Skip to main content
Wolfson Institute of Preventive Medicine (WIPM)

Publications

We maintain an archive of past and current publications which can be searched by clicking on the links to the left or by using the search bar below to search by key word, author name, journal name or year of publication.

Our most recent publications are listed below.

AuthorsPublication SummaryJournalYears
Bothongo PL,Jitlal M,Parry E,Foote IF,Waters S,Dobson R,Noyce AJ,Bestwick JP,Marshall CR,Unit WIOPMPN Ethnic and socioeconomic determinants of dementia risk: A nested case‐control study in the population of East London. vol.16, (S10) paginationBegin.
10.1002/alz.037869
Alzheimer's & Dementia 2020
Foote IF,Jacobs BM,Noyce AJ,Korszun A,Bhui KS,Marshall CR Exploring the shared genetic architecture of modifiable risk factors and related endophenotypes of Alzheimer’s disease: A genomic SEM study. vol.16, (S2) paginationBegin.
10.1002/alz.045164
Alzheimer's & Dementia 2020
Curtis D,Bandyopadhyay S Mini-review: Role of the PI3K/Akt pathway and tyrosine phosphatases in Alzheimer's disease susceptibility. vol.volume, (issue) paginationBegin.
10.1111/ahg.12410
Annals of Human Genetics 2020
Guelfi S,D’Sa K,Botía JA,Vandrovcova J,Reynolds RH,Zhang D,Trabzuni D,Collado-Torres L,Thomason A,Quijada Leyton P,Gagliano Taliun SA,Nalls MA,Noyce AJ,Nicolas A,Cookson MR,Bandres-Ciga S,Gibbs JR,Hernandez DG,Singleton AB,Reed X,Leonard H,Blauwendraat C,Faghri F,Bras J,Guerreiro R,Tucci A,Kia DA,Houlden H,Plun-Favreau H,Mok KY,Wood NW,Lovering R,R’Bibo L,Rizig M,Chelban V,Tan M,Morris HR,Middlehurst B,Quinn J,Billingsley K,Holmans P,Kinghorn KJ,Lewis P,Escott-Price V,Williams N,Foltynie T,Brice A,Danjou F,Lesage S,Corvol JC,Martinez M Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information. vol.11, (1) paginationBegin.
10.1038/s41467-020-14483-x
Nature Communications 2020
Benhamou E,Marshall CR,Russell LL,Hardy CJD,Bond RL,Sivasathiaseelan H,Greaves CV,Friston KJ,Rohrer JD,Warren JD,Razi A The neurophysiological architecture of semantic dementia: spectral dynamic causal modelling of a neurodegenerative proteinopathy. vol.10, (1) paginationBegin.
10.1038/s41598-020-72847-1
Scientific Reports 2020
Curtis D Do damaging variants of SLC6A9, the gene for the glycine transporter 1 (GlyT-1), protect against schizophrenia?. vol.volume, (issue) 150.
10.1097/YPG.0000000000000260
Psychiatric Genetics 2020
Iwaki H,Blauwendraat C,Leonard HL,Makarious MB,Kim JJ,Liu G,Maple-Grødem J,Corvol JC,Pihlstrøm L,van Nimwegen M,Smolensky L,Amondikar N,Hutten SJ,Frasier M,Nguyen KDH,Rick J,Eberly S,Faghri F,Auinger P,Scott KM,Wijeyekoon R,Van Deerlin VM,Hernandez DG,Gibbs RJ,Day-Williams AG,Brice A,Alves G,Noyce AJ,Tysnes OB,Evans JR,Breen DP,Estrada K,Wegel CE,Danjou F,Simon DK,Andreassen OA,Ravina B,Toft M,Heutink P,Bloem BR,Weintraub D,Barker RA,Williams-Gray CH,van de Warrenburg BP,Van Hilten JJ,Scherzer CR,Singleton AB,Nalls MA Differences in the Presentation and Progression of Parkinson's Disease by Sex. vol.volume, (issue) paginationBegin.
10.1002/mds.28312
Movement Disorders 2020
Auger SD,Jacobs BM,Dobson R,Marshall CR,Noyce AJ Big data, machine learning and artificial intelligence: a neurologist's guide.. vol.volume, (issue) paginationBegin.
10.1136/practneurol-2020-002688
Pract Neurol 2020
Auger S,Jacobs B,Dobson R,MARSHALL C,Noyce A Navigating a world of big data, machine learning and artificial intelligence: a neurologist's guide. vol.volume, (issue) paginationBegin.
10.1136/practneurol-2020-002688
Practical Neurology 2020
Jacobs B,Belete D,Bestwick J,Blauwendraat C,Bandres-Ciga S,Heilbron K,Dobson R,International Parkinson’s Disease Genomics Consortium (IPDGC) null,Nalls M,Singleton A,Hardy J,Giovannoni G,Lees A,Schrag A,Noyce A Parkinson’s disease determinants, prediction and gene-environment interactions in the UK Biobank. vol.91, (issue) 1046.
10.1136/jnnp-2020-323646
Journal of Neurology, Neurosurgery and Psychiatry 2020
Jimenez DA,Bond RL,Requena-Komuro MC,Sivasathiaseelan H,Marshall CR,Russell LL,Greaves C,Moore KM,Woollacott IO,Shafei R,Hardy CJ,Rohrer JD,Warren JD Altered phobic reactions in frontotemporal dementia: A behavioural and neuroanatomical analysis. vol.130, (issue) 100.
10.1016/j.cortex.2020.05.016
Cortex 2020
Mencacci NE,Reynolds R,Ruiz SG,Vandrovcova J,Forabosco P,Sánchez-Ferrer A,Volpato V,Weale ME,Bhatia KP,Webber C,Hardy J,Botía JA,Ryten M,D'Sa K,Guelfi S,Mackenzie CA,Ramasamy A,Smith C,Trabzuni D,Noyce AJ,Kaiyrzhanov R,Middlehurst B,Kia DA,Tan M,Houlden H,Morris HR,Plun-Favreau H,Holmans P,Bras J,Quinn J,Mok KY,Kinghorn KJ,Billingsley K,Wood NW,Lewis P,Guerreiro R,Lovering R,R'Bibo L,Manzoni C,Rizig M,Escott-Price V,Chelban V,Foltynie T,Williams N,Shashakin C,Zharkinbekova N,Zholdybayeva E,Aitkulova A,Harvey K,Brice A,Danjou F Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders. vol.143, (9) 2771.
10.1093/brain/awaa217
Brain 2020
Cheong J,Goh Z,Marras C,Tanner C,Kasten M,Noyce A,Movement Disorders Society Epidemiology Study Group null The impact of COVID-19 on access to Parkinson’s disease medication. vol.volume, (issue) paginationBegin.
10.1002/mds.28293
Movement Disorders 2020
Jacobs B,Taylor T,Awad A,Baker D,Giovannoni G,Noyce A,Dobson R Summary-data-based mendelian randomisation prioritises potential druggable targets for Multiple Sclerosis. vol.volume, (issue) paginationBegin.
10.1093/braincomms/fcaa119
Brain Communications 2020
Curtis D Study of transgender patients: Conclusions are not supported by findings. vol.177, (8) 766.
10.1176/appi.ajp.2020.19111131
American Journal of Psychiatry 2020
Curtis D Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia. vol.volume, (issue) paginationBegin.
10.1016/j.ymgme.2020.07.009
Molecular Genetics and Metabolism 2020
Curtis D,Balloux F Editorial: Topical ethical issues in the publication of human genetics research. vol.84, (4) 313.
10.1111/ahg.12382
Annals of Human Genetics 2020
Johnson JCS,Jiang J,Bond RL,Benhamou E,Requena-Komuro MC,Russell LL,Greaves C,Nelson A,Sivasathiaseelan H,Marshall CR,Volkmer AP,Rohrer JD,Warren JD,Hardy CJD Impaired phonemic discrimination in logopenic variant primary progressive aphasia. vol.7, (7) 1252.
10.1002/acn3.51101
Annals of Clinical and Translational Neurology 2020
Curtis D Weighted burden analysis of exome-sequenced late onset alzheimer's cases and controls provides further evidence for involvement of psen1 and demonstrates role for pi3k/akt/gsk-3 beta signalling pathway. vol.63, (issue) S151.
doi
EUROPEAN PSYCHIATRY 2020
Balogha E,Chandlerc JC,Vargaa M,Tahounc M,Menyhárdf DK,Schaya G,Goncalvesi T,Hamard R,Légrádia R,Szekeresb Á,Gribouval O,Kletak R,Stanescuk H,Bockenhauerk D,Kertia A,Williamsm H,Kinslern V,Dio WL,Curtisp D,Kolatsi-Joannouc M,Hammidc H,Szocsq A,Perczel K,Makar E,Toldib G,Savaa F,Arrondelj C,Kardoss M,Finthas A,Hossaint A,D'Arcou F,Kaliakatsosv M,Koeglmeierw J,Mifsudx W,Moosajeey M,Faroz A,Jávorszkya E,Rudasq G,Saiede MH,Marzouke S,Kelenb K,Götzeb J,Reuszb G,Tulassay T,Dragont F,Molletj G,Motameny S,Thielebb H,Dorvalj G,Nörnberg P,Perczelf A Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis. vol.117, (26) 15137.
10.1073/pnas.2002328117
Proceedings of the National Academy of Sciences of the United States of America 2020
Noyce A Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease. vol.volume, (issue) paginationBegin.
10.1007/s00401-020-02181-3
Acta Neuropathologica 2020
Kamitaki N,Sekar A,Handsaker RE,de Rivera H,Tooley K,Morris DL,Taylor KE,Whelan CW,Tombleson P,Loohuis LMO,Ripke S,Neale BM,Corvin A,Walters JTR,Farh KH,Holmans PA,Lee P,Bulik-Sullivan B,Collier DA,Huang H,Pers TH,Agartz I,Agerbo E,Albus M,Alexander M,Amin F,Bacanu SA,Begemann M,Belliveau RA,Bene J,Bergen SE,Bevilacqua E,Bigdeli TB,Black DW,Bruggeman R,Buccola NG,Buckner RL,Byerley W,Cahn W,Cai G,Cairns MJ,Campion D,Cantor RM,Carr VJ,Carrera N,Catts SV,Chambert KD,Chan RCK,Chen RYL,Chen EYH,Cheng W Complement genes contribute sex-biased vulnerability in diverse disorders. vol.582, (7813) 577.
10.1038/s41586-020-2277-x
Nature 2020
Noyce A,Giovannoni G,Scheltens P,Berg D,Brown L,Dierickx K,Frisoni GB,Georges J,Hardy J,Heilbron K Time matters in brain health: how should society prepare for a growing population at risk of neurodegenerative diseases?. vol.27, (issue) 143.
doi
EUROPEAN JOURNAL OF NEUROLOGY 2020
Requena-Komuro MC,Marshall CR,Bond RL,Russell LL,Greaves C,Moore KM,Agustus JL,Benhamou E,Sivasathiaseelan H,Hardy CJD,Rohrer JD,Warren JD Altered Time Awareness in Dementia. vol.11, (issue) paginationBegin.
10.3389/fneur.2020.00291
Frontiers in Neurology 2020
Dobson R,Jitlal M,Marshall CR,Noyce AJ,Robson J,Cuzick J,Giovannoni G Ethnic and Socioeconomic Associations with Multiple Sclerosis Risk. vol.87, (4) 599.
10.1002/ana.25688
Annals of Neurology 2020
Blauwendraat C,Reed X,Krohn L,Heilbron K,Bandres-Ciga S,Tan M,Raphael Gibbs J,Hernandez DG,Kumaran R,Langston R,Bonet-Ponce L,Alcalay RN,Hassin-Baer S,Greenbaum L,Iwaki H,Leonard HL,Grenn FP,Ruskey JA,Sabir M,Ahmed S,Makarious MB,Pihlstrøm L,Toft M,van Hilten JJ,Marinus J,Schulte C,Brockmann K,Sharma M,Siitonen A,Majamaa K,Eerola-Rautio J,Tienari PJ,Pantelyat A,Hillis AE,Dawson TM,Rosenthal LS,Albert MS,Resnick SM,Ferrucci L,Morris CM,Pletnikova O,Troncoso J,Grosset D,Lesage S,Corvol JC,Brice A,Noyce AJ,Masliah E,Wood N,Hardy J,Shulman LM Erratum: Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia (Brain (2020) 143 (234-48) DOI: 10.1093/brain/awz350). vol.143, (3) e33.
10.1093/brain/awaa036
Brain 2020
Marshall CR,Warren JD Reply: Brain-behaviour associations and neural representations of emotions in frontotemporal dementia. vol.143, (3) E18.
10.1093/brain/awaa006
Brain 2020
Jacobs B,Noyce A,Hardy CJD,Warren J,Marshall C Estimating the causal effect of hearing loss on Alzheimer’s disease: a Mendelian randomisation study. vol.volume, (issue) paginationBegin.
10.1101/2020.02.25.20017525
journal 2020
Curtis D,Bakaya K,Sharma L,Bandyopadhyay S Weighted burden analysis of exome-sequenced late-onset Alzheimer's cases and controls provides further evidence for a role for PSEN1 and suggests involvement of the PI3K/Akt/GSK-3β and WNT signalling pathways. vol.volume, (issue) paginationBegin.
10.1111/ahg.12375
Annals of Human Genetics 2020
Dobson R,Noyce A,Giovannoni G,jacobs B BMI and low serum vitamin D are causal risk factors for Multiple Sclerosis: a Mendelian Randomisation study. vol.volume, (issue) paginationBegin.
10.1212/NXI.0000000000000662
Neurology, Neuroimmunology and Neuroinflammation 2020
Alexander M,CURTIS D LD scores are associated with differences in allele frequencies between populations but LD score regression can still distinguish confounding from polygenicity. vol.volume, (issue) paginationBegin.
10.1111/ahg.12370
Annals of Human Genetics 2020
Alarcón F,Maldonado JC,Cañizares M,Molina J,Noyce AJ,Lees AJ Motor Dysfunction as a Prodrome of Parkinson's Disease. vol.10, (3) 1067.
10.3233/JPD-191851
Journal of Parkinson's Disease 2020
Noyce A,International Parkinson’s Disease Genomics Consortium (IPDGC) null Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia. vol.volume, (issue) paginationBegin.
10.1093/brain/awz350
Brain: a journal of neurology 2020