IUBMB Enzyme Nomenclature

EC 7.2.2.7

Accepted name: ABC-type Fe3+ transporter

Reaction: ATP + H2O + Fe3+-[iron-binding protein][side 1] = ADP + phosphate + Fe3+[side 2] + [iron-binding protein][side 1]

Other name(s): Fe3+-transporting ATPase

Systematic name: ATP phosphohydrolase (ABC-type, Fe3+-transporting)

Comments: ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains. A bacterial enzyme that interacts with a periplasmic iron-binding protein to imports Fe3+ ions into the cytoplasm.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Angerer, A., Klupp, B. and Braun, V. Iron transport systems of Serratia marcescens. J. Bacteriol. 174 (1992) 1378-1387. [PMID: 1531225]

2. Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res. Microbiol. 146 (1995) 271-278. [PMID: 7569321]

3. Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81-136. [PMID: 9889977]

4. Khun, H.H., Kirby, S.D. and Lee, B.C. A Neisseria meningitidis fbp ABC mutant is incapable of using nonheme iron for growth. Infect. Immun. 66 (1998) 2330-2336. [PMID: 9573125]

[EC 7.2.2.7 created 2000 as EC 3.6.3.30, transferred 2018 to EC 7.2.2.7]


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