List of Families and Subfamilies of the TC System (continued)

Family 2

2. Electrochemical-Potential-Driven Transporters
2.A Transporters or Carriers (uniporters, symporters and antiporters)
2.A.1	Major facilitator superfamily	MFS
2.A.1.1	Sugar porter	SP
2.A.1.2	Drug:H⁺ antiporter-1 (12 transmembrane segments)	DHA1
2.A.1.3	Drug:H⁺ antiporter-2 (14 transmembane segments)	DHA2
2.A.1.4	Organic phosphate:P_i antiporter	OPA
2.A.1.5	Oligosaccharide,H⁺ symporter	OHS
2.A.1.6	Metabolite,H⁺ symporter	MHS
2.A.1.7	Fucose,H⁺ symporter	FHS
2.A.1.8	Nitrate/nitrite porter	NNP
2.A.1.9	Phosphate,H⁺ symporter	PHS
2.A.1.10	Nucleoside,H⁺ symporter	NHS
2.A.1.11	Oxalate:formate antiporter	OFA
2.A.1.12	Sialate,H⁺ symporter	SHS
2.A.1.13	Monocarboxylate porter	MCP
2.A.1.14	Anion,cation symporter	ACS
2.A.1.15	Aromatic acid,H⁺ symporter	AAHS
2.A.1.16	Siderophore-iron transporter	SIT
2.A.1.17	Cyanate porter	CP
2.A.1.18	Polyol porter	PP
2.A.1.19	Organic cation transporter	OCT
2.A.1.20	Sugar efflux transporter	SET
2.A.1.21	Drug:H⁺ antiporter-3 (12 transmembrane segments)	DHA3
2.A.1.22	Vesicular neurotransmitter transporter	VNT
2.A.1.23	Conjugated bile salt transporter	BST
2.A.1.24	Unknown major facilitator-1	UMF1
2.A.1.25	Peptide-acetyl-CoA transporter	PAT
2.A.1.26	Unknown major facilitator-2	UMF2
2.A.1.27	Phenylpropionate permease	PPP
2.A.1.28	Unknown major facilitator-3	UMF3
2.A.1.29	Unknown major facilitator-4	UMF4
2.A.1.30	Putative abietane diterpenoid transporter	ADT
2.A.1.31	Nickel resistance mediator	Nre
2.A.1.32	Putative aromatic compound/drug exporter	ACDE
2.A.1.33	Putative YqgE transporter	YqgE
2.A.1.34	Feline leukemia virus subgroup C receptor	FLVCR
2.A.1.35	Fosmidomycin resistance mediator	Fsr
2.A.1.36	Acriflavin sensitivity mediator	YnfM
2.A.1.37	Putative short-chain fatty-acid porter	AtoE
2.A.2	Glycoside/pentoside/hexuronide,cation symporter	GPH
2.A.3	Amino acid/polyamine-organic cation superfamily	APC
2.A.3.1	Amino acid transporter	AAT
2.A.3.2	Basic amino acid:polyamine antiporter	APA
2.A.3.3	Cationic amino acid transporter	CAT
2.A.3.4	Amino acid/choline transporter	ACT
2.A.3.5	Ethanolamine transporter	EAT
2.A.3.6	Archaeal/bacterial transporter	ABT
2.A.3.7	Glutamate:g-aminobutyrate antiporter	GA
2.A.3.8	l-amino acid transporter	LAT
2.A.3.9	Spore germination protein	SGP
2.A.3.10	Yeast amino acid transporter	YAT
2.A.4	Cation diffusion facilitator	CDF
2.A.5	Zn²⁺-Fe²⁺ transporter (aka permease)	ZIP
2.A.6	Resistance-nodulation-cell division factor superfamily	RND
2.A.6.1	Heavy-metal exporter	HME
2.A.6.2	Hydrophobic/amphiphilic exporter-1 (mainly G^- bacteria)	HAE1
2.A.6.3	Putative nodulation factor exporter	NFE
2.A.6.4	Secretory accessory protein	SecDF
2.A.6.5	Hydrophobic/amphiphilic exporter-2 (G⁺ bacteria)	HAE2
2.A.6.6	Eukaryotic sterol transporter	EST
2.A.6.7	Hydrophobic/amphiphilic exporter-3 (mainly Archaea)	HAE3
2.A.7	Drug/metabolite transporter superfamily	DMT
2.A.7.1	4-TMS small multidrug resistance protein	SMR
2.A.7.2	5-TMS bacterial/archaeal transporter	BAT
2.A.7.3	10-TMS drug/metabolite exporter	DME
2.A.7.4	Plant drug/metabolite exporter	P-DME
2.A.7.5	Glucose/ribose porter	GRP
2.A.7.6	L-Rhamnose transporter	RhaT
2.A.7.7	Chloramphenicol-sensitivity protein	RarD
2.A.7.8	Caenorhabditis elegans open reading frame	CEO
2.A.7.9	Triose-phosphate transporter	TPT
2.A.7.10	UDP-N-acetylglucosamine:UMP antiporter	UAA
2.A.7.11	UDP-galactose:UMP antiporter	UGA
2.A.7.12	CMP-sialate:CMP antiporter	CSA
2.A.7.13	GDP-mannose:GMP antiporter	GMA
2.A.7.14	Plant organic cation porter (aka permease)	POP
2.A.8	Gluconate,H⁺ symporter	GntP
2.A.9	Cytochrome oxidase biogenesis factor	Oxa1
2.A.10	D-erythro-3-Deoxyhexulosonate ^a transporter	KDGT
2.A.11	Citrate-Mg²⁺,H⁺ (CitM) or Citrate-Ca²⁺,H⁺ (CitH) symporter	CitMHS
2.A.12	ATP:ADP antiporter	AAA
2.A.13	C₄-dicarboxylate importer	Dcu
2.A.14	Lactate transporter (aka permease)	LctP
2.A.15	Betaine/carnitine/choline transporter	BCCT
2.A.16	Tellurite-resistance/dicarboxylate transporter	TDT
2.A.17	Proton-dependent oligopeptide transporter	POT
2.A.18	Amino acid/auxin transporter (aka permease)	AAAP
2.A.19	Ca²⁺:cation antiporter	CaCA
2.A.20	Inorganic phosphate transporter	PiT
2.A.21	Solute,Na⁺ symporter	SSS
2.A.22	Neurotransmitter,Na⁺ symporter	NSS
2.A.23	Dicarboxylate/amino acid,cation (Na⁺ or H⁺) symporter	DAACS
2.A.24	Citrate,cation symporter	CCS
2.A.25	Alanine/glycine,cation symporter	AGCS
2.A.26	Branched-chain amino acid,cation symporter	LIVCS
2.A.27	Glutamate,Na⁺ symporter	ESS
2.A.28	Bile acid,Na⁺ symporter	BASS
2.A.29	Mitochondrial carrier	MC
2.A.30	Cation,chloride symporter (aka cotransporter)	CCC
2.A.31	Anion exchanger	AE
2.A.32	Silicate transporter	Sit
2.A.33	NhaA Na⁺:H⁺ antiporter	NhaA
2.A.34	NhaB Na⁺:H⁺ antiporter	NhaB
2.A.35	NhaC Na⁺:H⁺ antiporter	NhaC
2.A.36	Univalent cation:H⁺ antiporter-1	CPA1
2.A.37	Univalent cation:H⁺ antiporter-2	CPA2
2.A.38	K⁺ transporter	Trk
2.A.39	Nucleobase,cation symporter-1	NCS1
2.A.40	Nucleobase,cation symporter-2	NCS2
2.A.41	Concentrative nucleoside transporter	CNT
2.A.42	Hydroxy/aromatic amino acid porter (aka permease)	HAAAP
2.A.43	Lysosomal cystine transporter	LCT
2.A.44	Formate/nitrite transporter	FNT
2.A.45	Arsenite/antimonite exporter	ArsB
2.A.46	Benzoate,H⁺ symporter	BenE
2.A.47	Divalent anion,Na⁺ symporter	DASS
2.A.48	Reduced folate carrier	RFC
2.A.49	Ammonium transporter	Amt
2.A.50	Glycerol uptake porter	GUP
2.A.51	Chromate ion transporter	CHR
2.A.52	Ni²⁺/Co²⁺ transporter	NiCoT
2.A.53	Sulfate porter (aka permease)	SulP
2.A.54	Mitochondrial tricarboxylate carrier	MTC
2.A.55	Metal ion (Mn²⁺/Fe²⁺) transporter	Nramp
2.A.56	Tripartite ATP-independent periplasmic transporter	TRAP-T
2.A.57	Equilibrative nucleoside transporter	ENT
2.A.58	Phosphate,Na⁺ symporter	PNaS
2.A.59	Arsenical resistance factor-3	ACR3
2.A.60	Organic anion transporter	OAT
2.A.61	C4-dicarboxylate importer C	DcuC
2.A.62	NhaD Na⁺:H⁺ antiporter	NhaD
2.A.63	Univalent cation (K⁺ or Na⁺):H⁺ antiporter-3	CPA3
2.A.64	Type V secretory pathway protein (twin arginine targeting)	Tat
2.A.65	Bilirubin transporter	BRT
2.A.66	Multi-antimicrobial extrusion factor	MATE
2.A.67	Oligopeptide transporter	OPT
2.A.68	p-Aminobenzoylglutamate transporter	AbgT
2.A.69	Auxin efflux carrier	AEC
2.A.70	Malonate,Na⁺ symporter	MSS
2.A.71	Folate/biopterin transporter	FBT
2.A.72	K⁺ uptake porter (aka permease)	KUP
2.A.73	Inorganic carbon transporter	ICT
2.A.74	4-TMS multidrug endosomal transporter	MET
2.A.75	L-Lysine exporter	LysE
2.A.76	Resistance factor to homoserine/threonine	RhtB
2.A.77	Cadmium resistance factor	CadD
2.A.78	Branched-chain amino acid exporter	LIV-E
2.A.79	Threonine/serine exporter	ThrE
2.A.80	Tricarboxylate transporter	Tct

2.B Non-ribosomally synthesized transporters

2.B.1 Valinomycin Valinomycin

2.B.2 Monensin Monensin

2.B.3 Nigericin Nigericin

2.B.4 Macrotetrolide ntibiotic MA

2.B.5 Macrocyclic polyether MP

2.B.6 Ionomycin Ionomycin

^a D-erythro-3-Deoxyhexulosonate was formerly called 2-keto-3-deoxygluconate hence the family name KDGT; it may also be described as 2-dehydro-3-deoxy-D-gluconate.

Continued with List of Family 3
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Return to Biochemical Nomenclature home page

2.B Non-ribosomally synthesized transporters
2.B.1	Valinomycin	Valinomycin
2.B.2	Monensin	Monensin
2.B.3	Nigericin	Nigericin
2.B.4	Macrotetrolide ntibiotic	MA
2.B.5	Macrocyclic polyether	MP
2.B.6	Ionomycin	Ionomycin