Wolfson Institute of Preventive Medicine - Barts and The London

The 17th Wolfson Lecture "Clinical Applications of Genomic Medicine - what can we realistically expect?"

Professor Hugh Watkins
(Radcliffe Department of Medicine, University of Oxford)

31 May 2019

Delivering the 17th Wolfson Lecture, on 29th May, Professor Hugh Watkins guided a capacity audience through a measured and cautionary assessment of the extent to which genomics can predict and stratify disease risk, making a careful and convincing case that variants of uncertain significance form the Achilles heel of genetic testing.

In a break with tradition for Wolfson lectures, he was then joined by Professors David Hunter (Translational Epidemiology, University of Oxford) and Carmine Pariante (Biological Psychiatry, Kings College London), who led the floor in a lively debate covering the usefulness of polygenic risk scores, the extensive array of variants found for breast cancer, the significance of genomic medicine in predicting mental health problems, and the ramifications of commercial genetic testing.

The Wolfson Institute is grateful to all three invited speakers for their thought provoking and spirited presentations.

From left to right: Professors Carmine Pariante, Hugh Watkins, David Hunter and Jack Cuzick.