The PANTERA study is evaluating the feasibility of aerobic exercise training as a novel primary therapy for men with early prostate cancer. In this randomised control trial (RCT) 50 men undergoing active surveillance for early prostate cancer will be randomised to a complex intervention of aerobic exercise training and behaviour change support for 12 months or to usual care.
The primary outcome will be the feasibility of the intervention including recruitment rate, adherence and attrition due to the intervention, loss to follow-up and adverse event rate. Feasibility outcomes will be assessed using standard methods for rates and proportions. Sample standard deviations of PSA will be obtained, to inform sample size calculations for a full-scale trial.
The PANTERA study is sponsored by Sheffield Hallam University.
Dr Liam Bourke
Tel: +44 (0)114 225 5396