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Wolfson Institute of Preventive Medicine (WIPM)

Technical evaluation of the Xpert assay in general screening population

Centre for Cancer Prevention

Funding Body:  Cepheid

Principal Investigator:  Professor Jack Cuzick,


In a manner similar to the Predictors studies we evaluated a new rapid result (60 minute) simple cartridge-based HPV test (Cepheid) in over 3,400 residual ThinPrep cervical screening samples.

The test was compared to the Roche Cobas test and the Qiagen Hybrid Capture 2 test


Performance of the Xpert HPV assay in women attending for cervical screening. Papillomavirus Research 2015; 1: 32-7; Cuzick J, Cuschieri K, Denton K, Hopkins M, Thorat M, Wright C, Cubie H, Moore C, Kleeman M, Austin J, Ashdown-Barr L, Hunt K, Cadman L.