Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = marneral
Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, marneral-forming)
For diagram of reaction click here.
Comments: Marneral is a triterpenoid formed by Grob fragmentation of the A ring of 2,3-epoxy-2,3-dihydrosqualene during cyclization.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Xiong, Q., Wilson, W. K. and Matsuda, S. P. T. An Arabidopsis oxidosqualene cyclase catalyzes iridal skeleton formation by Grob fragmentation. Angew. Chem., Int. Ed. 45 (2006) 1285-1288. [PMID: 16425307]