Blizard Institute - Barts and The London

National Centre for the Replacement Refinement and Reduction of Animals in Research PhD studentship now available

Dr Yung-Yao Lin from the Centre for Genomics and Child Health at the Blizard Institute has been awarded funding to offer a PhD studentship in ‘3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery’ by the National Centre for the Replacement Refinement and Reduction of Animals in Research (NC3Rs)

20 December 2019

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Laboratory at the Blizard Institute

NC3Rs has announced 16 new PhD studentships, which embed the 3Rs (Replacement, Refinement and Reduction of animals in research) in the training of early career researchers across a range of disciplines.

As part of this funding, Principal Investigator Dr Yung-Yao Lin has received a £90,000 grant to offer a PhD studentship in ‘3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery’, which focuses on the Replacement and Reduction aspects of the 3Rs. Find out more about the studentship.

The awards are made directly to the principal investigators; interested students should contact Dr Yung-Yao Lin directly to enquire and apply. The secondary supervisor will be Dr John Connelly from the Centre for Cell Biology and Cutaneous Research at the Blizard Institute.

More information

Human iPSC-derived myogenic progenitors in combination with 3D bio-printing technologies can provide human-specific platforms critically needed for elucidating disease mechanisms and facilitating drug discovery. Importantly, our experimental paradigms are broadly applicable to any muscle disease. This multidisciplinary project will have a significant impact on developing novel human pre-clinical models and replacing/reducing the use of mouse models in muscular dystrophy research. More.