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The William Harvey Research Institute - Barts and The London

News archive

November 2019

Researchers find potential new target for treatment of inflammatory disease
A new joint study involving researchers from Queen Mary University of London has identified potential new targets to tackle lactate-induced chronic inflammation.   

Success for WHRI at the International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
Scientists from 21 countries travelled to St. Petersburg, Florida, USA last week to attend the 16th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, which is sponsored by the Eicosanoid Research Foundation.

August 2019

Researchers from the Centre for Endocrinology win 2019 EJE Readers' Choice Award for joint study into rare disease

Outstanding impact in teaching recognised in national award
Professor Maralyn Druce from Queen Mary University of London has been announced as a new National Teaching Fellow by Advance HE today. 

July 2019

Health tech start-up partners with the William Harvey Research Institute to develop personalised treatment for high blood pressure
Closed Loop Medicine (CLM), the Cambridge based therapeutics company that helps doctors and healthcare providers to deliver personalised treatment regimens, has raised £1.3 million in research grant funding from the InnovateUK Innovation Accelerator, Longwall Ventures and IQ Capital. 

WHRI Academic voted 2019 Teacher of the Year by MBBS students
We are pleased to announce that Dr Fu Liang Ng, Clinical Senior Lecturer in Clinical Pharmacology at the William Harvey Research Institute, was voted Teacher of the Year by the MBBS students for 2019. The award is in recognition of the dedication and hard that goes into the Medicine programme at the School of Medicine and Dentistry.

June 2019

2019 WHRI Annual Review Summary
The William Harvey Annual Review took place on the 12th of June 2019 at the Derek Willoughby Lecture Theatre, Charterhouse Square.

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
A new joint study involving researchers at Queen Mary University of London has identified background subclinical changes on the electrocardiodiagram as risk factors in cardiovascular mortality.

EMR delivers “Creating without constraint: Arthritis and art” at QMUL's Tate Exchange
The Centre for Experimental Medicine and Rheumatology (EMR) at the William Harvey Research Institute is committed to engaging with the public and has participated in the Barts and Queen Mary Science Festival for a number of years, offering children the opportunity to try gloves that simulate the effect of arthritis and to ‘see’ inside their joints using ultrasound, so when QMUL Arts and Culture asked for proposals for the 2019 Tate Exchange EMR decided to build on this and submit a project. 

Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Non-Cardiovascular Diseases
A new study by researchers at Queen Mary University of London has shown how genetic predisposition to coronary heart disease (including heart attacks) is genetically correlated to other diseases.   

Leading genomics expert awarded knighthood in the Queen's birthday honours
Professor Mark Caulfield, the interim Chief Executive at Genomics England and Professor of Clinical Pharmacology at Queen Mary University of London, has been awarded a knighthood in the Queen’s Birthday Honours List.

Coffee not as bad for heart and circulatory system as previously thought
Drinking coffee might keep us up at night, but new research has given us a reason to sleep easy knowing that the popular drink isn’t as bad for our arteries as some previous studies would suggest. 

May 2019

Follow us on LinkedIn
We are pleased to announce that we are now officially in LinkedIn. 

DNA discovery could have implications for mitochondrial donation treatment
Mitochondria, the ‘batteries’ that produce our energy, interact with the cell’s nucleus in subtle ways previously unseen in humans, according to research involving academics from Queen Mary University of London.

London heart disease patients take part in clinical trial test alternative to statins
A clinical trial, coordinated by researchers from Queen Mary University of London, is currently recruiting patients in London to see whether a new cholesterol-lowering drug could save lives in people who are intolerant to statins.

April 2019

Quality Improvement in emergency surgery shows no difference in patient survival
Researchers from Queen Mary University of London studied the effectiveness of one of the largest ever national quality improvement programmes in the National Health Service (NHS) and found no improvement in patient survival. 

March 2019

Poor lung function in shorter people linked to increased risk of heart disease
Results from a study led by researchers from Queen Mary University of London has found that an association between shorter stature and higher risk of heart disease is mainly attributed to our lungs. 

QMUL researchers seek new treatment for arthritis as part of EU-funded project
Researchers from Queen Mary University of London are about to start work on a new EU-funded project to discover novel therapeutic targets for osteoarthritis and rheumatoid arthritis. 

QMUL Researchers win prestigious award for Vascular Biology publication
A publication by researchers from the Centre for Microvascular Research at the William Harvey Research Institute has received the highly prestigious Servier Award in Microcirculation. 

BHF invests £34m in top universities, helping to safeguard UK’s world-class research status
The British Heart Foundation (BHF) has this week announced £34million of new funding across 12 universities, in a move that strengthens world-class, UK-led heart and circulatory disease research.

February 2019

Working long hours linked to depression in women
Women who work more than 55 hours a week are at a higher risk of depression compared to men, according to a UCL-led study with Queen Mary University of London.

Professor of Endocrine Medicine achieves recognition for Excellence in EducationThe winners of Queen Mary’s new scheme of annual Education Excellence Awards and President and Principal’s Prizes were announced at a ceremony on 20 February 2019.

Researcher named as one of the most inspirational women in science
Professor Federica Marelli-Berg from Queen Mary University of London has been named by the British Heart Foundation (BHF) as one of the top 10 inspirational women in science.

December 2018

Genomics project reaches goal of 100,000 genomes sequenced from NHS patients
UK Health Secretary Matt Hancock has today announced that a project involving Queen Mary University of London researchers has reached its goal of sequencing 100,000 whole genomes from NHS patients.

November 2018 

WHRI researchers in top 1 per cent worldwide
Three researchers from the William Harvey Research Institute have been placed in the top 1 per cent in the world, in this year's highly cited Researchers list.

Researcher in Focus
Dr Gloria Lliso-Ribera, Clinical Research Fellow at the Centre for Experimental Medicine and Rheumatology talks about life as a WHRI researcher. 

Professor Chris Thiemermann honoured for his contributions to science In October 2018, Chris Thiemermann, Professor of Pharmacology and Centre Lead for Translational Medicine & Therapeutics at the William Harvey Research Institute, received the prestigious Albert Nelson Marquis Lifetime Achievement Award.  

October 2018

Professor Márta Korbonits delivers inaugural Lady Estelle Wolfson lecture at RCP
Professor Márta Korbonits gave the Lady Estelle Wolfson lecture in translational medicine at the Royal College of Physicians on the 24th October 2018 during the Acute and General Medicine Conference. 

Genetic tool to predict adult heart disease risk in childhood
People at high risk of a heart attack in adulthood could be identified much earlier in life with a one-off DNA test, according to new research published in the Journal of the American College of Cardiology.

September 2018

Landmark TB research announced at the UN General Assembly
A landmark international research project, involving researchers from Queen Mary University of London, has shown that we can now use our knowledge of the tuberculosis (TB) genetic code to predict which drugs are best for treating a patient’s infection.

Researchers awarded for lifetime achievements in blood pressure research
Two academics from Queen Mary University of London have received prestigious awards from the International Society of Hypertension (ISH) in recognition of their achievements in blood pressure research.
 

Study of one million people leads to world's biggest advance in blood pressure genetics
Over 500 new gene regions that influence people’s blood pressure have been discovered in the largest global genetic study of blood pressure to date, led by Queen Mary University of London and Imperial College London.

August 2018

Blood pressure medications and statins found to provide long-term cardiovascular benefits
Death rates from heart disease and stroke could be significantly lowered by prescribing statins alongside blood pressure-lowering drugs, according to the results from a clinical trial led by Queen Mary University of London and Imperial College London.

New research links low levels of air pollution with serious changes in the heart

July 2018

Graduation joy for WHRI Pharmacology students
On Thursday 26 July 2018, the first ever cohort of students from our 
BSc Pharmacology and Innovative Therapeutics programme were honoured at the QMUL Graduation Ceremony at the Mile End Campus. 

ESE’s Scientific Programme Chair discusses Brexit effects on European Reference Network in the UK Parliament
Professor Márta Korbonits, Professor of Endocrinology at Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Scientific Programme Chair of the European Society of Endocrinology, and representative of BioMed Alliance, will be discussing the effects of Brexit on the European Reference Networks (ERNs), in Westminster, Monday 9 July.

June 2018

Q&A with Dr Li Chan 
Research paper: MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.

New lab technology could reveal treatments for muscle-wasting disease
Researchers from Queen Mary University of London have developed new cell-based technologies which could improve understanding of the muscle-wasting disease Duchenne muscular dystrophy (DMD) and test potential drugs for the disease.  

May 2018

Surgery involving ultrasound energy found to treat high blood pressure
An operation that targets the nerves connected to the kidney has been found to significantly reduce blood pressure in patients with hypertension, according to the results of a clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust, and supported by the National Institute for Health Research (NIHR).

Lunch & Learn: Cutting Edge Studies in Autoimmune disease
Crown Bioscience and 
Dr. Ahuva Nissim, Queen Mary University of London, are delighted to invite you to attend our Lunch and Learn Seminar on Cutting Edge Studies in Autoimmune Disease on 1 June 2018. 

May 2018

QMUL and UCL joint study identifies genes linked to impaired capacity to modulate heart rate during and after exercise
A new study by researchers at Queen Mary University of London (QMUL) and University College London (UCL) has discovered 30 new gene locations that determine how the heart responds to and recovers from exercise.

Fellows inaugurated at new Rutherford Academy of Population Genomics and Health Data Science
Queen Mary University of London has appointed four research fellows to its new Rutherford Academy of Population Genomics and Health Data Science, funded by the Medical Research Council and UK Research and Innovation's Rutherford Fund
.

Professor Panos Deloukas elected as Fellow of The Academy of Medical Sciences
Professor of Cardiovascular Genomics at the William Harvey Research Institute has been recognised for contributions to genomic medicine.

April 2018

Professor Gustav Born: 29th July 1921 - 16 April 2018
A message on 
behalf of Professor Steve Thornton, Vice Principal (Health).
 

Pint of Science Festival, 14-16 May 2018
Pint of Science QMUL brings scientists out of the lab and into your local pub. Tickets are now available for the world's largest festival of public science talks, which will see >25 QMUL scientists take to the stage in pubs across London. 

Hormone imbalance causes treatment-resistsance hypertension
British researchers have discovered a hormone imbalance that explains why it is very difficult to control blood pressure in around 10 per cent of hypertension patients.  

March 2018

New project to transform treatment for children with arthritis
Researchers from Queen Mary University of London will join a UK-wide effort to drive the development of new treatments for children and young people with juvenile idiopathic arthritis (JIA) and its associated eye-inflammation condition, uveitis.

Weak hand grip could be sign of a failing heart
Hand grip strength could be used as a simple measure of heart health, according to new research led by scientists at Queen Mary University of London.

Menopausal hormone therapy linked to having a healthier heart 
Women who use menopausal hormone therapy appear to have a heart structure and function that is linked to a lower risk of heart failure, according to a study led by Queen Mary University of London.

New insights into why patients have a higher risk of heart attack in the morning
Cardiovascular disease patients have lower levels of an important family of protective molecules in their blood in the morning, which could be increasing their risk of blood clots and heart attacks at those times, according to early research led by Queen Mary University of London.

Aspirin helps treat tuberculous meningitis
The painkiller aspirin appears to reduce the risk of stroke and death in patients with the most deadly form of tuberculosis, according to a study by Queen Mary University of London, Oxford University Clinical Research Unit (Vietnam), Western General Hospital and University of Oxford.

Isolated white blood cell packages from patients with rheumatoid arthritis shown to be protective against inflammation
A new study by researchers from Queen Mary University of London finds that small packages released by white blood cells during inflammation can be used to prevent the activation of other white blood cells.  

February 2018

Dr Suchita Nadkarni's 'The Placenta Rainbow' featured in National Geographic
Photo by William Harvey Research Institute and British Heart Foundation (BHF) Research Fellow shows differences in mouse placental development that can result from manipulation of the mother’s immune system.

“Beetroot pill” may help save patients from kidney failure after heart x-ray
Beetroot may reduce the risk of kidney failure in patients having a heart x-ray, according to research led by Queen Mary University of London.

£54 million award to transform health through data science
Queen Mary University of London has partnered with four other London universities - UCL, Imperial College London, King's College London and The London School of Hygiene & Tropical Medicine - in a new initiative to transform health through data science.

100,000 Genomes Project to sequence its 500th genome later this month
Professor Mark Caulfield spoke to Observer Science Editor Robin McKie about the pioneering work of the 100,000 Genomes Project as it approaches its halfway point.

Multinational companies continue to produce unregulated antibiotics in India
Millions of unapproved antibiotics are being sold in India, according to a new joint study led by Dr Patricia McGettigan from the William Harvey Research Institute.

January 2018

The first step in generating an artificial adrenal gland
In a new study, published in Cell Reports, researchers from Queen Mary University of London used cells derived from urine to take the first step in generating an artificial adrenal gland, which could help develop future treatments for adrenal gland disorders.

Diabetes gene found that causes low and high blood sugar levels in the same family
A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.

November 2017

UK obesity levels among worst in Europe
A decline in deaths from heart attack and stroke in high-income countries could be threatened by rising rates of obesity and diabetes, according to a study led by Barts Heart Centre, Queen Mary University of London (QMUL).

Drug could cut transplant rejection
A diabetes drug currently undergoing development could be repurposed to help end transplant rejection, without the side-effects of current immunosuppressive drugs, according to new research by Queen Mary University of London (QMUL).

Four QMUL researchers in the top 1 per cent
Researchers from the William Harvey Research Institute have been placed in the top 1 percent in the world, in this year’s Highly Cited Researchers list.

October 2017 

High BMI and blood pressure create heavy heart
Being overweight or obese creates damaging changes to the structure of the heart, according to new research led by Queen Mary University of London (QMUL).

September 2017

World's largest inflammatory disease biobank will enable more precise treatment
Researchers at Barts and the London School of Medicine and Dentistry have successfully been awarded a £1.7 million grant as part of a consortium led by the University of Glasgow to create the world's largest Immune Disease (IMID) Biobank.

Duchess of York visits the William Harvey Heart Centre
The Duchess of York was announced as an official British Heart Foundation (BHF) ambassador, marking the occasion by spending the morning at the William Harvey Heart Centre, Queen Mary University of London (QMUL).

August 2017

QMUL scientist shortlisted in national image competition
An image submitted by a British Heart Foundation-funded researcher at the Queen Mary University of London (QMUL) has made the shortlist in the charity's annual 'Reflections of Research' image competition.

July 2017

CHIAROSCURO: from war trials to clinical trials
In this commemoration of the emergence of the Nuremberg Code doctors and patients of the William Harvey Clinical Research Centre will examine its significance for present-day clinical trials. Ralph Koltai, approaching his 93rd year, will recall his work as a librarian for the prosecution at Nuremberg in conversation with David Collier, Clinical Director, with further contributions from Simon Callow will interview Ralph — probably the most famous stage designer alive today — with an illustrated commentary on his subsequent work for the stage.

June 2017

Study of the mouse genome reveals new gene functions and their role in human disease
The first results from a functional genetic catalogue of the laboratory mouse has been shared with the research community, revealing new insights into a range of rare diseases and the possibility of accelerating development of new treatments and precision medicine.

Genetic testing can pick out men at increased risk of testicular cancer
Testing for large numbers of genetic changes can identify men with over a 10-fold increased risk of testicular cancer, a new study shows. Researchers found that testing for newly identified genetic factors along with others found in their previous studies could pick out men at increased risk, who might potentially benefit from monitoring or preventative treatment.

Statins help improve heart structure and function
Statins can improve the structure and function of the heart, according to a new study by researchers at Queen Mary University of London (QMUL)

QMUL study finds link between diesel pollution and heart damage
Diesel fumes have negative effects on the heart according to a new study by researchers at Queen Mary University of London (QMUL). 

May 2017

New study finds loss of sacsin effects organisation of the cells cytoskeleton
ARSACS Foundation-funded scientists at QMUL McGill University and Università Vita-Salute San Raffaele have just published a research paper in the journal Human Molecular Genetics, which looks at the cytoskeleton in cells cultured from ARSACS patients.

Data suggests that the brain controls exercise capacity
A joint study by researchers from Queen Mary University of London (QMUL), University College London (UCL) and the University of Bristol suggests that the brain controls exercise capacity, a highly novel idea with ramifications for health in the general population as well as elite athletes.

Some statin-related side effects are due to 'nocebo' effect
Patients report more side effects when they know they are taking a statin, than when they do not know whether they are on the drug or a dummy pill, according to a study by researchers from Imperial College London and Queen Mary University of London (QMUL).

April 2017

Research Matters: Changing lives in east London and beyond
For International Clinical Trials Day 2017, Barts Health NHS Trust and QMUL’s School of Medicine and Dentistry will be hosting ‘Research Matters: changing lives in east London and beyond’The free event will feature talks from award-winning academics and clinicians, patients and others, to showcase high-quality clinical research and engage patients, families, carers and community leaders to act as research champions and encourage greater participation and involvement in healthcare research. 

March 2017

Winning photo reveals the latest in maternal health research
Dr Suchita Nadkarni has been announced as one of the winners of the Wellcome Image Awards 2017. The winning photo, titled The Pacenta Rainbow, is based on her research into pregnancy complications and will be shown at exhibitions held across the UK and internationally, including Russia and South Africa.

Success for WHRI researchers at the QMUL Engagement and Enterprise Awards
On Tuesday 7th February 2017 QMUL hosted the second annual Engagement and Enterprise Awards to celebrate and showcase projects demonstrating excellence in the application and dissemination of research and teaching through public engagement, academic innovation, media relations and student enterprise.

February 2017

Obesity leads to harmful activation of the immune system
WHRI researchers find a link between a high-fat diet, obesity and cardiovascular disease risk.

William Harvey New Year Celebration 2017
On Friday the 3rd of February the WHRI held its annual New Year Celebration and featured 15 talks from the institute's postgraduates and young post-docs.

Genetic defect found to cause disease in multiple organs
New research from Queen Mary University of London (QMUL) has identified a novel syndrome in patients with kidney and adrenal disease.

New genes for height revealed in global study of 700,000 people
Over 80 new genetic variants that strongly influence human height have been discovered in a study led by Queen Mary University of London (QMUL), Montreal Heart Institute, The Broad Institute and the University of Exeter.

WHRI hosts Church of England clergy visit
Church of England vicars paid a visit to the WHRI to experience clinical and genomic research at first hand, as part of a national initiative to help scientists and faith leaders engage in dialogue and enhance understanding of ethical issues in medicine.

January 2017

Over 100 new blood pressure genes could provide targets for treating hypertension
A study co-authored by Professor Mark Caulfield finds 107 new gene regions associated with high blood pressure, potentially enabling doctors to identify at-risk patients and target treatments.

Professor Fulvio D'Acquisto receives CPE award to establish the 'Young Science Knowledge network'
East London school teachers to be provided CPD support and workshops to connect local schools with the Frontiers for Young Minds initiative, an open-access scientific journal that publishes ground‐breaking science in language reviewed by teachers and their classes for accessibility.

Major Grant awarded to resolve debate on treatment after surgery
Queen Mary University of London (QMUL) awarded $1.5m (£1.2m) by Edwards Lifesciences to carry out a study into a debated therapy for preventing complications after major surgery.

How the brain helps the body fight bacteria
"The brain may not only control our thoughts and physical functions," writes Dr Jesmond Dalli in The Conversation.  

December 2016

White blood cell treatment could prevent leading cause of foetal death
Treating a type of white blood cell using hormones could improve the development of the placenta in women with pregnancy complications according to early research led by QMUL.

October 2016

Maternal blood test may predict birth complications
A protein found in the blood of pregnant women could be used to develop tests to determine the health of their babies and aid decisions on early elective deliveries, according to an early study led by WHRI's Dr Marika Charalambous.

Enzymes responsible for tissue repair
D
r Jesmond Dalli explains how his new research has uncovered enzymes that are crucial for the repair and regeneration of 
tissues, and could lead to new treatments for diseases such as rheumatoid arthritis.   


WHRI researchers identify link between immunity and 'holidays'         
A team of researchers at the WHRI are investigating ways in which holidays, music or a change of environment can bolster our immune systems in the fight against disease

September 2016 

WHRI researchers identify link between immunity and 'holidays'
T
hirty-one new gene regions linked with blood pressure have been identified in one of the largest genetic studies of blood pressure to date, involving over 347,000 people, and jointly led by Queen Mary University of London (QMUL) and the University of Cambridge.
 

July 2016 

A new hope for reducing uncontrollable blood pressure
At The Royal London Hospital, on 30 June 2016, the Barts Blood Pressure Clinic became the first hospital in the country to provide two NHS patients with the innovative Barostim Neo™ device that could transform and save the lives of people living with uncontrollable blood pressure. 

June 2016

The Fox Got You project visits WHRI for lab visit
London-based Swiss artist, 
horticulturist and founder of The Fox Got You project has recently published the findings from her visit to the William Harvey Research Institute. 

April 2016 

Parliamentarians pay visit to WHRI researchers
Chris Green MP, Stephen Timms MP and Baroness Neville-Jones were welcomed by researchers at Queen Mary University of London (QMUL) on a visit organised by the British Heart Foundation (BHF). 

December 2015 

WHRI was awarded a major recognition from the British Pharmacological Society
WHRI receives a major recognition from the British Pharmacological Society. The 'UK Pharmacology on the Map' award was presented to the WHRI for its outstanding contribution to the discovery and development of medicines.

November 2015

Amrita Ahluwalia awarded Women in Science and Engineering prize
Professor Amrita Ahluwalia from Queen Mary University of London (QMUL) has been awarded the 2015 Prize for Research by the WISE (Women in Science and Engineering) Campaign.

September 2015

Professors Mark Caulfield, Panos Deloukas and Patricia Munroe from the William Harvey Institute are within the top one percent most highly cited in the field of Molecular Biology & Genetics
Four QMUL colleagues have been named in the top cited researchers, as released by Thomson Reuters. 

December 2014

The results of the Research Excellence Framework (REF2014) bring excellent news for the WHRI and our mother organisations
The results of the Research Excellence Framework (REF), published today, confirm Queen Mary University of London (QMUL)’s place in the very top group of research-led universities.