Dibley LB, Hart A, Duncan J, Emmanuel A, Knowles CH, Stevens N, Terry H, Verjee A, Kerry S, Hounsome N. Faecal incontinence intervention study (FINS): self-management booklet information with or without nurse support to improve continence in people with inflammatory bowel disease: study protocol for a randomized controlled trial. Trials 2015;16:444. 

 

Study Acronym GEM                                                         
Study Title                                  Randomised trial of a guided e-learning health promotion intervention for managers based on management standards for the improvement of employee wellbeing and reduction of sickness absence
PCTU Ref P084
Chief Investigator  Professor Stephen A Stansfeld, Queen Mary University of London 
Publications

Stansfeld SA, Berney L, Bhui K, Chandola T, Costelloe C, Hounsome N, Kerry S, Lanz D, Russell J. Pilot study of a randomised trial of a guided e-learning health promotion intervention for managers based on management standards for the improvement of employee well-being and reduction of sickness absence: the GEM (Guided E-learning for Managers) study. Public Health Research 2015;3:9.

Stansfeld SA, Kerry S, Chandola T, Russell J, Berney L, Hounsome N, Lanz D, Costelloe C, Smuk M, Bhui K. Pilot study of a cluster randomised trial of a guided e-learning health promotion intervention for managers based on management standards for the improvement of employee well-being and reduction of sickness absence: GEM Study. BMJ Open 2015;5:e007981.

 

 

Study Acronym HABSelect                                                              
Study Title                                                  Selection of sperm for Intracytoplasmic Sperm Injection (ICSI) by prior hyaluronic acid binding: improving the outcomes of Assisted Conception procedures and reducing miscarriage rates. 
PCTU Ref             P095                             
Chief Investigator  Dr David Miller, University of Leeds
Publications  

 

Study Acronym             HEPFree                                                                                                                          
Study Title                              Chronic viral hepatitis in ethnic minorities. Strategies to prevent the predicted increase in mortality                                        
PCTU Ref P047
Chief Investigator Professor Graham Foster, Queen Mary University of London
Publications

Flanagan S, Kunkel J, Appleby V, Eldridge SE, Ismail S, Moreea S, Griffiths C, Walton R, Pitt M, Salmon A, Madurasinghe V, Barnes E, Simms E, Agarwal K, Foster GR. Case finding and therapy for chronic viral hepatitis in primary care (HepFREE): a cluster-randomised controlled trial. Lancet Gastroenterol Hepatol 2018; https://doi.org/10.1016/S2468-1253(18)30318-2 

 

Study Acronym IMPART                                                       
Study Title                           

IMPlementing IMProved Asthma self-management as Routine Treatment

PCTU Ref P162
Chief Investigator  Dr.Hilary Pinnock , Queen Mary University of London
Publications  

 

Study Acronym ImprovE                                                        
Study Title                            Exploring shared decision- making practices during involuntary hospital treatment 
PCTU Ref P191
Chief Investigator  Dr. Domenico Giacco, Queen Mary University of London
Publications  

 

Study Acronym                           iWIP                                                      
Study Title                        Effects of weight management interventions on maternal and fetal outcomes in pregnancy: Individual patient data (IPD)
meta analysis of randomised trials and model based economic evaluation                                            
PCTU Ref                                  P105
Chief Investigator  Professor Shakila Thangaratinam, Queen Mary University of London
Publications

Rogozinska E, Marlin N, Betran AP, Astrup A, Bogaerts A, Cecatti JG, Devlieger R, Dodd JM, El Beltagy N, Facchinetti F, Geiker NRW, Guelfi KJ, Haakstad LAH, Harrison CL, Hauner H, Jensen DM, Kinnunen TI, Khoury J, Luoto R, McAuliffe F, Motahari N, Morkved S, Owens J, Perales M, Petrella E, Phelan S, Poston L, Rauh K, Renault KM, Sagedal LR, Salvesen KA, Shen GX, Shub A, Scudeller T, Surita FG, Stafne SN, Teede H, Tonstad S, van Poppel MNM, Vinter CA, Vistad I, Yeo S, Dodds J, Kerry S, Jackson L, Barton P, Molyneaux E, Martin AA, Rayanagoudar G, Ruifrok AE, Roberts T, de Groot CJM, Coomarasamy A, Mol BWJ, Zamora J, Khan KS, Riley RD, Thangaratinam S. Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials The International Weight Management in Pregnancy (i-WIP) Collaborative Group. BMJ 2017;358: https://doi.org/10.1136/bmj.j3119 

 

Study Acronym  LPE/Homeless                                             
Study Title                                                  

Discharge planning for the homeless, examining The London Pathway. Does a GP led discharge team reduce the in-patient burden and improve quality of care?

PCTU Ref P082
Chief Investigator  Professor Graham Foster, Queen Mary University of London
Publications Hewett N, Buchman P, Musariri J, Sargeant C, Johnson P, Abeysekera K, Grant L, Oliver EA, Eleftheriades C, McCormick B, Halligan A, Marlin N, Kerry S, Foster GR. Randomised controlled trial of GP-led in-hospital management of homeless people ('Pathway'). Clin Med 2016;16:223-9. 

  

Study Acronym             MEMPHIS                                                                               
Study Title                              A smartphone app using psychological approaches for women with chronic pelvic pain: a randomised feasibility trial                                   
PCTU Ref P156
Chief Investigator Dr. Elizabeth Ball, Queen Mary University of London
Publications  

 

Study Acronym                                                   NESS 
Study Title                               

Effectiveness and Cost-Effectiveness of Body Psychotherapy in the Treatment of Negative Symptoms of Schizophrenia – A Multi-Centre Randomised Controlled Trial

                   
PCTU Ref P013
Chief Investigator  Professor Stefan Priebe, Queen Mary University of London
Publications

Priebe S, Savill M, Wykes T, Bentall R, Lauber C, Reininghaus U, McCrone P, Mosweu I, Bremner S, Eldridge S, Rohricht F. Clinical effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia: a multicentre randomised controlled trial. Health Technol Assess 2016;20:vii-xxiii, 1-100.

Priebe S, Savill M, Wykes T, Bentall RP, Reininghaus U, Lauber C, Bremner S, Eldridge S, Rohricht F. Effectiveness of group body psychotherapy for negative symptoms of schizophrenia: multicentre randomised controlled trial. Br J Psychiatry 2016;209:54-61.

Priebe S, Savill M, Reininghaus U, Wykes T, Bentall R, Lauber C, McCrone P, Rohricht F, Eldridge S. Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia--a multi-centre randomised controlled trial. BMC Psychiatry 2013;13:26.

 

Study Acronym Oedipus
Study Title                                                Effect of an Education Programme for South Asians with Asthma and Their Clinicians: A Cluster Randomised Controlled Trial                                                                                        
PCTU Ref O014
Chief Investigator  Professor Chris Griffiths, Queen Mary University of London 
Publications

Griffiths C, Bremner S, Islam K, Sohanpal R, Vidal DL, Dawson C, Foster G, Ramsay J, Feder G, Taylor S, Barnes N, Choudhury A, Packe G, Bayliss E, Trathen D, Moss P, Cook V, Livingstone AE, Eldridge S. Effect of an Education Programme for South Asians with Asthma and Their Clinicians: A Cluster Randomised Controlled Trial (OEDIPUS). PLoS One 2016;11:e0158783 

 

Study Acronym       OPERA
Study Title                                  Older People's Exercise Intervention in Residential and Nursing Accommodation                                                                                      
PCTU Ref P057
Chief Investigator   Dr. Stephanie Taylor, Queen Mary University of London
Publications

Underwood M, Lamb SE, Eldridge S, Sheehan B, Slowther A, Spencer A, Thorogood M, Atherton N, Bremner SA, Devine A, Diaz-Ordaz K, Ellard DR, Potter R, Spanjers K, Taylor SJ. Exercise for depression in care home residents: a randomised controlled trial with cost-effectiveness analysis (OPERA). Health Technol Assess 2013;17:1-281. 

Underwood M, Eldridge S, Lamb S, Potter R, Sheehan B, Slowther AM, Taylor S, Thorogood M, Weich S. The OPERA trial: protocol for a randomised trial of an exercise intervention for older people in residential and nursing accommodation. Trials 2011;12:27.

 

Study Acronym PACE-UP
Study Title                                                

Randomised controlled trial of a pedometer-based walking intervention with and without practice nurse support in primary care patients aged 45-74 years                                                     

PCTU Ref P059
Chief Investigator  Dr. Tess Harris, St. George's University of London 
Publications

Anokye N, Fox-Rushby J, Sanghera S, Cook DG, Limb E, Furness C, Kerry SM, Victor CR, Iliffe S, Ussher M, Whincup PH, Ekelund U, deWilde S, Harris T. Short-term and long-term cost-effectiveness of a pedometer-based exercise intervention in primary care: a within-trial analysis and beyond-trial modelling. BMJ Open 2018;8:e021978. https://doi.org/10.1136/bmjopen-2018-021978 

Furness C, Howard E, Limb E, Cook DG, Kerry S, Wahlich C, Victor C, Ekelund U, Iliffe S, Ussher M, Whincup P, Fox-Rushby J, Ibison J, DeWilde S, Harris T. Relating process evaluation measures to complex intervention outcomes: findings from the PACE-UP primary care pedometer-based walking trial. Trials 2018;19:58. https://doi.org/10.1186/s13063-017-2428-z 

Harris T, Kerry SM, Limb ES, Furness C, Wahlich C, Victor CR, Iliffe S, Whincup PH, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, DeWilde S, McKay C, Cook DG. Physical activity levels in adults and older adults 3-4 years after pedometer-based walking interventions: Long-term follow-up of participants from two randomised controlled trials in UK primary care. PLoS Med 2018;15:e1002526. https://doi.org/10.1371/journal.pmed.1002526

Kerry SM, Morgan KE, Limb E, Cook DG, Furness C, Carey I, DeWilde S, Victor CR, Iliffe S, Whincup P, Ussher M, Ekelund U, Fox-Rushby J, Ibison J, Harris T. Interpreting population reach of a large, successful physical activity trial delivered through primary care. BMC Public Health 2018;18:170. https://doi.org/10.1186/s12889-018-5034-4

Normansell R, Holmes R, Victor C, Cook DG, Kerry S, Iliffe S, Ussher M, Fox-Rushby J, Whincup P, Harris T. Exploring non-participation in primary care physical activity interventions: PACE-UP trial interview findings.Trials 2016;17:178

Harris T, Kerry SM, Victor CR, Shah SM, Iliffe S, Ussher M, Ekelund U, Fox-Rushby J, Whincup P, David L, Brewin D, Ibison J, DeWilde S, Limb E, Anokye N, Furness C, Howard E, Dale R, Cook DG. PACE-UP (Pedometer and consultation evaluation--UP)--a pedometer-based walking intervention with and without practice nurse support in primary care patients aged 45-75 years: study protocol for a randomised controlled trial. Trials 2013;14:418.

 

Study Acronym

PREP
Study Title

Development and validation of a Prediction model for Risk of complications in Early onset Pre-eclampsia                                                             

PCTU Ref P066
Chief Investigator Professor Khalid Khan, Queen Mary University of London
Publications

Thangaratinam S, Allotey J, Marlin N, Dodds J, Cheong-See F, von Dadelszen P, Ganzevoort W, Akkermans J, Kerry S, Mol BW, Moons KG, Riley RD, Khan KS. Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models. BMC Med 2017;15:68. https://doi.org/10.1186/s12916-017-0827-3

Thangaratinam S, Allotey J, Marlin N, Mol BW, Von Dadelszen P, Ganzevoort W, Akkermans J, Ahmed A, Daniels J, Deeks J, Ismail K, Barnard AM, Dodds J, Kerry S, Moons C, Riley RD, Khan KS. Development and validation of Prediction models for Risks of complications in Early-onset Pre-eclampsia (PREP): a prospective cohort study. Health Technol Assess 2017;21:1-100. https://doi.org/10.3310/hta21180

 

Study Acronym             PROMISE                                                                                                                                               
Study Title Patient Reported Outcome MeasureS using electronic informed consent and data capture – developing methods and infrastructure                                                                         
PCTU Ref P265
Chief Investigator
Dr Richard Hooper, Queen Mary University of London
Professor Charles Knowles, Queen Mary University of London
                                                        
Publications  

 

Study Acronym                 QuEST
Study Title                                            Quality and Effectiveness of Supported Tenancies for people with mental health problems
PCTU Ref P080
Chief Investigator  Dr Helen Killaspy, University College London
Publications  

 

Study Acronym                            RHIVA-2                                                         
Study Title            

Effectiveness of HIV screening in Primary Care:

A cluster RCT and economic analysis

PCTU Ref P007
Chief Investigator  Professor Chris Griffiths, Queen Mary University of London 
Publications Leber W, McMullen H, Bremner S, Kerry S, Millett D, Mguni S, Awosika D, Creighton S, Figueroa J, Hart G, Sampson M, Anderson J, Griffiths C. Can point of care HIV testing in primary care increase identification of HIV? The RHIVA 2 cluster randomised controlled trial - update. HIV Medicine 2012;13:7-7. 

 

Study Acronym                                SALVO                                                         
Study Title             A Randomised Controlled Trial of Intra-Operative Cell Salvage during Caesarean Section in Women at Risk of Haemorrhage
PCTU Ref P079
Chief Investigator  Professor Khalid Khan, Queen Mary University of London
Publications

Khan KS, Moore P, Wilson M, Hooper R, Allard S, Wrench I, Roberts T, McLoughlin C, Beresford L, Geoghegan J, Daniels J, Catling S, Clark VA, Ayuk P, Robson S, Gao-Smith F, Hogg M, Jackson L, Lanz D, Dodds J. A randomised controlled trial and economic evaluation of intraoperative cell salvage during caesarean section inwomen at risk of haemorrhage: the SALVO (cell SALVage in Obstetrics) trial. Health Technol Assess 2018;22:1-88. https://doi.org/10.3310/hta22020

Khan KS, Moore PAS, Wilson MJ, Hooper R, Allard S, Wrench I, Beresford L, Roberts TE, McLoughlin C, Geoghegan J, Daniels JP, Catling S, Clark VA, Ayuk P, Robson S, Gao-Smith F, Hogg M, Lanz D, Dodds J, group Ss. Cell salvage and donor blood transfusion during cesarean section: A pragmatic, multicentre randomised controlled trial (SALVO). PLoS Med 2017;14:e1002471. https://doi.org/10.1371/journal.pmed.1002471 

 

Study Acronym                 SNSvsPTNS     
Study Title                                                                                 

A Randomised pilot and feasability study of sacral and percutaneous tibial nerve stimulation for faecal incontinence.                                                                                                                                                                                       

PCTU Ref P044
Chief Investigator  Professor Charles Knowles, Queen Mary University of London
Publications

McAlees E, Vollebregt PF, Stevens N, Dudding TC, Emmanuel AV, Furlong PL, Hamdy S, Hooper RL, Jones JFX, Norton C, O'Connell PR, Scott SM, Knowles CH. Efficacy and mechanism of sub-sensory sacral (optimised) neuromodulation in adults with faecal incontinence: study protocol for a randomised controlled trial. Trials 2018;19:336. https://doi.org/10.1186/s13063-018-2689-1

Thin NN, Taylor SJ, Bremner SA, Emmanuel AV, Hounsome N, Williams NS, Knowles CH. Randomized clinical trial of sacral versus percutaneous tibial nerve stimulation in patients with faecal incontinence. Br J Surg 2015;102:349-58. 

 

Study Acronym                  SWAP                                                           
Study Title                                                                                  

A peer-support weight action programme to supplement brief advice in general practice                                                                                                                

PCTU Ref P064
Chief Investigator 

Dr Hayden McRobbie, Queen Mary University of London

Publications  

 

Study Acronym                          ViDiAS                                                           
Study Title             Randomised, Multi-Centre, Double-Blind, Placebo-
Controlled Trial of Vitamin D Supplementation in Adult and Adolescent Patients with Asthma              
PCTU Ref P056
Chief Investigator 
Dr. Adrian Martineau, Queen Mary University of London
Publications

Jolliffe DA, Greenberg L, Hooper RL, Griffiths CJ, Camargo CA, Jr., Kerley CP, Jensen ME, Mauger D, Stelmach I, Urashima M, Martineau AR. Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data. Lancet Respir Med 2017;5:881-890. https://doi.org/10.1016/S2213-2600(17)30306-5 

 

Study Acronym                                ViDiCO                                           
Study Title     Randomised, Multi-Centre, Double-Blind, Placebo-
Controlled Trial of Vitamin D Supplementation in Patients with Chronic Obstructive Pulmonary Disease                                                                                        
PCTU Ref P056
Chief Investigator  Dr. Adrian Martineau, Queen Mary University of London
Publications  

 

Study Acronym                                ViDiFlu                                  
Study Title     Trial Of Vitamin D Supplementation for the Prevention of Influenza and Other Respiratory Infections
PCTU Ref P056
Chief Investigator  Dr. Adrian Martineau, Queen Mary University of London
Publications

 

 

Study Acronym                                Vit D IPD                                      
Study Title     Vitamin D supplementation to prevent acute respiratory infection: individual
patient data meta-analysis of randomised controlled trials                                                                                        
PCTU Ref P132
Chief Investigator  Dr. Adrian Martineau, Queen Mary University of London
Publications

Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D, Ginde AA, Goodall EC, Grant CC, Griffiths CJ, Janssens W, Laaksi I, Manaseki-Holland S, Mauger D, Murdoch DR, Neale R, Rees JR, Simpson S, Jr., Stelmach I, Kumar GT, Urashima M, Camargo CA, Jr. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ 2017;356:i6583. https://doi.org/10.1136/bmj.i6583  

 

 

Study Acronym                                VOLUME                                       
Study Title     An Exploratory Randomised Controlled Trial Assessing Volunteering in Mental Health Care for People with Psychosis                                                                                         
PCTU Ref P090
Chief Investigator  Professor Stefan Priebe, Queen Mary University of London
Publications

Priebe S, Pavlickova H, Eldridge S, Golden E, McCrone P, Ockenden N, Pistrang N, King M. Effectiveness of one-to-one volunteer support for patients with psychosis: protocol of a randomised controlled trial. BMJ Open 2016;6:e011582. 

 

 

Study Acronym                                WAIT                                             
Study Title     Parent-Determined Oral Montelukast Therapy For Preschool Wheeze                                                                                       
PCTU Ref P003
Chief Investigator  Professor Jonathan Grigg, Queen Mary University of London
Publications

Nwokoro C, Pandya H, Turner S, Eldridge S, Griffiths CJ, Vulliamy T, Price D, Sanak M, Holloway JW, Brugha R, Koh L, Dickson I, Rutterford C, Grigg J. Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial. Lancet Respir Med 2014;2:796-803. 

 

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