IUBMB Enzyme Nomenclature

EC 5.1.1.16

Accepted name: protein-serine epimerase

Reaction: [protein]-L-serine = [protein]-D-serine

Other name(s): protein-serine racemase

Systematic name: [protein]-serine epimerase

Comments: the enzyme specifically interconverts the configuration of Ser-46 of the peptide ω-agatoxin-KT, found in the venom of the funnel web spider, Agelenopsis aperta, but not that of the other serine residue, Ser-28.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 169592-52-3

References:

1. Shikata, Y., Watanabe, T., Teramoto, T., Inoue, A., Kawakami, Y., Nishizawa, Y., Katayama, K., Kuwada, M. Isolation and characterization of a peptide isomerase from funnel web spider venom. J. Biol. Chem. 270 (1995) 16719-16723. [PMID: 7622482]

[EC 5.1.1.16 created 1999]


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