IUBMB Enzyme Nomenclature

EC 7.2.2.21

Accepted name: Cd2+-exporting ATPase

Reaction: ATP + H2O + Cd2+[side 1] = ADP + phosphate + Cd2+[side 2]

Other name(s): cadmium-translocating P-type ATPase; cadmium-exporting ATPase

Systematic name: ATP phosphohydrolase (Cd2+-exporting)

Comments: A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in protozoa, fungi and plants.

References:

1. Silver, S. and Ji, G. Newer systems for bacterial resistance to toxic heavy metals. Environ. Health Perspect. 102, Suppl. 3 (1994) 107-113. [PMID: 7843081]

2. Tsai, K.J. and Linet, A.L. Formation of a phosphorylated enzyme intermediate by the cadA Cd2+-ATPase. Arch. Biochem. Biophys. 305 (1993) 267-270. [PMID: 8373163]

[EC 7.2.2.21 created 2000 as EC 3.6.3.3, transferred 2019 to EC 7.2.2.21]


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