A pragmatic randomised controlled trial of response to an invitation to self-sampling for human papillomavirus (HPV) versus repeat invitation for cervical screening in persistent non-responders in Newcastle upon Tyne. 3,000 women in the intervention group were sent an invitation to perform an HPV self-sample; 3,000 women in the comparator group were sent a further invitation to attend for cervical screening. The secondary objective was whether women with an abnormal result would attend for follow-up.
A further objective was to explore whether uptake of HPV self-testing would be higher in non-responders in the Newcastle area compared with non-responders in our previous trial carried out in an inner London area with a highly-mobile population.
This trial has now ended and the results have been published.
A randomized controlled trial in non-responders from Newcastle upon Tyne invited to return a self-sample for Human Papillomavirus testing versus repeat invitation for cervical screening. J Med Screen. 2015 Mar;22(1):28-37.
Cadman L, Wilkes S, Mansour D, Austin J, Ashdown-Barr L, Edwards R, Kleeman M, Szarewski A.