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Wolfson Institute of Preventive Medicine - Barts and The London

Dr Ivana Sestak


Reader in Medical Statistics

Telephone: Tel: +44 (0) 20 7882 3522


I am a Reader in Medical Statistics with several years’ experience in breast cancer prevention trials and project management of clinical trials. My main research interests lie in the prediction of (late) breast cancer recurrence ( and how we can identify women who may benefit from treatment. The evaluation of several prognostic signatures for breast cancer has shown that they can predict recurrences in postmenopausal women and they might help clinicians in treatment decision making.

Over the past 10 years I have been the main medical statistician for several major prevention trials where we found that endocrine therapy prevents the occurrence of breast cancer in women at high risk of developing the disease. These findings have also been taken into consideration by the National Institute for Health and Care Excellence to extend their guidelines in terms of endocrine drugs for the prevention of breast cancer.


  • IBIS-2
  • Prevention of Hormone Related Cancers
  • Prevention & Screening CPTU
  • Collaboration toward Joint Analysis of DCIS data


Breast cancer chemoprevention
Breast cancer epidemiology