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Pragmatic Clinical Trials Unit

Mental Health

A major strength of the PCTU is the evaluation of complex interventions in mental health care. This includes completed trials on innovative interventions such as body psychotherapy in the treatment of negative symptoms of schizophrenia, using financial incentives to improve adherence to medication, and testing the DIALOG+ intervention in community care and forensic settings. Ongoing work includes feasibility and full trials on effects of support housing, new interventions to improve patients' quality of life through enhancing their social networks, testing DIALOG+ in patients with chronic depression, and evaluating the effects of peer support. 

 Most of the studies require complex designs that are challenging to implement. The PCTU has an especially positive track record in completing these studies successfully.

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