Wolfson Institute of Preventive Medicine - Barts and The London

Dr Georgina Hosang

Georgina

Senior Lecturer in Mental Illness & Chronic Diseases, Centre for Psychiatry

Email: g.hosang@qmul.ac.uk
Telephone: Tel: +44 (0)020 7882 2017
Room Number: 2.07 Old Anatomy Building

Profile

Dr Georgina Hosang is a Senior Lecturer in Mental Illness and Chronic Diseases, at the Centre for Psychiatry, appointed in 2017. She completed her PhD in Social, Genetic and Developmental Psychiatry at the Institute of Psychiatry, Psychology and Neuroscience, King’s College London and was then awarded the prestigious ESRC/MRC Interdisciplinary Postdoctoral Fellowship. She was appointed as a Psychology Lecturer at Middlesex University in 2012 and the following year moved to the Psychology Department at Goldsmiths, University of London. Dr Hosang’s work has been funded by the ESRC, MRC, the Richard Benjamin Trust, International Bipolar Foundation and Barts Charity. Georgina is the recipient of the Eli Lilly International Fellowship in Bipolar Disorder (2013) and the Samuel Gershon Junior Investigator Award (2019) both awarded by the International Society for Bipolar Disorders in recognition of her research contribution to the area.

 

Research

1) Life stress, mental and physical illness

Dr Hosang’s research centres on the role of life stress (e.g., stressful life events and childhood adversities) on mood disorders (i.e., bipolar disorder and depression), physical illnesses (e.g., cardiovascular disease) and the comorbidity between the two.  She is keen to explore factors that either make people vulnerable or buffer them from the adverse effects of stress.

2) Gene x life stress interactions in mood disorders

Dr Hosang’s research has shown that a variant in the brain-derived neurotrophic factor gene may make people vulnerable to bipolar disorder and depression in the face of life stress.  One of her recent papers has provided initial evidence for the interaction between life stress and a polymorphism in the COMT gene in bipolar disorder.

3) Hypomania in youths

Georgina is interested in the characterization and development of hypomanic symptoms in youths.  Her work also examines the genetic and environmental architecture of its co-occurrence with other forms of psychopathology (eg. ADHD).

Publications

Hosang, GM, Fisher, HL, Hodgson, K, et al. (2018). Childhood maltreatment and adult medical morbidity in mood disorders: a comparison of unipolar depression with bipolar disorder. British Journal of Psychiatry, 213 (5), 645-653.

Hosang, GM, Fisher, HL, Uher, R. et al (2017). The medical burden in bipolar disorder: the role of childhood maltreatment. International Journal of Bipolar Disorder, 5, 30.

Hosang, GM, Johnson, SLKiecolt-Glaser, J, et al (2013). Gender specific association of child abuse and adult cardiovascular disease in a sample of patients with Basal Cell Carcinoma. Child Abuse and Neglect, 37(6):374-379.

Hosang, GM, Korszun, A, Jones, L. et al. (2012). Life event specificity: Bipolar disorder compared to unipolar depression. British Journal of Psychiatry, 201, 458–465.

Hosang, GM, Fisher, HL, Cohen-Woods, S, McGuffin, P & Farmer, A. (2017). Stressful life events and Catechol-O-methyl-transferase (COMT) gene in bipolar disorder. Depression and Anxiety, 34(5): 419-426.

Hosang, GM, Shiles, C, Tansey, T, McGuffin, P & Uher, R. (2014). Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis. BMC Medicine, 12:7.

Hosang, GM., Uher, R, Keers, R et al. (2010). Stressful life events and BDNF in Bipolar Disorder. Journal of Affective Disorders125, 345–349. 

Full list of publications can be found here: https://scholar.google.co.uk/citations?hl=en&user=zOwE38MAAAAJ&view_op=list_works