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The William Harvey Research Institute - Barts and The London

News from 2016 - 2017


November 2017

UK obesity levels among worst in Europe
A decline in deaths from heart attack and stroke in high-income countries could be threatened by rising rates of obesity and diabetes, according to a study led by Barts Heart Centre, Queen Mary University of London (QMUL).

Drug could cut transplant rejection
A diabetes drug currently undergoing development could be repurposed to help end transplant rejection, without the side-effects of current immunosuppressive drugs, according to new research by Queen Mary University of London (QMUL).

Four QMUL researchers in the top 1 per cent
Researchers from the William Harvey Research Institute have been placed in the top 1 percent in the world, in this year’s Highly Cited Researchers list.

October 2017 

High BMI and blood pressure create heavy heart
Being overweight or obese creates damaging changes to the structure of the heart, according to new research led by Queen Mary University of London (QMUL).

September 2017

World's largest inflammatory disease biobank will enable more precise treatment
Researchers at Barts and the London School of Medicine and Dentistry have successfully been awarded a £1.7 million grant as part of a consortium led by the University of Glasgow to create the world's largest Immune Disease (IMID) Biobank.

Duchess of York visits the William Harvey Heart Centre
The Duchess of York was announced as an official British Heart Foundation (BHF) ambassador, marking the occasion by spending the morning at the William Harvey Heart Centre, Queen Mary University of London (QMUL).

August 2017

QMUL scientist shortlisted in national image competition
An image submitted by a British Heart Foundation-funded researcher at the Queen Mary University of London (QMUL) has made the shortlist in the charity's annual 'Reflections of Research' image competition.

July 2017

CHIAROSCURO: from war trials to clinical trials
In this commemoration of the emergence of the Nuremberg Code doctors and patients of the William Harvey Clinical Research Centre will examine its significance for present-day clinical trials. Ralph Koltai, approaching his 93rd year, will recall his work as a librarian for the prosecution at Nuremberg in conversation with David Collier, Clinical Director, with further contributions from Simon Callow will interview Ralph — probably the most famous stage designer alive today — with an illustrated commentary on his subsequent work for the stage.

June 2017

Study of the mouse genome reveals new gene functions and their role in human disease
The first results from a functional genetic catalogue of the laboratory mouse has been shared with the research community, revealing new insights into a range of rare diseases and the possibility of accelerating development of new treatments and precision medicine.

Genetic testing can pick out men at increased risk of testicular cancer
Testing for large numbers of genetic changes can identify men with over a 10-fold increased risk of testicular cancer, a new study shows. Researchers found that testing for newly identified genetic factors along with others found in their previous studies could pick out men at increased risk, who might potentially benefit from monitoring or preventative treatment.

Statins help improve heart structure and function
Statins can improve the structure and function of the heart, according to a new study by researchers at Queen Mary University of London (QMUL)

QMUL study finds link between diesel pollution and heart damage
Diesel fumes have negative effects on the heart according to a new study by researchers at Queen Mary University of London (QMUL). 

May 2017

New study finds loss of sacsin effects organisation of the cells cytoskeleton
ARSACS Foundation-funded scientists at QMUL McGill University and Università Vita-Salute San Raffaele have just published a research paper in the journal Human Molecular Genetics, which looks at the cytoskeleton in cells cultured from ARSACS patients.

Data suggests that the brain controls exercise capacity
A joint study by researchers from Queen Mary University of London (QMUL), University College London (UCL) and the University of Bristol suggests that the brain controls exercise capacity, a highly novel idea with ramifications for health in the general population as well as elite athletes.

Some statin-related side effects are due to 'nocebo' effect
Patients report more side effects when they know they are taking a statin, than when they do not know whether they are on the drug or a dummy pill, according to a study by researchers from Imperial College London and Queen Mary University of London (QMUL).

April 2017

Research Matters: Changing lives in east London and beyond
For International Clinical Trials Day 2017, Barts Health NHS Trust and QMUL’s School of Medicine and Dentistry will be hosting ‘Research Matters: changing lives in east London and beyond’The free event will feature talks from award-winning academics and clinicians, patients and others, to showcase high-quality clinical research and engage patients, families, carers and community leaders to act as research champions and encourage greater participation and involvement in healthcare research. 

March 2017

Winning photo reveals the latest in maternal health research
Dr Suchita Nadkarni has been announced as one of the winners of the Wellcome Image Awards 2017. The winning photo, titled The Pacenta Rainbow, is based on her research into pregnancy complications and will be shown at exhibitions held across the UK and internationally, including Russia and South Africa.

Success for WHRI researchers at the QMUL Engagement and Enterprise Awards
On Tuesday 7th February 2017 QMUL hosted the second annual Engagement and Enterprise Awards to celebrate and showcase projects demonstrating excellence in the application and dissemination of research and teaching through public engagement, academic innovation, media relations and student enterprise.

February 2017

Obesity leads to harmful activation of the immune system
WHRI researchers find a link between a high-fat diet, obesity and cardiovascular disease risk.

William Harvey New Year Celebration 2017
On Friday the 3rd of February the WHRI held its annual New Year Celebration and featured 15 talks from the institute's postgraduates and young post-docs.

Genetic defect found to cause disease in multiple organs
New research from Queen Mary University of London (QMUL) has identified a novel syndrome in patients with kidney and adrenal disease.

New genes for height revealed in global study of 700,000 people
Over 80 new genetic variants that strongly influence human height have been discovered in a study led by Queen Mary University of London (QMUL), Montreal Heart Institute, The Broad Institute and the University of Exeter.

WHRI hosts Church of England clergy visit
Church of England vicars paid a visit to the WHRI to experience clinical and genomic research at first hand, as part of a national initiative to help scientists and faith leaders engage in dialogue and enhance understanding of ethical issues in medicine.

January 2017

Over 100 new blood pressure genes could provide targets for treating hypertension
A study co-authored by Professor Mark Caulfield finds 107 new gene regions associated with high blood pressure, potentially enabling doctors to identify at-risk patients and target treatments.

Professor Fulvio D'Acquisto receives CPE award to establish the 'Young Science Knowledge network'
East London school teachers to be provided CPD support and workshops to connect local schools with the Frontiers for Young Minds initiative, an open-access scientific journal that publishes ground‐breaking science in language reviewed by teachers and their classes for accessibility.

Major Grant awarded to resolve debate on treatment after surgery
Queen Mary University of London (QMUL) awarded $1.5m (£1.2m) by Edwards Lifesciences to carry out a study into a debated therapy for preventing complications after major surgery.

How the brain helps the body fight bacteria
"The brain may not only control our thoughts and physical functions," writes Dr Jesmond Dalli in The Conversation.  

December 2016

White blood cell treatment could prevent leading cause of foetal death
Treating a type of white blood cell using hormones could improve the development of the placenta in women with pregnancy complications according to early research led by QMUL.

October 2016

Maternal blood test may predict birth complications
A protein found in the blood of pregnant women could be used to develop tests to determine the health of their babies and aid decisions on early elective deliveries, according to an early study led by WHRI's Dr Marika Charalambous.

Enzymes responsible for tissue repair
r Jesmond Dalli explains how his new research has uncovered enzymes that are crucial for the repair and regeneration of 
tissues, and could lead to new treatments for diseases such as rheumatoid arthritis.   

WHRI researchers identify link between immunity and 'holidays'         
A team of researchers at the WHRI are investigating ways in which holidays, music or a change of environment can bolster our immune systems in the fight against disease

September 2016 

WHRI researchers identify link between immunity and 'holidays'
hirty-one new gene regions linked with blood pressure have been identified in one of the largest genetic studies of blood pressure to date, involving over 347,000 people, and jointly led by Queen Mary University of London (QMUL) and the University of Cambridge.

July 2016 

A new hope for reducing uncontrollable blood pressure
At The Royal London Hospital, on 30 June 2016, the Barts Blood Pressure Clinic became the first hospital in the country to provide two NHS patients with the innovative Barostim Neo™ device that could transform and save the lives of people living with uncontrollable blood pressure. 

June 2016

The Fox Got You project visits WHRI for lab visit
London-based Swiss artist, 
horticulturist and founder of The Fox Got You project has recently published the findings from her visit to the William Harvey Research Institute. 

April 2016 

Parliamentarians pay visit to WHRI researchers
Chris Green MP, Stephen Timms MP and Baroness Neville-Jones were welcomed by researchers at Queen Mary University of London (QMUL) on a visit organised by the British Heart Foundation (BHF).