The following problems are being actively studied:
- Design and analysis of multi-arm clinical trials. There is particular interest in adaptive designs in which arms are dropped.
- Design and analysis of clinical trials with factorial designs to study multiple interventions in a single trial.
- Analysis of clinical trials subject to non-compliance and unplanned cross-over.
- Design of predictive biomarker trials to detect a qualitative interaction.
Phone: +44 (0) 20 7882 3531