IUBMB Enzyme Nomenclature

EC 7.3.2.5

Accepted name: ABC-type molybdate transporter

Reaction: ATP + H2O + molybdate-[molybdate-binding protein][side 1] = ADP + phosphate + molybdate[side 2] + [molybdate-binding protein][side 1]

Glossary: molybdate = tetraoxidomolybdate(2-) = MoO42-

Other name(s): molybdate ABC transporter; molybdate-transporting ATPase

Systematic name: ATP phosphohydrolase (ABC-type, molybdate-importing)

Comments: An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity import of molybdate and tungstate. Does not undergo phosphorylation during the transport process.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res. Microbiol. 146 (1995) 271-278. [PMID: 7569321]

2. Grunden, A.M. and Shanmugam, K.T. Molybdate transport and regulation in bacteria. Arch. Mikrobiol. 168 (1997) 345-354. [PMID: 9325422]

3. Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81-136. [PMID: 9889977]

4. Griffiths, J.K. and Sansom, C.E. The Transporter Factsbook, Academic Press, San Diego, 1998.

[EC 7.3.2.5 created 2000 as EC 3.6.3.29, transferred 2018 to EC 7.3.2.5]


Return to EC 7.3.2 home page
Return to EC 7.3 home page
Return to EC 7 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page